Synthesis Chemical Properties Uses
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1,3-Difluorobenzene

Synthesis Chemical Properties Uses
Product Name
1,3-Difluorobenzene
CAS No.
372-18-9
Chemical Name
1,3-Difluorobenzene
Synonyms
M-DIFLUOROBENZENE;1,3-DifL;DIFLOUROBENZENE;m-difluoro-benzen;m-Difluro Benzene;1,3-Difluorbenzol;3-DifluoroBenzene;1?-Difluorobenzene;1,3-DIFLUOROBENZEN;Benzene,m-difluoro-
CBNumber
CB9853566
Molecular Formula
C6H4F2
Formula Weight
114.09
MOL File
372-18-9.mol
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1,3-Difluorobenzene Property

Melting point:
-59 °C
Boiling point:
83 °C
Density 
1.163 g/mL at 25 °C(lit.)
vapor pressure 
11.034-19.924kPa at 20-38.2℃
refractive index 
n20/D 1.438(lit.)
Flash point:
36 °F
storage temp. 
Flammables area
solubility 
1.1g/l
form 
Liquid
Specific Gravity
1.163
color 
Clear colorless to yellow
Water Solubility 
insoluble
BRN 
1904537
Dielectric constant
5.2400000000000002
LogP
2.21-2.52 at 25℃ and pH6.5
CAS DataBase Reference
372-18-9(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, 1,3-difluoro-(372-18-9)
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Safety

Hazard Codes 
F,Xn
Risk Statements 
11-20-2017/11/20
Safety Statements 
7-16-29-33-7/9
RIDADR 
UN 1993 3/PG 2
WGK Germany 
1
RTECS 
CZ5652000
Hazard Note 
Highly Flammable
HazardClass 
3
PackingGroup 
II
HS Code 
29036990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D102008
Product name
1,3-Difluorobenzene
Purity
≥99%
Packaging
10g
Price
$78.6
Updated
2024/03/01
Sigma-Aldrich
Product number
D102008
Product name
1,3-Difluorobenzene
Purity
≥99%
Packaging
100g
Price
$144
Updated
2024/03/01
TCI Chemical
Product number
D1626
Product name
1,3-Difluorobenzene
Purity
>98.0%(GC)
Packaging
25g
Price
$66
Updated
2024/03/01
TCI Chemical
Product number
D1626
Product name
1,3-Difluorobenzene
Purity
>98.0%(GC)
Packaging
500g
Price
$457
Updated
2024/03/01
Alfa Aesar
Product number
A14387
Product name
1,3-Difluorobenzene, 99%
Packaging
10g
Price
$54.65
Updated
2024/03/01
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1,3-Difluorobenzene Chemical Properties,Usage,Production

Synthesis

Higher yields were observed when CsF and HF were reacted with 1,3-dichlorobenzene, which gave I ,3-difluorobenzene.

Chemical Properties

1,3-Difluorobenzene (C6H4F2, CAS registry No. 372-18-9) is also named as m-difluorobenzene, which is a clear colorless to yellowish liquid. Its melting point is -59 °C, boiling point is 83 °C and flash point is 2 oC. It is insoluble in water and stable under normal temperatures and pressures. It is toxic and flammable. It will produce toxic fluoride gas by heat.

Uses

1,3-Difluorobenzene has been extensively used in the synthesis of pharmaceutical and pesticide intermediate. For example, it can be used for the synthesis of fluorinated medicine such as Fluconazole, etc. and pesticide (Flucycloxuron, Diflubenzuro, etc.). It can also be used to synthesize liquid crystal materials.

Chemical Properties

CLEAR COLORLESS TO YELLOWISH LIQUID

Uses

It is used in the laser induced fluorencence matrix study of 1,3-difluorobenzene radical cation. It is also used synthesis of 1,2,3-triazole containing fluconazole analogues.

Definition

ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 3.

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1,3-Difluorobenzene Suppliers

Zhejiang Xieshi New Materials Co., Ltd.
Tel
0575-82399190 15605850595
Email
15605850595@139.com
Country
China
ProdList
1
Advantage
58
Shanghai Kaisai Chemical Co., Ltd
Tel
021-33516722 13701817765
Fax
021-33516776
Email
kaisaichem@163.com
Country
China
ProdList
4752
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
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View Lastest Price from 1,3-Difluorobenzene manufacturers

Henan Fengda Chemical Co., Ltd
Product
1,3-Difluorobenzene 372-18-9
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-25
Hebei Guanlang Biotechnology Co,.LTD
Product
1,3-Difluorobenzene 372-18-9
Price
US $10.60/KG
Min. Order
1KG
Purity
98%
Supply Ability
5000kg
Release date
2021-07-07
Hebei Guanlang Biotechnology Co., Ltd.
Product
1,3-Difluorobenzene 372-18-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-02-16

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