CL 218872

Uses

Product Name: CL 218872
CAS No.: 66548-69-4
Chemical Name: CL 218872
Synonyms: CI 218872;CL 218872;3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO;3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine;3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine;3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE;1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-;GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872
CBNumber: CB6312273
Molecular Formula: C13H9F3N4
Formula Weight: 278.23
MOL File: 66548-69-4.mol

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CL 218872 Property

Melting point:: 193-194 °C(Solv: methanol (67-56-1))
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form: A solid
pka: 0.48±0.30(Predicted)
color: Light yellow to brown

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris

Product number: 1709
Product name: CL218872
Purity: ≥98%(HPLC)
Packaging: 10
Price: $91
Updated: 2021/12/16

TRC

Product number: C560008
Product name: CL218872
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Usbiological

Product number: 255000
Product name: CL 218872
Packaging: 10mg
Price: $339
Updated: 2021/12/16

ApexBio Technology

Product number: B6840
Product name: CL218872
Packaging: 10mg
Price: $156
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0003622
Product name: 3-METHYL-6-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE
Purity: 95.00%
Packaging: 1G
Price: $769.65
Updated: 2021/12/16

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CL 218872 Chemical Properties,Usage,Production

Uses

CL 218872 is a useful research chemical.CL 218872 is a putative anxiolytic.

Uses

CL 218872 is a benzodiazepine receptor (BZR) partial agonist and a putative anxiolytic.

Definition

ChEBI: 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine is a member of pyridazines and a ring assembly.

Biological Activity

Benzodiazepine agonist displaying selectivity for α 1 subunit-containing GABA A receptors (K i values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α 1, α 2, α 3, α 4, α 5 and α 6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo .

storage

Store at RT

CL 218872 Preparation Products And Raw materials

Raw materials

Preparation Products

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CL 218872 Suppliers

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View Lastest Price from CL 218872 manufacturers

ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD

Product: CL-218872
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg/month
Release date: 2023-12-08

Henan Bao Enluo International TradeCo.，LTD

Product: CL 218872;3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine 66548-69-4
Price: US $100.00/kg
Min. Order: 25kg
Purity: 99%
Supply Ability: 500t/month
Release date: 2023-05-24

66548-69-4, CL 218872Related Search:

4-AMINO-3,5-DIMETHYL-1,2,4-TRIAZOLE CL 218872

3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO

1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-

3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine

CL 218872

3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE

CI 218872

3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine

GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872

66548-69-4