ChemicalBook > CAS DataBase List > 2,3-Difluorobenzoic acid

2,3-Difluorobenzoic acid

Product Name: 2,3-Difluorobenzoic acid
CAS No.: 4519-39-5
Chemical Name: 2,3-Difluorobenzoic acid
Synonyms: BUTTPARK 45\01-40;CHEMPACIFIC 39931;2,3-Difluorobenzoic;RARECHEM AL BO 0251;TIMTEC-BB SBB006679;3-Difluorobenzoic acid;2,3-DIFLUOROBENZOIC ACID;2,3-DIFLUOROBENZONIC ACID;2,3-DifluorobenzoicAcid>2,3-Difluorobenzoicacid,98%
CBNumber: CB1216459
Molecular Formula: C7H4F2O2
Formula Weight: 158.1
MOL File: 4519-39-5.mol

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2,3-Difluorobenzoic acid Property

Melting point:: 163-165 °C (lit.)
Boiling point:: 248.1±20.0 °C(Predicted)
Density: 1.3486 (estimate)
storage temp.: Sealed in dry,Room Temperature
form: powder to crystal
pka: 2.93±0.10(Predicted)
color: White to Almost white
Water Solubility: slightly soluble
BRN: 2640781
InChI: InChI=1S/C7H4F2O2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,(H,10,11)
InChIKey: JLZVIWSFUPLSOR-UHFFFAOYSA-N
SMILES: C(O)(=O)C1=CC=CC(F)=C1F
CAS DataBase Reference: 4519-39-5(CAS DataBase Reference)
EPA Substance Registry System: Benzoic acid, 2,3-difluoro- (4519-39-5)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-37/38-36
Safety Statements: 26-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29163990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 263516
Product name: 2,3-Difluorobenzoic acid
Purity: 98%
Packaging: 10g
Price: $85
Updated: 2025/07/31

Sigma-Aldrich

Product number: 263516
Product name: 2,3-Difluorobenzoic acid
Purity: 98%
Packaging: 1g
Price: $28.9
Updated: 2023/06/20

TCI Chemical

Product number: D2058
Product name: 2,3-Difluorobenzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $73
Updated: 2025/07/31

TCI Chemical

Product number: D2058
Product name: 2,3-Difluorobenzoic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $278
Updated: 2025/07/31

TRC

Product number: D445590
Product name: 2,3-Difluorobenzoic acid
Packaging: 2.5g
Price: $115
Updated: 2021/12/16

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2,3-Difluorobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white powder

Uses

2,3-Difluorobenzoic acid has been used as a tracer for determining the extent of recovery of materials injected into oil wells.

General Description

2,3-Difluorobenzoic acid forms dimers that are stabilized by hydrogen bonds. It is used in pharmaceuticals, pesticides, and liquid crystal material intermediates.

Synthesis

124-38-9

126163-64-2

4519-39-5

Carbon dioxide gas was passed into a reaction solution containing lithium 2,3-difluorobenzene (CAS:126163-64-2) at a temperature of -65 to -60 °C, ensuring that the molar ratio of carbon dioxide to lithium 2,3-difluorobenzene was 1.5:1. The reaction was maintained at this temperature for 4 hours. Upon completion of the reaction, water was added for hydrolysis at a mass ratio of water to reaction solution of 1.5:1 and the hydrolysis temperature was controlled at 15-20 °C. Subsequently, the organic solvent was removed by heating distillation and the reaction mixture was concentrated. The temperature was adjusted to 20-22 °C and the reaction mixture was acidified with a 10% hydrochloric acid solution with a molar ratio of hydrochloric acid to lithium 2,3-difluorobenzene of 2:1. After acidification, the reaction was kept for 3 hours. The reaction mixture was cooled to 0°C and the crystals formed were collected by diafiltration. The crystals were washed with a buffer solution of pH=2 and subsequently dried to give 2,3-difluorobenzoic acid. The purity of the final product was 99.5% and the yield was 90%.

References

[1] Patent: CN108658759, 2018, A. Location in patent: Paragraph 0032; 0037

2,3-Difluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-Difluorobenzoic acid Suppliers

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View Lastest Price from 2,3-Difluorobenzoic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2,3-Difluorobenzoic acid 4519-39-5
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 1000kg
Release date: 2025-09-09

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2,3-Difluorobenzoic acid 4519-39-5
Price: US $9.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

Speranza Chemical Co., Ltd.

Product: 2,3-difluorobenzoic acid 4519-39-5
Price: US $290.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 300MT/year
Release date: 2019-12-24

4519-39-5, 2,3-Difluorobenzoic acidRelated Search:

Folic acid 4-Fluorobenzoic acid Isophthalic acid 1,3-Difluorobenzene Bis(2-ethylhexyl) phthalate Potassium hydrogen phthalate Phthalic acid Ethyl 2-(Chlorosulfonyl)acetate 1,2-Difluorobenzene Pentafluorobenzoic acid Citric acid Ascoric Acid 2,3,5,6-Tetrafluorobenzoic acid 4-AMINO-2,3,5,6-TETRAFLUOROBENZOIC ACID 2,3,5-TRIFLUOROBENZOIC ACID 2,3,6-TRIFLUOROBENZOIC ACID 2,3,4-Trifluorobenzoic acid 3,4-Difluorobenzoic acid 98%

2,3-DIFLUOROBENZOIC ACID

CHEMPACIFIC 39931

BUTTPARK 45\01-40

TIMTEC-BB SBB006679

RARECHEM AL BO 0251

2,3-Difluorobenzoic

2,3-Difluorobenzoic acid 98%

2,3-DIFLUOROBENZONIC ACID

2,3-Difluorobenzoicacid,98%

3-Carboxy-1,2-difluorobenzene

3-Difluorobenzoic acid

2,3-Difluorobenzoic acid, 98% 10GR

2,3-Difluorobenzoic acid, 98% 1GR

2,3- twofluoro benzoic acid

2,3-DifluorobenzoicAcid&gt

Benzoic acid, 2,3-difluoro-

(S)-2-(Cyclohexylmethyl)succinicacid-6-methyl ester

4519-39-5

ARYL ACID

Organic Building Blocks

Building Blocks

Carbonyl Compounds

Carboxylic Acids

Pyrroles

Carbonyl Compounds

Carboxylic Acids

Fluorobenzene

Miscellaneous

Fluorine series

Benzoic acid

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Aromatic compound

Fluorin-contained Benzoic acid series

john's