3-PYRIMIDIN-5-YL-BENZOIC ACID

Product Name: 3-PYRIMIDIN-5-YL-BENZOIC ACID
CAS No.: 852180-74-6
Chemical Name: 3-PYRIMIDIN-5-YL-BENZOIC ACID
Synonyms: P-017;3-(2-Methoxyp;AKOS BAR-0650;3-PYRIMIDIN-5-YL-BENZOIC ACID;3-(5-PYRIMIDINYL)BENZOIC ACID;3-PYRIMIDIN-5-YL-BENZOIC ACID, 95+%;Benzoic acid, 3-(5-pyrimidinyl)- (9CI);3-(2-Chloropyrimidin-5-yl)benzoic acid;3-(2,4-Dimethoxypyrimidin-5-yl)benzoic acid;3-(2-(Methylthio)pyrimidin-5-yl)benzoic acid
CBNumber: CB6299464
Molecular Formula: C11H8N2O2
Formula Weight: 200.19
MOL File: 852180-74-6.mol

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3-PYRIMIDIN-5-YL-BENZOIC ACID Property

storage temp.: Sealed in dry,Room Temperature
form: powder
color: Off-white

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Safety

Hazard Codes: Xn
Risk Statements: 22-36
Safety Statements: 26
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P997398
Product name: 3-Pyrimidin-5-yl-benzoicAcid
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Apolloscientific

Product number: OR913118
Product name: 3-Pyrimidin-5-ylbenzoicacid
Purity: 97%
Packaging: 1g
Price: $66
Updated: 2021/12/16

AK Scientific

Product number: W8798
Product name: 3-Pyrimidin-5-yl-benzoicacid
Packaging: 250mg
Price: $80
Updated: 2021/12/16

Apolloscientific

Product number: OR913118
Product name: 3-Pyrimidin-5-ylbenzoicacid
Purity: 97%
Packaging: 5g
Price: $122
Updated: 2021/12/16

Matrix Scientific

Product number: 071828
Product name: 3-Pyrimidin-5-yl-benzoic acid
Purity: 95+%
Packaging: 1g
Price: $208
Updated: 2021/12/16

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3-PYRIMIDIN-5-YL-BENZOIC ACID Chemical Properties,Usage,Production

Synthesis

4595-59-9

269409-73-6

852180-74-6

General method: 5-Bromopyrimidine (1.0 eq.) was dissolved in a solvent mixture of water and dioxane (1:1). Subsequently 3-carboxyphenylboronic acid pinacol ester (1.5 eq.) and potassium phosphate (5.0 eq.) were added. The reaction solution was degassed by vacuum/argon cycle (10 times) and further degassed (5 times) before addition of PdCl2(PPh3)2 (10 mol%). The resulting mixture was stirred and reacted at 95 °C and under argon protection for 16-20 hours. Upon completion of the reaction, the mixture was filtered through diatomaceous earth and diluted with about 30 mL of water and subsequently washed with chloroform (3 x 30 mL). Unless otherwise indicated, the aqueous phase was concentrated under reduced pressure and purified by C18 pre-column and further eluted on a 10g or 60g C18 column using gradient elution with aqueous acetonitrile (10-100%) to obtain the target product 3-pyrimidine-5-benzene carboxylic acid.

References

[1] European Journal of Medicinal Chemistry, 2018, vol. 145, p. 634 - 648
[2] Patent: WO2016/34673, 2016, A1. Location in patent: Page/Page column 80

3-PYRIMIDIN-5-YL-BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3-PYRIMIDIN-5-YL-BENZOIC ACID Suppliers

Belgium 1 China 55 Europe 1 Germany 1 India 1 Russia 1 United Kingdom 1 United States 11 Global 72

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Shandong Xiya Chemical Co., Ltd

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ShangHai YuanYe Biotechnology Co., Ltd.

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Email: shyysw007@163.com
Country: China
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Thermo Fisher Scientific

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Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
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Shanghai Topbiochem Technology Co., Ltd

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Country: China
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9ding chemical ( Shanghai) Limited

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Shanghai Carlow Chemicals Co., Ltd.

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Bide Pharmatech Ltd.

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Zhengzhou Guancheng Laboratory equipment Sales

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View Lastest Price from 3-PYRIMIDIN-5-YL-BENZOIC ACID manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Pyrimidin-5-ylbenzoic acid 852180-74-6
Price: US $1.00-1.00/Kg/Drum
Min. Order: 1g
Purity: 99%
Supply Ability: 20ton
Release date: 2020-05-14

Dideu Industries Group Limited

Product: 3-PYRIMIDIN-5-YL-BENZOIC ACID 852180-74-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons
Release date: 2022-02-17

852180-74-6, 3-PYRIMIDIN-5-YL-BENZOIC ACIDRelated Search:

4-(PYRIMIDIN-2-YL)BENZOIC ACID 4-(2-AMINOPYRIMIDIN-5-YL)BENZOIC ACID 3-(2-Aminopyrimidin-5-yl)benzoic acid 4-(2-(Methylthio)pyrimidin-5-yl)benzoic acid,4-PYRIMIDIN-5-YL-BENZOIC ACID 95%,4-PYRIMIDIN-5-YL-BENZOIC ACID 3-PYRIMIDIN-5-YL-BENZOIC ACID 3-(Pyrimidin-4-yl)benzoic acid 3-(PYRIMIDIN-2-YL)BENZOIC ACID 4-(2-Chloro-pyrimidin-4-yl)-benzoic acid 4-(Pyrimidin-4-yl)benzoic acid 4-PYRIMIDIN-5-YL-BENZOIC ACID ETHYL ESTER 4-(2,4,6-TRIOXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BENZOIC ACID 4-(6-ACETYL-1,3,7-TRIMETHYL-2,4-DIOXO-1,2,3,4,5,8-HEXAHYDROPYRIDO[2,3-D]PYRIMIDIN-5-YL)BENZOIC ACID 4-(2-Chloro-pyrimidin-4-yl)-benzoic acid ethyl ester 2-(2-Chloro-pyrimidin-4-yl)-benzoic acid 4-(7-ETHYL-4-OXO-3,4,5,6,7,8-HEXAHYDRO[1]BENZOTHIENO[2,3-D]PYRIMIDIN-2-YL)BENZOIC ACID 2-(2-Chloro-pyrimidin-4-yl)-benzoic acid methyl ester 3-(2-Chloro-pyrimidin-4-yl)-benzoic acid benzyl ester 4-(2-Chloro-pyrimidin-4-yl)-benzoic acid benzyl ester

3-(5-PYRIMIDINYL)BENZOIC ACID

3-PYRIMIDIN-5-YL-BENZOIC ACID

AKOS BAR-0650

3-(2-(Methylthio)pyrimidin-5-yl)benzoic acid

3-(2,4-Dimethoxypyrimidin-5-yl)benzoic acid

3-(2-Chloropyrimidin-5-yl)benzoic acid

3-(2-Methoxyp

3-(2-Oxo-1,2-dihydropyrimidin-5-yl)benzoic acid

3-(3-(Dimethylamino)-2-methoxypyrimidin-5-yl)benzoic acid

3-PYRIMIDIN-5-YL-BENZOIC ACID, 95+%

Benzoic acid, 3-(5-pyrimidinyl)- (9CI)

3-PYRIMIDIN-5-YL-BENZOIC ACID ISO 9001：2015 REACH

P-017

852180-74-6

PYRIMIDINE