ChemicalBook > CAS DataBase List > 1,3-Difluorobenzene

1,3-Difluorobenzene

Synthesis Chemical Properties Uses

Product Name: 1,3-Difluorobenzene
CAS No.: 372-18-9
Chemical Name: 1,3-Difluorobenzene
Synonyms: M-DIFLUOROBENZENE;1,3-DFB;1,3-DifL;DIFLOUROBENZENE;m-difluoro-benzen;m-Difluro Benzene;1,3-Difluorbenzol;3-DifluoroBenzene;1?-Difluorobenzene;1,3-DIFLUOROBENZEN
CBNumber: CB9853566
Molecular Formula: C6H4F2
Formula Weight: 114.09
MOL File: 372-18-9.mol

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1,3-Difluorobenzene Property

Melting point:: -59 °C
Boiling point:: 83 °C
Density: 1.163 g/mL at 25 °C(lit.)
vapor pressure: 11.034-19.924kPa at 20-38.2℃
refractive index: n20/D 1.438(lit.)
Flash point:: 36 °F
storage temp.: Flammables area
solubility: 1.1g/l
form: Liquid
Specific Gravity: 1.163
color: Clear colorless to yellow
Water Solubility: insoluble
BRN: 1904537
Dielectric constant: 5.2400000000000002
LogP: 2.21-2.52 at 25℃ and pH6.5
CAS DataBase Reference: 372-18-9(CAS DataBase Reference)
NIST Chemistry Reference: Benzene, 1,3-difluoro-(372-18-9)

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Safety

Hazard Codes: F,Xn
Risk Statements: 11-20-2017/11/20
Safety Statements: 7-16-29-33-7/9
RIDADR: UN 1993 3/PG 2
WGK Germany: 1
RTECS: CZ5652000
Hazard Note: Highly Flammable
HazardClass: 3
PackingGroup: II
HS Code: 29036990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H225Highly Flammable liquid and vapour
Precautionary statements: P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D102008
Product name: 1,3-Difluorobenzene
Purity: ≥99%
Packaging: 10g
Price: $75.17
Updated: 2025/07/31

Sigma-Aldrich

Product number: D102008
Product name: 1,3-Difluorobenzene
Purity: ≥99%
Packaging: 100g
Price: $137.34
Updated: 2025/07/31

TCI Chemical

Product number: D1626
Product name: 1,3-Difluorobenzene
Purity: >98.0%(GC)
Packaging: 25g
Price: $66
Updated: 2025/07/31

TCI Chemical

Product number: D1626
Product name: 1,3-Difluorobenzene
Purity: >98.0%(GC)
Packaging: 500g
Price: $457
Updated: 2025/07/31

TRC

Product number: D447510
Product name: 1,3-Difluorobenzene
Packaging: 100g
Price: $305
Updated: 2021/12/16

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1,3-Difluorobenzene Chemical Properties,Usage,Production

Synthesis

Higher yields were observed when CsF and HF were reacted with 1,3-dichlorobenzene, which gave I ,3-difluorobenzene.

Chemical Properties

1,3-Difluorobenzene (C6H4F2, CAS registry No. 372-18-9) is also named as m-difluorobenzene, which is a clear colorless to yellowish liquid. Its melting point is -59 °C, boiling point is 83 °C and flash point is 2 oC. It is insoluble in water and stable under normal temperatures and pressures. It is toxic and flammable. It will produce toxic fluoride gas by heat.

Uses

1,3-Difluorobenzene has been extensively used in the synthesis of pharmaceutical and pesticide intermediate. For example, it can be used for the synthesis of fluorinated medicine such as Fluconazole, etc. and pesticide (Flucycloxuron, Diflubenzuro, etc.). It can also be used to synthesize liquid crystal materials.

Chemical Properties

CLEAR COLORLESS TO YELLOWISH LIQUID

Uses

It is used in the laser induced fluorencence matrix study of 1,3-difluorobenzene radical cation. It is also used synthesis of 1,2,3-triazole containing fluconazole analogues.

Definition

ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 3.

1,3-Difluorobenzene Preparation Products And Raw materials

Raw materials

Sodium nitrite Fluoroboric acid Hydrochloric acid m-Phenylenediamine 3-Nitroaniline

Preparation Products

2,4-Difluoronitrobenzene 2,6-Difluorophenol 1-Bromo-2,4-difluorobenzene Fluconazole 6-Fluoro-3-(4-piperidinyl)-1,2-benzisoxazole Risperidone

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View Lastest Price from 1,3-Difluorobenzene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1,3-Difluorobenzene 372-18-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-28

Qingdao RENAS Polymer Material Co., Ltd.

Product: 1,3-Difluorobenzene 372-18-9
Price: US $0.00/kg
Min. Order: 20kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-09-13

Hebei Chuanghai Biotechnology Co,.LTD

Product: 1,3-Difluorobenzene 372-18-9
Price: US $10.60/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 5000kg
Release date: 2024-08-21

372-18-9, 1,3-Difluorobenzene Related Search:

2,6-Difluorophenol 4-Fluorobenzaldehyde α,α-Difluorophenylacetic acid Florfenicol 3,4-Difluorobenzonitrile 2,6-Difluorobenzamide 2,3-Difluorobenzoic acid Transfluthrin 2,3-Difluorophenol 2,6-Difluorobenzoic acid 2,6-Difluorobenzaldehyde 2,6-Difluorobenzonitrile 2-Difluorobenzene,1,2-Difluorobenzene 98%,1,2-Difluorobenzene,98+%,o-Difluorobenzene,99% Pentafluorobenzene DECAFLUOROBENZHYDROL 2',3',4',5',6'-PENTAFLUOROACETOPHENONE 2,3,4,5,6-PENTAFLUOROBENZOPHENONE DIPHENYL(PENTAFLUOROPHENYL)PHOSPHINE

1,3-difluroethylene

Benzene, m-difluoro-

benzene,1,3-difluoro-

Benzene,m-difluoro-

Between two fluorine benzene

1,3-DifL

Difluoro-1,3-benzene

m-difluoro-benzen

meta-Difluorobenzene

M-DIFLUOROBENZENE

1?-Difluorobenzene

m-Difluro Benzene

1,3-DIFLUOROBENZEN

1,3-DIFLUOROBENZENE

1,3-DIFLUOROBENZENE, 99+%

1,3-DifluorobenzeneExtraPure

DIFLOUROBENZENE

1,3-Difluorbenzol

3-DifluoroBenzene

1,3-DIFLUOROBENZENEFLOCONAZOLE

1,3 DIFLOUROBENZENE extrapure

1,3-difluoro (between the two fluorophenyl)

Between difluorobenzene

1,3-Difluorobenzene, 99+% 10ML

1,3-Difluorobenzene &gt

1,3-Difluorobenzene ISO 9001：2015 REACH

1,3-Difluorobenzene (MDFB) extrapure, 99%

Voriconazole Impurity 39

1,3-Difluorobenzene 99% Extrapure

1,3-Di Fluoro Benzene (MDFB)

1,3-Difluorobenzene, 98%

1,3-Difluorobenzene 99% Colorless to light yellow liquid

1,3-DFB

372-18-9

C6H4F2CFCHCFCHCHCH

372189

Building Blocks

Aryl

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Halogenated Hydrocarbons

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Building Blocks

Chemical Synthesis

Fluorinated Building Blocks

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Organic Fluorinated Building Blocks

Other Fluorinated Organic Building Blocks

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Aromatic Hydrocarbons (substituted) & Derivatives

Fluorobenzene

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