2-HYDROXY-5-METHYLBENZOPHENONE
- Product Name
- 2-HYDROXY-5-METHYLBENZOPHENONE
- CAS No.
- 1470-57-1
- Chemical Name
- 2-HYDROXY-5-METHYLBENZOPHENONE
- Synonyms
- RARECHEM FH 1L 0064;2-Benzoyl-4-methylphenol;5-Methyl-2-hydroxybenzophenone;2-HYDROXY-5-METHYLBENZOPHENONE;2- Hyroxy-5-methyl benzophenone;2'-HYDROXY 5'-METHYL BENZOPHENONE;Benzophenone, 2-hydroxy-5-methyl-;2-Hydroxy-5-methylbenzophenone>2-Hydroxy-5-methylbenzophenone 99%;2-Hydroxy-5-methylbenzophenone,99%
- CBNumber
- CB6306465
- Molecular Formula
- C14H12O2
- Formula Weight
- 212.24
- MOL File
- 1470-57-1.mol
2-HYDROXY-5-METHYLBENZOPHENONE Property
- Melting point:
- 83-85 °C (lit.)
- Boiling point:
- 312.08°C (rough estimate)
- Density
- 1.1035 (rough estimate)
- refractive index
- 1.6000 (estimate)
- pka
- 8.24±0.43(Predicted)
- form
- powder to crystal
- color
- Light orange to Yellow to Green
- CAS DataBase Reference
- 1470-57-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H38608
- Product name
- 2-Hydroxy-5-methylbenzophenone
- Purity
- 99%
- Packaging
- 5g
- Price
- $63.8
- Updated
- 2023/06/20
- Product number
- H1008
- Product name
- 2-Hydroxy-5-methylbenzophenone
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $79
- Updated
- 2024/03/01
- Product number
- H1008
- Product name
- 2-Hydroxy-5-methylbenzophenone
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $230
- Updated
- 2024/03/01
- Product number
- H946865
- Product name
- 2-Hydroxy-5-methylbenzophenone
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- H946865
- Product name
- 2-Hydroxy-5-methylbenzophenone
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
2-HYDROXY-5-METHYLBENZOPHENONE Chemical Properties,Usage,Production
Chemical Properties
yellow crystalline powder
Uses
2-?Hydroxy-?5-?methylbenzophenone is a general reagent used in the synthesis of anti-bacterial and anti-fungal agents.
Preparation
Preparation by condensation of benzotrichloride with p-cresol,
? in the presence of aluminium chloride in carbon disulfide for 2 h (75%). The 6,12-diphenyl-2,8-dimethyl-6,12-epoxy-6H,12H-dibenzo[b,f] dioxocin, an intermediate compound, was also formed under these conditions (29%). This “dioxocin”, by hydrolysis with concentrated sulfuric acid at r.t., gave the expected ketone (91%);
? in the presence of aqueous sodium hydroxide in a water bath for 4 h (33%) or in 32–40% aqueous sodium hydroxide at 70–80° (67%).
Synthesis Reference(s)
The Journal of Organic Chemistry, 38, p. 1924, 1973 DOI: 10.1021/jo00950a030