Br-PEG1-COOtBu
- Product Name
- Br-PEG1-COOtBu
- CAS No.
- 1393330-36-3
- Chemical Name
- Br-PEG1-COOtBu
- Synonyms
- Br-PEG1-COOtBu;CAS_1393330-36-3;Bromo-PEG1-C2-Boc;Br-PEG1-CH2CH2COOtBu;Bromo-PEG1-t-butyl ester;Bromo-PEG1-tert-butyl Ester;tert-Butyl 3-(2-bromoethoxy)propanoate;Propanoic acid, 3-(2-bromoethoxy)-, 1,1-dimethylethyl ester
- CBNumber
- CB63062438
- Molecular Formula
- C9H17BrO3
- Formula Weight
- 253.13
- MOL File
- 1393330-36-3.mol
Br-PEG1-COOtBu Property
- Boiling point:
- 285.0±15.0 °C(Predicted)
- Density
- 1.264±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DCM, Hexane
- form
- Liquid
- color
- Colorless to light yellow
- InChI
- InChI=1S/C9H17BrO3/c1-9(2,3)13-8(11)4-6-12-7-5-10/h4-7H2,1-3H3
- InChIKey
- KRGOEVTUVNSLIG-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)CCOCCBr
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P313Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B750705
- Product name
- Bromo-PEG1-t-butylEster
- Packaging
- 50mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- 8402DP
- Product name
- Bromo-PEG1-t-butylester
- Packaging
- 5g
- Price
- $2444
- Updated
- 2021/12/16
- Product number
- BP-20900
- Product name
- Bromo-PEG1-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- 8402DP
- Product name
- Bromo-PEG1-t-butylester
- Packaging
- 250mg
- Price
- $464
- Updated
- 2021/12/16
- Product number
- BIPG1347
- Product name
- Bromo-PEG1-t-butyl ester
- Packaging
- 250mg
- Price
- $546
- Updated
- 2021/12/16
Br-PEG1-COOtBu Chemical Properties,Usage,Production
Description
Bromo-PEG1-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Bromo-PEG1-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Br-PEG1-COOtBu Preparation Products And Raw materials
Raw materials
Preparation Products
Br-PEG1-COOtBu Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
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- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
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- Tel
- --
- Fax
- --
- sales@combi-blocks.com
- Country
- United States
- ProdList
- 6618
- Advantage
- 69
View Lastest Price from Br-PEG1-COOtBu manufacturers
- Product
- Br-PEG1-COOtBu 1393330-36-3
- Price
- US $0.00/g
- Min. Order
- 10g
- Purity
- >98.00%
- Supply Ability
- 10g
- Release date
- 2024-03-25
- Product
- Bromo-PEG1-t-butyl ester 1393330-36-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-21
- Product
- Bromo-PEG1-t-butyl ester 1393330-36-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-21