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BENFLUOREX HYDROCHLORIDE

Product Name
BENFLUOREX HYDROCHLORIDE
CAS No.
23602-78-0
Chemical Name
BENFLUOREX HYDROCHLORIDE
Synonyms
s780;s992;S-780;jp992;se780;SE-780;D07192;Minolip;Mediaxal;BENFLUREX
CBNumber
CB0497956
Molecular Formula
C19H20F3NO2
Formula Weight
351.36
MOL File
23602-78-0.mol
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BENFLUOREX HYDROCHLORIDE Property

Boiling point:
420.5±45.0 °C(Predicted)
Density 
1.183±0.06 g/cm3(Predicted)
pka
8.23±0.10(Predicted)
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Safety

WGK Germany 
2
RTECS 
KL8275000
Toxicity
LD50 oral in mouse: 2300mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FB104002
Product name
Benfluorex
Packaging
500mg
Price
$40
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB104002
Product name
Benfluorex
Packaging
1g
Price
$65
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB104002
Product name
Benfluorex
Packaging
2g
Price
$100
Updated
2021/12/16
AK Scientific
Product number
0270CA
Product name
Benfluorex
Packaging
1g
Price
$137
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB104002
Product name
Benfluorex
Packaging
5G
Price
$200
Updated
2021/12/16
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BENFLUOREX HYDROCHLORIDE Chemical Properties,Usage,Production

Originator

Mediator,Servier,France,1976

Uses

antihyperlipoproteinemic

Definition

ChEBI: Benzoic acid 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl ester is a benzoate ester.

Manufacturing Process

To a solution of 24.7 parts of 1-(m-trifluoromethylphenyl)-2-(β- hydroxyethyl)amino propane in 140 parts of anhydrous benzene, there were added successively 15 parts of 4.7N hydrochloric ether and a solution of 14 parts of benzoyl chloride in 24 parts of anhydrous benzene. The addition required 10 minutes, the reaction mixture was then refluxed for 8 hours.
The solid product was collected by filtration and after recrystallization from 230 parts of ethyl acetate, there were obtained 15 parts of 1-(mtrifluoromethylphenyl)- 2-(β-benzoyloxyethyl)amino propane hydrochloride melting at 161°C.
10 parts hydrochloride are put in suspension in 100 parts of water, 80 parts ether are added, then 10 parts of a concentrated solution of ammonium hydroxide. The mixture is stirred a few minutes until the salt is dissolved, then the ethered solution is poured off and dried. After the ether is eliminated, 9 parts of 1-(m-trifluoromethylphenyl)-2-(β- benzoyloxyethyl)amino propane are obtained; the base is a colorless oil.

Therapeutic Function

Antihyperlipidemic, Cardiovascular

BENFLUOREX HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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BENFLUOREX HYDROCHLORIDE Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai Han-Xiang Chemical Co., Ltd.
Tel
15971444841
Fax
18327183813
Email
amber@biochempartner.com
Country
China
ProdList
3061
Advantage
58
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View Lastest Price from BENFLUOREX HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
BENFLUOREX HYDROCHLORIDE 23602-78-0
Price
US $2.00/KG
Min. Order
1KG
Purity
97%
Supply Ability
100g , 1kg, 5kg , 50kg
Release date
2020-01-07

23602-78-0, BENFLUOREX HYDROCHLORIDERelated Search:


  • benzoic acid 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl ester
  • Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, benzoate
  • jp992
  • Minolip
  • n-(2-hydroxyethyl)-alpha-methyl-m-trifluoromethyl-phenethylaminbenzoate
  • N-(2-Hydroxyethyl)-alpha-methyl-m-trifluoromethylphenethylamine benzoate
  • n-(2-hydroxyethyl)-alpha-methyl-m-trifluoromethylphenethylaminebenzoate
  • Phenethylamine, N-(2-hydroxyethyl)-alpha-methyl-m-trifluoromethyl-, benzoate
  • s780
  • S-780
  • s992
  • se780
  • SE-780
  • BENFLUREX
  • Benfluorex (base and/or unspecified salts)
  • Benzoic acid 2-[(α-methyl-3-trifluoromethylphenethyl)amino]ethyl ester
  • Benzoic acid 2-[[1-methyl-2-(3-trifluoromethylphenyl)ethyl]amino]ethyl ester
  • Benfluorex (inn/ban)
  • D07192
  • Mediaxal
  • Mediaxal (tn)
  • 1-(m-Trifluoromethylphenyl)-2-(benzoyloxy)ethylaminopropane
  • N-(2-Benzoyloxyethyl)norfenfluramine
  • Benzoyloxyfenfluramine
  • n-(1-methyl-2-(3-[trifluoromethyl]-phenyl)ethyl]aminoethanol benzoate ester
  • 2-((1-Methyl-2-[3-(trifluoromethyl)phenyl]ethyl)amino)ethyl benzoate
  • 2-(alpha-methyl-m-trifluoromethylphenethylamino)-ethanobenzoate
  • 2-(alpha-Methyl-m-trifluoromethylphenethylamino)ethanol benzoate
  • 2-(alpha-methyl-m-trifluoromethylphenethylamino)ethanolbenzoate
  • 2-[[alpha-Methyl-m-(trifluoromethyl)phenethyl]amino]ethanol benzoate (ester)
  • benfluramate
  • Ethanol, 2-(alpha-methyl-m-trifluoromethylphenethylamino)-, benzoate
  • Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, 1-benzoate
  • Benfluorex - API
  • BRN 4152887
  • 23602-78-0
  • C19H22F3NO3
  • C19H20F3NO2
  • MINOLIP