5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE
- Product Name
- 5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE
- CAS No.
- 485841-48-3
- Chemical Name
- 5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE
- Synonyms
- 5-Fluoroindazole-3-carbaldehyde;5-FLUORO INDAZOLE-3-CARBOXALDEHYDE;5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE;5-fluoro-2H-indazole-3-carboxaldehyde;5-fluoro-1H-Indazole-3-carboxaldehyde;5-Fluoro-3-(1H)indazolecarboxyaldehyde;5-FLUORO-3-(1H)INDAZOLE CARBOXALDEHYDE;1H-Indazole-3-carboxaldehyde, 5-fluoro-;1H-Indazole-3-carboxaldehyde,5-fluoro-(9CI)
- CBNumber
- CB6315047
- Molecular Formula
- C8H5FN2O
- Formula Weight
- 164.14
- MOL File
- 485841-48-3.mol
5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- Appearance
- White to light brown Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PC903633
- Product name
- 5-Fluoro-1H-indazole-3-carbaldehyde
- Purity
- 98%
- Packaging
- 50mg
- Price
- $36
- Updated
- 2021/12/16
- Product number
- PC903633
- Product name
- 5-Fluoro-1H-indazole-3-carbaldehyde
- Purity
- 98%
- Packaging
- 100mg
- Price
- $58
- Updated
- 2021/12/16
- Product number
- 4H15-3-20
- Product name
- 5-Fluoro-1H-indazole-3-carbaldehyde
- Purity
- 96%
- Packaging
- 50mg
- Price
- $58
- Updated
- 2021/12/16
- Product number
- 4H15-3-20
- Product name
- 5-Fluoro-1H-indazole-3-carbaldehyde
- Purity
- 96%
- Packaging
- 100mg
- Price
- $93
- Updated
- 2021/12/16
- Product number
- CS-0060650
- Product name
- 5-Fluoro-1H-indazole-3-carbaldehyde
- Purity
- ≥97.0%
- Packaging
- 100mg
- Price
- $101
- Updated
- 2021/12/16
5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE Chemical Properties,Usage,Production
Uses
5-fluoro-1H-indazole-3-carbaldehyde is used as a key intermediate in the synthesis of a variety of polyfunctionalized 3-substituted indazoles.
Synthesis
518990-02-8
485841-48-3
Step 3: Manganese dioxide (1.12 g, 12.9 mmol) was added to a solution of (5-fluoro-1H-indazol-3-yl)methanol (0.215 g, 1.29 mmol) in ethyl acetate (10 mL) at room temperature. The reaction mixture was stirred overnight and filtered through diatomaceous earth. The filtrate was concentrated and the resulting residue was purified by silica gel column chromatography (eluent: chloroform/methanol) to afford 5-fluoro-1H-indazole-3-carbaldehyde (0.150 g, 70% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 7.41 (ddd, J = 2.2,8.8,9.5 Hz, 1H), 7.75-7.81 (m, 2H), 10.18 (s, 1H), 14.32 (br s, 1H).
References
[1] Patent: EP2565192, 2013, A1. Location in patent: Paragraph 0352
5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE Suppliers
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 027-86697669 13986148687
- Fax
- 86-027-86697669
- sales@tcaschem.com
- Country
- China
- ProdList
- 3993
- Advantage
- 55
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
- Tel
- 021-57171705 13817537615
- Fax
- QQ3095748324
- sales@run-biotech.com
- Country
- China
- ProdList
- 2339
- Advantage
- 58
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 0755-0755-89366401 18617066401
- Fax
- -
- hangbingfang@163.com
- Country
- China
- ProdList
- 951
- Advantage
- 55
- Tel
- 021-64340559 13651849907;
- Fax
- 021- 64345308
- xinyu_shi@jwypharmlab.com.cn
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- 021-34979681; 17701870669
- Fax
- 021-34979681
- 41513101@qq.com
- Country
- China
- ProdList
- 1785
- Advantage
- 55
- Tel
- 021-58088081 Q2635253576
- Fax
- QQ3382968513
- hailey@shsendpharm.com
- Country
- China
- ProdList
- 2081
- Advantage
- 55
- Tel
- 0512-0512-52358471 17715136450
- Fax
- 05125235 6881
- sales@shiyabiopharm.com
- Country
- China
- ProdList
- 12127
- Advantage
- 58
View Lastest Price from 5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE manufacturers
- Product
- 5-FLUORO-1H-INDAZOLE-3-CARBALDEHYDE 485841-48-3
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-12