ChemicalBook > CAS DataBase List > CL 218872

CL 218872

Uses

Product Name: CL 218872
CAS No.: 66548-69-4
Chemical Name: CL 218872
Synonyms: CI 218872;CL 218872;CL 218872, 10 mM in DMSO;3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO;3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine;3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine;3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE;1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-;GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872
CBNumber: CB6312273
Molecular Formula: C13H9F3N4
Formula Weight: 278.23
MOL File: 66548-69-4.mol

Less

CL 218872 Property

Melting point:: 193-194 °C(Solv: methanol (67-56-1))
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form: A solid
pka: 0.48±0.30(Predicted)
color: Light yellow to brown

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

Tocris

Product number: 1709
Product name: CL218872
Purity: ≥98%(HPLC)
Packaging: 10
Price: $91
Updated: 2021/12/16

TRC

Product number: C560008
Product name: CL218872
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Usbiological

Product number: 255000
Product name: CL 218872
Packaging: 10mg
Price: $339
Updated: 2021/12/16

ApexBio Technology

Product number: B6840
Product name: CL218872
Packaging: 10mg
Price: $156
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0003622
Product name: 3-METHYL-6-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE
Purity: 95.00%
Packaging: 1G
Price: $769.65
Updated: 2021/12/16

Less

CL 218872 Chemical Properties,Usage,Production

Uses

CL 218872 is a useful research chemical.CL 218872 is a putative anxiolytic.

Uses

CL 218872 is a benzodiazepine receptor (BZR) partial agonist and a putative anxiolytic.

Definition

ChEBI: 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine is a member of pyridazines and a ring assembly.

Biological Activity

Benzodiazepine agonist displaying selectivity for α 1 subunit-containing GABA A receptors (K i values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α 1, α 2, α 3, α 4, α 5 and α 6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo .

storage

Store at RT

CL 218872 Preparation Products And Raw materials

Raw materials

Preparation Products

Less

CL 218872 Suppliers

Canada 1 China 49 Germany 1 India 1 Switzerland 1 United Kingdom 4 United States 12 Global 69

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Shanghai Arbor Chemical Co., Ltd.

Tel: 021-60451683 15021268886
Fax: +86-21-60451682
Email: sales@arborchemical.com
Country: China
ProdList: 896
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

MQ (shanghai) Pharmaceuticals Co., Ltd.

Tel: 13761635123
Fax: 1014988033@qq
Email: 1014988033@qq.com
Country: China
ProdList: 4941
Advantage: 55

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Henan Alfachem Co.,Ltd.

Tel: 0371-55051623 18137891487
Fax: QQ：2853979817
Email: 2853979817@qq.com
Country: China
ProdList: 9985
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-63315541 13323832564
Fax: QQ:3001332135
Email: 3001332135@qq.com
Country: China
ProdList: 9972
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-029-81024372 17792795018
Fax: 029-88380327
Email: 1027@dideu.com
Country: China
ProdList: 9997
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 13675144456
Fax: 025-85563444
Email: sean.lv@synzest.com
Country: China
ProdList: 11438
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

CHANGZHOU GARDE PHARMTECH CO.,LTD

Tel: 18006124028
Email: gardepharm@163.com
Country: China
ProdList: 117
Advantage: 58

cjbscvictory

Tel: 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10503
Advantage: 58

Jinan Jiuli Biotechnology Co. , Ltd.

Tel: 15865264761
Email: 486064515@qq.com
Country: China
ProdList: 4809
Advantage: 58

JinOu Biomedical (Nanjing) Co., Ltd.

Tel: 13000000000
Fax: jinoupharma@163
Email: jinoupharma@163.com
Country: China
ProdList: 11721
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 15921930842 15921930842
Email: yh-wang@univ-bio.com
Country: China
ProdList: 25004
Advantage: 58

Suzhou Daolan Biomedical Technology Co., Ltd.

Tel: 15952404857
Email: sales@dolanpharm.com
Country: China
ProdList: 2920
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Suzhou Zhixin Biotechnology Co., Ltd.

