Uses
ChemicalBook > CAS DataBase List > CL 218872

CL 218872

Uses
Product Name
CL 218872
CAS No.
66548-69-4
Chemical Name
CL 218872
Synonyms
CI 218872;CL 218872;3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO;3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine;3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine;3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE;1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-;GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872
CBNumber
CB6312273
Molecular Formula
C13H9F3N4
Formula Weight
278.23
MOL File
66548-69-4.mol
More
Less

CL 218872 Property

Melting point:
193-194 °C(Solv: methanol (67-56-1))
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form 
A solid
pka
0.48±0.30(Predicted)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Tocris
Product number
1709
Product name
CL218872
Purity
≥98%(HPLC)
Packaging
10
Price
$91
Updated
2021/12/16
Usbiological
Product number
255000
Product name
CL 218872
Packaging
10mg
Price
$339
Updated
2021/12/16
TRC
Product number
C560008
Product name
CL218872
Packaging
10mg
Price
$45
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0003622
Product name
3-METHYL-6-[3-(TRIFLUOROMETHYL)PHENYL]-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE
Purity
95.00%
Packaging
1G
Price
$769.65
Updated
2021/12/16
ApexBio Technology
Product number
B6840
Product name
CL218872
Packaging
10mg
Price
$156
Updated
2021/12/16
More
Less

CL 218872 Chemical Properties,Usage,Production

Uses

CL 218872 is a useful research chemical. CL 218872 is a putative anxiolytic.

Uses

CL 218872 is a benzodiazepine receptor (BZR) partial agonist and a putative anxiolytic.

Definition

ChEBI: 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[4,3-b]pyridazine is a member of pyridazines and a ring assembly.

Biological Activity

Benzodiazepine agonist displaying selectivity for α 1 subunit-containing GABA A receptors (K i values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α 1, α 2, α 3, α 4, α 5 and α 6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo .

storage

Store at RT

CL 218872 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

View Lastest Price from CL 218872 manufacturers

ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
Product
CL-218872
Price
US $1.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kg/month
Release date
2023-12-08
Henan Bao Enluo International TradeCo.,LTD
Product
CL 218872;3-Methyl-6-[-3-(trifluoroMethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine 66548-69-4
Price
US $100.00/kg
Min. Order
25kg
Purity
99%
Supply Ability
500t/month
Release date
2023-05-24

66548-69-4, CL 218872Related Search:


  • 3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO
  • 1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-
  • 3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine
  • CL 218872
  • 3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE
  • CI 218872
  • 3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine
  • GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872
  • 66548-69-4