ChemicalBook > CAS DataBase List > (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

(2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid

Product Name
(2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
CAS No.
1012341-52-4
Chemical Name
(2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
Synonyms
LCZ706;LCZ696-20;impurity 21;LCZ696696-A-A;LCZ696 impuritiesE;LCZ 696 Impurity E;LCZ-696 Impurity 17;LCZ696 impurities125;Sacubitril Impurity E;Sacubitril Impurity 2
CBNumber
CB62995777
Molecular Formula
C23H29NO4
Formula Weight
383.48
MOL File
1012341-52-4.mol
More
Less

(2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Property

Boiling point:
582.6±50.0 °C(Predicted)
Density 
1.115±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
4+-.0.23(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1/C23H29NO4/c1-16(21(25)26)14-20(24-22(27)28-23(2,3)4)15-17-10-12-19(13-11-17)18-8-6-5-7-9-18/h5-13,16,20H,14-15H2,1-4H3,(H,24,27)(H,25,26)/t16-,20-/s3
InChIKey
YNELJETWNMPEEH-HLGVANASNA-N
SMILES
C(O)(=O)[C@@H](C)C[C@H](NC(OC(C)(C)C)=O)CC1=CC=C(C2=CC=CC=C2)C=C1 |&1:3,6,r|
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
D472585
Product name
(αS,​γS)​-γ-​[[(1,​1-​Dimethylethoxy)​carbonyl]​amino]​-​α-​methyl-[1,​1''-​biphenyl]​-​4-​pentanoicAcid
Packaging
5mg
Price
$275
Updated
2021/12/16
Crysdot
Product number
CD21019729
Product name
(2S,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoicacid
Purity
97%
Packaging
10mg
Price
$416
Updated
2021/12/16
Crysdot
Product number
CD21019729
Product name
(2S,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoicacid
Purity
97%
Packaging
25mg
Price
$972
Updated
2021/12/16
Crysdot
Product number
CD21019729
Product name
(2S,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoicacid
Purity
97%
Packaging
50mg
Price
$1736
Updated
2021/12/16
Crysdot
Product number
CD21019729
Product name
(2S,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoicacid
Purity
97%
Packaging
5mg
Price
$228
Updated
2021/12/16
More
Less

(2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Chemical Properties,Usage,Production

Uses

(αS,γS)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1''-biphenyl]-4-pentanoic Acid is a useful synthetic intermediate.

(2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Suppliers

China 64 India 4 United States 4 Global 72
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
10193
Advantage
58
Adamas Reagent, Ltd.
Tel
400-6009262 15618770481
Fax
021-64823266
Email
yhx@titansci.com
Country
China
ProdList
14100
Advantage
59
Jiangsu Vcare PharmaTech Co., Ltd.
Tel
025-58741518 13327700685
Fax
+86-25-58744115
Email
sales@vcarepharmatech.com
Country
China
ProdList
283
Advantage
61
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5157
Advantage
50
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39999
Advantage
60
Changzhou Renaissance Chem Co. Ltd
Tel
86-519-86202821
Fax
Email： sales@rosewellchem.com
Country
China
ProdList
116
Advantage
56
Quality Control Solutions Ltd.
Tel
0755-66853366 13670046396
Fax
0755-28363542
Email
orders@qcsrm.com
Country
China
ProdList
18421
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939; 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
15781
Advantage
55
PharmaSea Pharmaceutical Tech.
Tel
010-52980412
Fax
010-52980412
Email
chemsales@pharmasea.com.cn
Country
China
ProdList
49
Advantage
58

1012341-52-4, (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acidRelated Search:

Sacubitril Impurity 21 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid LCZ696 (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate AHU-377 (heMicalciuM salt) Valsartan LCZ Impurity (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester LCZ696 interMediate (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoate (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid AHU-377

  • (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
  • LCZ 696 Impurity E
  • Sacubitril Impurity 2
  • LCZ706
  • (2S,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid
  • (αS,γS)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl-[1,1-biphenyl]-4-pentanoic Acid
  • Sacubitril Impurity E
  • LCZ696696-A-A
  • LCZ-696 Impurity 17
  • LCZ696(valsartan + sacubitril) impurity 21
  • LCZ696-20
  • 1,1'-Biphenyl]-4-pentanoic acid, γ-[[(1,1-dimethylethoxy)carbonyl]amino]-α-methyl-, (αS,γS)-
  • (αS,?γS)?-γ-?[[(1,?1-?Dimethylethoxy)?carbonyl]?amino]?-?α-?methyl-[1,?1'-?biphenyl]?-?4-?pentanoic Acid
  • impurity 21
  • LCZ696 impurities125
  • LCZ696 impuritiesE
  • LCZ-696 Impurity 17(S,S)
  • Valsartan Impurity45 （Sacubitril impurity 45）
  • Sacubitril Impurity FA
  • 1012341-52-4
  • LCZ696