Tel: 0512-65118909 18100677375
Email: sales@szzxbio.com
Country: China
ProdList: 2993
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 39845
Advantage: 58

Wuhan Fengyao Tonghui Chemical Products Co. LTD

Tel: 027-87466205 15377579727
Email: 1228964013@qq.com
Country: China
ProdList: 8558
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Shanghai Arbor Chemical Co., Ltd.

Tel: 021-60451683 15001705751
Email: market@arborpharmchem.com
Country: China
ProdList: 1996
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Shaanxi Didu New Materials Co. Ltd

Tel: +86-89586680 +86-13289823923
Email: 1026@dideu.com
Country: China
ProdList: 9080
Advantage: 58

Henan Bao Enluo International TradeCo.，LTD

Tel: +86-17331933971
Fax: deasea125996@gmail.com
Email: deasea125996@gmail.com
Country: China
ProdList: 2472
Advantage: 58

Golden Pharma Co., Limited

Tel: +undefined18958062155
Email: sales@zjgoldpharm.com
Country: China
ProdList: 5899
Advantage: 58

Nanjing Doge Biomedical Technology Co., Ltd

Tel: +86-25-58227606 +86-15305155328
Email: sales@dogechemical.com
Country: China
ProdList: 4128
Advantage: 58

Guangzhou Chengguo Biological Co., Ltd.

Tel: 14743339820
Country: CHINA
ProdList: 181
Advantage: 58

Guangzhou Huiran Biochemical Technology Co., Ltd.

Tel: 15817162434
Country: CHINA
ProdList: 134
Advantage: 58

Guangzhou Taozhu Biotechnology Co., Ltd

Tel: 4008200310
Country: CHINA
ProdList: 111
Advantage: 58

Neobioscience Co., Ltd.

Tel: --
Fax: --
Email: info@neobioscience.com
Country: CHINA
ProdList: 6207
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

Beijing Taize Jiaye Technology Development Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6050
Advantage: 58

Shanghai Yihui Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: yihbio@163.com
Country: CHINA
ProdList: 6184
Advantage: 58

Shanghai Chaoyan Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 471161314@qq.com
Country: CHINA
ProdList: 6210
Advantage: 58

Beijing Bolide Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1985563437@qq.com
Country: CHINA
ProdList: 6525
Advantage: 58

Shanghai Gantu Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 1920192055@qq.com
Country: CHINA
ProdList: 1843
Advantage: 58

Shanghai Yuda Industrial Co., Ltd.

Tel: --
Fax: --
Email: lucy@runwelltac.com
Country: CHINA
ProdList: 6448
Advantage: 58

Shanghai Weiwei Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: sales@wheybio.com
Country: CHINA
ProdList: 4398
Advantage: 58

Shanghai Haoyang Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 596799915@QQ.COM
Country: CHINA
ProdList: 2905
Advantage: 58

Guangzhou WeiBo Chemical Co., Ltd.

Tel: --
Fax: --
Email: weibochem@163.com
Country: China
ProdList: 6187
Advantage: 67

Shanghai PI Chemicals Ltd.

Tel: --
Fax: --
Email: sales@pipharm.com
Country: China
ProdList: 6344
Advantage: 56

Less

View Lastest Price from CL 218872 manufacturers

Shaanxi Didu New Materials Co. Ltd

Product: CL 218872 66548-69-4
Price: US $1.50/g
Min. Order: 1g
Purity: 99.0% Min
Supply Ability: 10 Tons
Release date: 2025-06-24

ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD

Product: CL-218872
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg/month
Release date: 2023-12-08

Henan Bao Enluo International TradeCo.，LTD

Product: CL 218872;3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine 66548-69-4
Price: US $100.00/kg
Min. Order: 25kg
Purity: 99%
Supply Ability: 500t/month
Release date: 2023-05-24

66548-69-4, CL 218872Related Search:

4-AMINO-3,5-DIMETHYL-1,2,4-TRIAZOLE CL 218872

3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO

1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-

3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine

CL 218872

3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE

CI 218872

3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine

GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872

CL 218872, 10 mM in DMSO

66548-69-4