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BENFLUOREX HYDROCHLORIDE

Product Name
BENFLUOREX HYDROCHLORIDE
CAS No.
23642-66-2
Chemical Name
BENFLUOREX HYDROCHLORIDE
Synonyms
Balans;mediator;LT00134683;Lipophoral;Einecs 245-801-8;LABOTEST-BB LT00134683;BENFLUOREX HYDROCHLORIDE;2-(alpha-Methyl-3-(trifluoromethyl)phenylethylamino)ethyl benzoat;2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)-ethanobenzoate(est;2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-ethanobenzoate(est
CBNumber
CB6306571
Molecular Formula
C19H21ClF3NO2
Formula Weight
387.82
MOL File
23642-66-2.mol
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BENFLUOREX HYDROCHLORIDE Property

Melting point:
158-159?C
storage temp. 
Refrigerator
solubility 
Chlorform (Slightly), Methanol (Slightly), Water (Slightly)
color 
White
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Safety

Hazard Codes 
Xi
WGK Germany 
2
RTECS 
KL8275000
Hazard Note 
Irritant
HS Code 
2916399090
Toxicity
LD50 intraperitoneal in mouse: 108mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B7522
Product name
Benfluorex hydrochloride
Purity
analytical standard
Packaging
5g
Price
$82.4
Updated
2024/03/01
TRC
Product number
B135000
Product name
Benfluorex hydrochloride
Packaging
5mg
Price
$95
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001607
Product name
BENFLUOREX HYDROCHLORIDE
Purity
95.00%
Packaging
25MG
Price
$476.7
Updated
2021/12/16
Crysdot
Product number
CD33000379
Product name
Benfluorex hydrochloride
Purity
98+%
Packaging
100mg
Price
$50
Updated
2021/12/16
AHH
Product number
MT-47373
Product name
Benfluorex hydrochloride
Purity
98%
Packaging
100g
Price
$310
Updated
2021/12/16
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BENFLUOREX HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Mediator,Servier,France,1976

Uses

Hypolipedimic;Increase of glucose penetration and use by cells

Uses

BENFLUOREX HYDROCHLORIDE can be used as an antihyperlipoproteinemic therapeutic and increase of glucose penetration and use by cells.

Manufacturing Process

To a solution of 24.7 parts of 1-(m-trifluoromethylphenyl)-2-(β- hydroxyethyl)amino propane in 140 parts of anhydrous benzene, there were added successively 15 parts of 4.7N hydrochloric ether and a solution of 14 parts of benzoyl chloride in 24 parts of anhydrous benzene. The addition required 10 minutes, the reaction mixture was then refluxed for 8 hours.
The solid product was collected by filtration and after recrystallization from 230 parts of ethyl acetate, there were obtained 15 parts of 1-(mtrifluoromethylphenyl)- 2-(β-benzoyloxyethyl)amino propane hydrochloride melting at 161°C.
10 parts hydrochloride are put in suspension in 100 parts of water, 80 parts ether are added, then 10 parts of a concentrated solution of ammonium hydroxide. The mixture is stirred a few minutes until the salt is dissolved, then the ethered solution is poured off and dried. After the ether is eliminated, 9 parts of 1-(m-trifluoromethylphenyl)-2-(β- benzoyloxyethyl)amino propane are obtained; the base is a colorless oil.

Therapeutic Function

Antihyperlipidemic, Cardiovascular

BENFLUOREX HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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BENFLUOREX HYDROCHLORIDE Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Suzhou Kaiyuan Minsheng Sci&Tech Corp. Ltd.
Tel
0512-62889106
Fax
0512-62889106
Email
business@minshengpharm.com
Country
China
ProdList
110
Advantage
66
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3421
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shenzhen Newcore Chemical Technology Co., Ltd.
Tel
13612807752
Email
ncchemical@163.com
Country
China
ProdList
290
Advantage
55
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4662
Advantage
60
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17997
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
20512
Advantage
60
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View Lastest Price from BENFLUOREX HYDROCHLORIDE manufacturers

Wuhan Monad Medicine Tech Co.,LTD
Product
BENFLUOREX HYDROCHLORIDE 23642-66-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99.99%
Supply Ability
20 tons/month
Release date
2020-12-24
Career Henan Chemical Co
Product
2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethyl benzoate hydrochloride 23642-66-2
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

23642-66-2, BENFLUOREX HYDROCHLORIDERelated Search:


  • 2-((1-methyl-2-(3-(trifluoromethyl)phenyl)ethyl)amino)-ethanobenzoate(est
  • 2-((alpha-methyl-m-(trifluoromethyl)phenethyl)amino)-ethanobenzoate(est
  • 2-((1-(3-(trifluoromethyl)phenyl)propan-2-yl)amino)ethyl benzoate hydrochloride
  • mediator
  • BENFLUOREX HYDROCHLORIDE
  • 2-[[1-METHYL-2-[3-(TRIFLUOROMETHYL)-PHENYL]ETHYL]AMINO]ETHANOL BENZOATE (ESTER) HCL
  • 2-[[1-METHYL-2[3-(TRIFLUOROMETHYL)-PHENYL]ETHYL]AMINO]ETHANOL BENZOATE ESTER HYDROCHLORIDE
  • 2-((1-METHYL-2-[3-(TRIFLUOROMETHYL)PHENYL]ETHYL)AMINO)ETHYL BENZOATE HYDROCHLORIDE
  • LABOTEST-BB LT00134683
  • 2-[[1-Methyl-2-[3-(trifluoroMethyl)-phenyl]ethyl]aMino]ethanol Benzoate HCl Salt
  • 2-(alpha-Methyl-3-(trifluoromethyl)phenylethylamino)ethyl benzoat
  • Balans
  • Einecs 245-801-8
  • 2-({1-[3-(Trifluoromethyl)phenyl]prop-2-yl}amino)ethyl benzoate hydrochloride
  • 2-[[1-Methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]ethanol benzoate hydrochloride
  • LT00134683
  • Lipophoral
  • Ethanol,2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, 1-benzoate,hydrochloride (1:1)
  • JP992,JP 992,Inhibitor,Benfluorex,Benfluorex hydrochloride,JP-992,inhibit
  • 23642-66-2
  • C19H21ClF3NO2
  • C19H20F3NO2HCl
  • C19H20F3NO2ClH
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals