1,3-Difluorobenzene
Synthesis Chemical Properties Uses- Product Name
- 1,3-Difluorobenzene
- CAS No.
- 372-18-9
- Chemical Name
- 1,3-Difluorobenzene
- Synonyms
- M-DIFLUOROBENZENE;1,3-DFB;1,3-DifL;DIFLOUROBENZENE;m-difluoro-benzen;m-Difluro Benzene;1,3-Difluorbenzol;3-DifluoroBenzene;1?-Difluorobenzene;1,3-DIFLUOROBENZEN
- CBNumber
- CB9853566
- Molecular Formula
- C6H4F2
- Formula Weight
- 114.09
- MOL File
- 372-18-9.mol
1,3-Difluorobenzene Property
- Melting point:
- -59 °C
- Boiling point:
- 83 °C
- Density
- 1.163 g/mL at 25 °C(lit.)
- vapor pressure
- 11.034-19.924kPa at 20-38.2℃
- refractive index
- n20/D 1.438(lit.)
- Flash point:
- 36 °F
- storage temp.
- Flammables area
- solubility
- 1.1g/l
- form
- Liquid
- Specific Gravity
- 1.163
- color
- Clear colorless to yellow
- Water Solubility
- insoluble
- BRN
- 1904537
- Henry's Law Constant
- 3.6×10-3 mol/(m3Pa) at 25℃, Gharagheizi et al. (2012)
- Dielectric constant
- 5.2400000000000002
- InChI
- 1S/C6H4F2/c7-5-2-1-3-6(8)4-5/h1-4H
- InChIKey
- UEMGWPRHOOEKTA-UHFFFAOYSA-N
- SMILES
- Fc1cccc(F)c1
- LogP
- 2.21-2.52 at 25℃ and pH6.5
- CAS DataBase Reference
- 372-18-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzene, 1,3-difluoro-(372-18-9)
Safety
- Hazard Codes
- F,Xn
- Risk Statements
- 11-20-2017/11/20
- Safety Statements
- 7-16-29-33-7/9
- RIDADR
- UN 1993 3/PG 2
- WGK Germany
- 1
- RTECS
- CZ5652000
- Hazard Note
- Highly Flammable
- HazardClass
- 3
- PackingGroup
- II
- HS Code
- 29036990
- Storage Class
- 3 - Flammable liquids
- Hazard Classifications
- Flam. Liq. 2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H333May be harmful if inhaled
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P312IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D102008
- Product name
- 1,3-Difluorobenzene
- Purity
- ≥99%
- Packaging
- 10g
- Price
- $86.3
- Updated
- 2026/04/30
- Product number
- D102008
- Product name
- 1,3-Difluorobenzene
- Purity
- ≥99%
- Packaging
- 100g
- Price
- $157
- Updated
- 2026/04/30
- Product number
- D1626
- Product name
- 1,3-Difluorobenzene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $74
- Updated
- 2026/04/30
- Product number
- D1626
- Product name
- 1,3-Difluorobenzene
- Purity
- >98.0%(GC)
- Packaging
- 500g
- Price
- $509
- Updated
- 2026/04/30
- Product number
- 09-0001
- Product name
- 1,3-Difluorobenzene, min. 99%
- Purity
- min.99%
- Packaging
- 25g
- Price
- $44
- Updated
- 2026/04/30
1,3-Difluorobenzene Chemical Properties,Usage,Production
Synthesis
Higher yields were observed when CsF and HF were reacted with 1,3-dichlorobenzene,
which gave I ,3-difluorobenzene.
Chemical Properties
1,3-Difluorobenzene (C6H4F2, CAS registry No. 372-18-9) is also named as m-difluorobenzene, which is a clear colorless to yellowish liquid. Its melting point is -59 °C, boiling point is 83 °C and flash point is 2 oC. It is insoluble in water and stable under normal temperatures and pressures. It is toxic and flammable. It will produce toxic fluoride gas by heat.
Uses
1,3-Difluorobenzene has been extensively used in the synthesis of pharmaceutical and pesticide intermediate. For example, it can be used for the synthesis of fluorinated medicine such as Fluconazole, etc. and pesticide (Flucycloxuron, Diflubenzuro, etc.). It can also be used to synthesize liquid crystal materials.
Chemical Properties
CLEAR COLORLESS TO YELLOWISH LIQUID
Uses
It is used in the laser induced fluorencence matrix study of 1,3-difluorobenzene radical cation. It is also used synthesis of 1,2,3-triazole containing fluconazole analogues.
Definition
ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 3.
1,3-Difluorobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,3-Difluorobenzene manufacturers
- Product
- 1,3-Difluorobenzene 372-18-9
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-28
- Product
- 1,3-Difluorobenzene 372-18-9
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-09-13
- Product
- 1,3-Difluorobenzene 372-18-9
- Price
- US $10.60/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 5000kg
- Release date
- 2024-08-21