2,3-Difluorobenzoic acid
- Product Name
- 2,3-Difluorobenzoic acid
- CAS No.
- 4519-39-5
- Chemical Name
- 2,3-Difluorobenzoic acid
- Synonyms
- BUTTPARK 45\01-40;CHEMPACIFIC 39931;2,3-Difluorobenzoic;RARECHEM AL BO 0251;TIMTEC-BB SBB006679;3-Difluorobenzoic acid;2,3-DIFLUOROBENZOIC ACID;2,3-DIFLUOROBENZONIC ACID;2,3-DifluorobenzoicAcid>2,3-Difluorobenzoicacid,98%
- CBNumber
- CB1216459
- Molecular Formula
- C7H4F2O2
- Formula Weight
- 158.1
- MOL File
- 4519-39-5.mol
2,3-Difluorobenzoic acid Property
- Melting point:
- 163-165 °C (lit.)
- Boiling point:
- 248.1±20.0 °C(Predicted)
- Density
- 1.3486 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 2.93±0.10(Predicted)
- color
- White to Almost white
- Water Solubility
- slightly soluble
- BRN
- 2640781
- InChI
- InChI=1S/C7H4F2O2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,(H,10,11)
- InChIKey
- JLZVIWSFUPLSOR-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=CC(F)=C1F
- CAS DataBase Reference
- 4519-39-5(CAS DataBase Reference)
- EPA Substance Registry System
- Benzoic acid, 2,3-difluoro- (4519-39-5)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-37/38-36
- Safety Statements
- 26-37/39
- WGK Germany
- 3
- TSCA
- TSCA listed
- HazardClass
- IRRITANT
- HS Code
- 29163990
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 263516
- Product name
- 2,3-Difluorobenzoic acid
- Purity
- 98%
- Packaging
- 10g
- Price
- $85
- Updated
- 2025/07/31
- Product number
- 263516
- Product name
- 2,3-Difluorobenzoic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $28.9
- Updated
- 2023/06/20
- Product number
- D2058
- Product name
- 2,3-Difluorobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $73
- Updated
- 2025/07/31
- Product number
- D2058
- Product name
- 2,3-Difluorobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $278
- Updated
- 2025/07/31
- Product number
- D445590
- Product name
- 2,3-Difluorobenzoic acid
- Packaging
- 25g
- Price
- $305
- Updated
- 2021/12/16
2,3-Difluorobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
white to off-white powder
Uses
2,3-Difluorobenzoic acid has been used as a tracer for determining the extent of recovery of materials injected into oil wells.
General Description
2,3-Difluorobenzoic acid forms dimers that are stabilized by hydrogen bonds. It is used in pharmaceuticals, pesticides, and liquid crystal material intermediates.
Synthesis
124-38-9
126163-64-2
4519-39-5
Carbon dioxide gas was passed into a reaction solution containing lithium 2,3-difluorobenzene (CAS:126163-64-2) at a temperature of -65 to -60 °C, ensuring that the molar ratio of carbon dioxide to lithium 2,3-difluorobenzene was 1.5:1. The reaction was maintained at this temperature for 4 hours. Upon completion of the reaction, water was added for hydrolysis at a mass ratio of water to reaction solution of 1.5:1 and the hydrolysis temperature was controlled at 15-20 °C. Subsequently, the organic solvent was removed by heating distillation and the reaction mixture was concentrated. The temperature was adjusted to 20-22 °C and the reaction mixture was acidified with a 10% hydrochloric acid solution with a molar ratio of hydrochloric acid to lithium 2,3-difluorobenzene of 2:1. After acidification, the reaction was kept for 3 hours. The reaction mixture was cooled to 0°C and the crystals formed were collected by diafiltration. The crystals were washed with a buffer solution of pH=2 and subsequently dried to give 2,3-difluorobenzoic acid. The purity of the final product was 99.5% and the yield was 90%.
References
[1] Patent: CN108658759, 2018, A. Location in patent: Paragraph 0032; 0037
2,3-Difluorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,3-Difluorobenzoic acid manufacturers
- Product
- 2,3-Difluorobenzoic acid 4519-39-5
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 1000kg
- Release date
- 2025-09-09
- Product
- 2,3-Difluorobenzoic acid 4519-39-5
- Price
- US $9.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-29
- Product
- 2,3-difluorobenzoic acid 4519-39-5
- Price
- US $290.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 300MT/year
- Release date
- 2019-12-24