(1S,2S,3S)-Aprepitant

Product Name: (1S,2S,3S)-Aprepitant
CAS No.: 1242175-40-1
Chemical Name: (1S,2S,3S)-Aprepitant
Synonyms: Aprepitant Impurity 5;Aprepitant iMpurity 30;Aprepitant (S,S,S)-Isomer;Aprepitant Impurity 7(S,S,S-Isomer);Arepitam impurity isomers (1S, 2S, 3S);Aprepitant impurity 10/(S,S,S)-Aprepitant;3H-1,2,4-Triazol-3-one, 5-[[(2S,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
CBNumber: CB63146510
Molecular Formula: C23H21F7N4O3
Formula Weight: 534.43
MOL File: 1242175-40-1.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A729780
Product name: (S,S,S)-Aprepitant
Packaging: 10mg
Price: $1050
Updated: 2021/12/16

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(1S,2S,3S)-Aprepitant Chemical Properties,Usage,Production

Uses

(S,S,S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(1S,2S,3S)-Aprepitant Preparation Products And Raw materials

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1242175-40-1, (1S,2S,3S)-AprepitantRelated Search:

[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (R,R,R)-Aprepitant Aprepitant 1,1,1-Trimethoxy-2-chloroethane Aprepitant Impurity A Enantiomer Aprepitant (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine Aprepitant Impurity 19 (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol Fosaprepitant Impurity 6 (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one Aprepitant Impurity 17 Aprepitant Defluoro Aprepitant Aprepitant Impurity B HCl 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 11 HCl Aprepitant Impurity 2

Aprepitant Impurity 5

Aprepitant impurity 10/(S,S,S)-Aprepitant

Arepitam impurity isomers (1S, 2S, 3S)

Aprepitant (S,S,S)-Isomer

Aprepitant Impurity 7(S,S,S-Isomer)

Aprepitant iMpurity 30

3H-1,2,4-Triazol-3-one, 5-[[(2S,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-

1242175-40-1