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Propargyl-PEG4-CH2CO2tBu

Product Name
Propargyl-PEG4-CH2CO2tBu
CAS No.
888010-02-4
Chemical Name
Propargyl-PEG4-CH2CO2tBu
Synonyms
Alkyne-PEG4-CH2COOtBu;Propargyl-PEG3-OCH2-Boc;PROPARGYL-PEG4-CH2COOTBU;Propargyl-PEG4-CH2CO2tBu;Propargyl-PEG3-CH2COOtBu;Propargyl-PEG3-t-butyl acetate;Propargyl-PEG4-CH2COOH t-Bu Ester;tert-butyl 3,6,9,12-tetraoxapentadec-14-ynoate;3,6,9,12-Tetraoxapentadec-14-ynoic acid, 1,1-dimethylethyl ester;tert-butyl-2-(2-{2-[2-(prop-2-ynyloxy)ethoxy]ethoxy}ethoxy)acetate
CBNumber
CB63062625
Molecular Formula
C15H26O6
Formula Weight
302.36
MOL File
888010-02-4.mol
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Propargyl-PEG4-CH2CO2tBu Property

Boiling point:
365.6±32.0 °C(Predicted)
Density 
1.046±0.06 g/cm3(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22300
Product name
Propargyl-PEG4-CH2CO2tBu
Purity
98%
Packaging
100mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-22300
Product name
Propargyl-PEG4-CH2CO2tBu
Purity
98%
Packaging
250mg
Price
$460
Updated
2021/12/16
Activate Scientific
Product number
AS107946
Product name
Propargyl-PEG3-CH2COOtBu
Purity
97%
Packaging
1g
Price
$464
Updated
2021/12/16
Apolloscientific
Product number
BIPG1732
Product name
Propargyl-PEG4-CH2CO2tBu
Packaging
100mg
Price
$546
Updated
2021/12/16
Acrotein
Product number
B-1486
Product name
Propargyl-PEG3-CH2COOtBu
Purity
97%
Packaging
0.5g
Price
$220
Updated
2021/12/16
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Propargyl-PEG4-CH2CO2tBu Chemical Properties,Usage,Production

Description

Propargyl-PEG4-CH2CO2tBu is a PEG reagent that can reacts with azide compounds or biomolecules under the catalyzation of copper. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-OCH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG4-CH2CO2tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG4-CH2CO2tBu Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

888010-02-4, Propargyl-PEG4-CH2CO2tBuRelated Search:


  • Propargyl-PEG4-CH2CO2tBu
  • Alkyne-PEG4-CH2COOtBu
  • PROPARGYL-PEG4-CH2COOTBU
  • tert-butyl-2-(2-{2-[2-(prop-2-ynyloxy)ethoxy]ethoxy}ethoxy)acetate
  • Propargyl-PEG3-t-butyl acetate
  • Propargyl-PEG3-CH2COOtBu
  • Propargyl-PEG3-OCH2-Boc
  • tert-butyl 3,6,9,12-tetraoxapentadec-14-ynoate
  • Propargyl-PEG4-CH2COOH t-Bu Ester
  • Propargyl-PEG3-CH2COOtBu/3,6,9,12-Tetraoxapentadec-14-ynoic acid, 1,1-dimethylethyl ester
  • 3,6,9,12-Tetraoxapentadec-14-ynoic acid, 1,1-dimethylethyl ester
  • 888010-02-4
  • peg