ChemicalBook > CAS DataBase List > 4-Amino-7H-pyrrolo[2,3-d]pyrimidine

4-Amino-7H-pyrrolo[2,3-d]pyrimidine

Product Name
4-Amino-7H-pyrrolo[2,3-d]pyrimidine
CAS No.
1500-85-2
Chemical Name
4-Amino-7H-pyrrolo[2,3-d]pyrimidine
Synonyms
7-DEAZAADENINE;6-Amino-7-deazapurine;6-AMino-7-deazapurine 97%;4-Amino-7H-pyrrolo[2,3-d]...;4-Aminopyrrolo[2,3-d]Pyrimidin;4-AMINOPYRROLO[2,3-D]PYRIMIDINE;1H-Pyrrolo[2,3-d]pyrimidin-4-amin;7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE;3-d)pyrimidine,4-amino-7h-pyrrolo(;4-Amino-7H-pyrrolo[2,3-d]pyrimidine
CBNumber
CB6306218
Molecular Formula
C6H6N4
Formula Weight
134.14
MOL File
1500-85-2.mol
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4-Amino-7H-pyrrolo[2,3-d]pyrimidine Property

Melting point:
257-262℃
Boiling point:
318.3±45.0 °C(Predicted)
Density 
1.61±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
13.38±0.20(Predicted)
form 
Solid
color 
White to pale brown
Sensitive 
Moisture & Light Sensitive
InChIKey
PEHVGBZKEYRQSX-UHFFFAOYSA-N
CAS DataBase Reference
1500-85-2(CAS DataBase Reference)
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
2
RTECS 
UY8850000
HazardClass 
IRRITANT
PackingGroup 
Ⅲ
HS Code 
2933599590
Toxicity
mouse,LD50,intraperitoneal,300mg/kg (300mg/kg),Gann. Japanese Journal of Cancer Research. Vol. 56, Pg. 219, 1965.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
722332
Product name
6-Amino-7-deazapurine
Purity
97%
Packaging
1g
Price
$95.4
Updated
2024/03/01
Alfa Aesar
Product number
H66987
Product name
6-Amino-7-deazapurine, 97%
Packaging
1g
Price
$56.4
Updated
2021/12/16
Alfa Aesar
Product number
H66987
Product name
6-Amino-7-deazapurine, 97%
Packaging
5g
Price
$224
Updated
2021/12/16
Usbiological
Product number
270848
Product name
7-Deazaadenine
Packaging
1g
Price
$352
Updated
2021/12/16
TRC
Product number
A629278
Product name
4-Amino-7H-pyrrolo[2,3-d]pyrimidine
Packaging
50mg
Price
$45
Updated
2021/12/16
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4-Amino-7H-pyrrolo[2,3-d]pyrimidine Chemical Properties,Usage,Production

Synthesis

A mixture of 5-ethynylpyrimidine-4,6-diamine (300?mg, 2.24?mmol), Cs2CO3 (1.46?g, 4.47?mmol) and DMSO (4.00?ml) in a 10.00?ml microwave tube was irradiated at 100?W and 180?°C for 15?minutes. After this time, the reaction mixture was cooled to room temperature and poured into a separating funnel containing 100?ml water and 100?ml ethyl acetate. The aqueous layer was extracted with EtOAc (2×100?ml). The combined organic extracts were dried with MgSO4 and filtered through celite, and excess solvent was removed in vacuo. Purification by column chromatography (80?% EtOAc/hexane – 10?% MeOH/CH2Cl2) gave 7H-pyrrolo[2,3-d]pyrimidin-4-amine (4-Amino-7H-pyrrolo[2,3-d]pyrimidine) (0.15?g, 50?%) as an off-white solid[1].

References

[1] Dr. Tswene D. Seanego. “7H-Pyrrolo[2,3-d]pyrimidine-4-amines as Potential Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinases.” ChemMedChem 17 22 (2022).

4-Amino-7H-pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Amino-7H-pyrrolo[2,3-d]pyrimidine Suppliers

China 196 Europe 1 India 3 United Kingdom 6 United States 18 Global 224
Hefei Xiuhe Biotechnology Co. Ltd.
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0551-62887095 13856031416
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65854417@qq.com
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China
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SiChuang NanBu Honesty Technology Co., Ltd.
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0838-5675166 15883665058
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0838-5675535
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nbcxkj@126.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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ChemFuture PharmaTech (Jiangsu) Ltd
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5108538618
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86 510 85386988-8017
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suger.wang@chemfuture.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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Wuhan Chemwish Technology Co., Ltd
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86-027-67849912
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sales@chemwish.com
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China
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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sales@capotchem.com
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China
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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sales@jingyan-chemical.com
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China
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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0573-85285100
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isenchem@163.com
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China
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9510
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66
Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
Country
United States
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View Lastest Price from 4-Amino-7H-pyrrolo[2,3-d]pyrimidine manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4-Amino-7H-pyrrolo[2,3-d]pyrimidine 1500-85-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26
Dideu Industries Group Limited
Product
4-Amino-7H-pyrrolo[2,3-d]pyrimidine 1500-85-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-10
Career Henan Chemical Co
Product
4-Amino-7H-pyrrolo[2,3-d]pyrimidine 1500-85-2
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-03

1500-85-2, 4-Amino-7H-pyrrolo[2,3-d]pyrimidineRelated Search:

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