Uses
ChemicalBook > CAS DataBase List > CL 218872

CL 218872

Uses
Product Name
CL 218872
CAS No.
66548-69-4
Chemical Name
CL 218872
Synonyms
CI 218872;CL 218872;3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO;3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine;3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine;3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE;1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-;GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872
CBNumber
CB6312273
Molecular Formula
C13H9F3N4
Formula Weight
278.23
MOL File
66548-69-4.mol
More
Less

CL 218872 Property

Melting point:
193-194 °C(Solv: methanol (67-56-1))
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form 
A solid
pka
0.48±0.30(Predicted)
color 
Light yellow to brown
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Tocris
Product number
1709
Product name
CL218872
Purity
≥98%(HPLC)
Packaging
10
Price
$91
Updated
2021/12/16
Usbiological
Product number
255000
Product name
CL 218872
Packaging
10mg
Price
$339
Updated
2021/12/16
TRC
Product number
C560008
Product name
CL218872
Packaging
10mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0003622
Product name
3-METHYL-6-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE
Purity
95.00%
Packaging
1G
Price
$769.65
Updated
2021/12/16
ApexBio Technology
Product number
B6840
Product name
CL218872
Packaging
10mg
Price
$156
Updated
2021/12/16
More
Less

CL 218872 Chemical Properties,Usage,Production

Uses

CL 218872 is a useful research chemical. CL 218872 is a putative anxiolytic.

Uses

CL 218872 is a benzodiazepine receptor (BZR) partial agonist and a putative anxiolytic.

Definition

ChEBI: 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine is a member of pyridazines and a ring assembly.

Biological Activity

Benzodiazepine agonist displaying selectivity for α 1 subunit-containing GABA A receptors (K i values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α 1, α 2, α 3, α 4, α 5 and α 6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo .

storage

Store at RT

CL 218872 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

CL 218872 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
MQ (shanghai) Pharmaceuticals Co., Ltd.
Tel
13761635123
Fax
1014988033@qq
Email
1014988033@qq.com
Country
China
ProdList
4969
Advantage
55
Aikon International Limited
Tel
025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
Country
China
ProdList
15494
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17987
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-0371-55051623 18137891487
Fax
QQ:2853979817
Email
2853979817@qq.com
Country
China
ProdList
9868
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-63315541 13323832564
Fax
QQ:3001332135
Email
3001332135@qq.com
Country
China
ProdList
9892
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32063
Advantage
58
Changzhou Yinghao Technology Development Co., Ltd
Tel
15151934985
Email
sales@yingsapharm.com
Country
China
ProdList
4433
Advantage
58
More
Less

View Lastest Price from CL 218872 manufacturers

ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
Product
CL-218872
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg/month
Release date
2023-12-08
Henan Bao Enluo International TradeCo.,LTD
Product
CL 218872;3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine 66548-69-4
Price
US $100.00/kg
Min. Order
25kg
Purity
99%
Supply Ability
500t/month
Release date
2023-05-24

66548-69-4, CL 218872Related Search:


  • 3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO
  • 1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-
  • 3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine
  • CL 218872
  • 3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE
  • CI 218872
  • 3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine
  • GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872
  • 66548-69-4