5-FLUORO-1H-INDAZOLE

Product Name: 5-FLUORO-1H-INDAZOLE
CAS No.: 348-26-5
Chemical Name: 5-FLUORO-1H-INDAZOLE
Synonyms: 5-Fluoroindazole;5-FLUORO-1H-INDAZOLE;1H-Indazole, 5-fluoro-;5-Fluoro-1H-indazole;5-fluoro-1H-indazole(SALTDATA: FREE)
CBNumber: CB6179166
Molecular Formula: C7H5FN2
Formula Weight: 136.13
MOL File: 348-26-5.mol

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5-FLUORO-1H-INDAZOLE Property

Melting point:: 119-125 °C
Boiling point:: 274.9±13.0 °C(Predicted)
Density: 1.370±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 12.90±0.40(Predicted)
form: solid
color: Beige
CAS DataBase Reference: 348-26-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 701025
Product name: 5-Fluoro-1H-indazole
Purity: 97%
Packaging: 500mg
Price: $118
Updated: 2023/01/07

TRC

Product number: F595478
Product name: 5-Fluoro-1H-indazole
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: F595478
Product name: 5-Fluoro-1H-indazole
Packaging: 500mg
Price: $65
Updated: 2021/12/16

TRC

Product number: F595478
Product name: 5-Fluoro-1H-indazole
Packaging: 1g
Price: $75
Updated: 2021/12/16

Apolloscientific

Product number: PC5711
Product name: 5-Fluoro-1H-indazole
Packaging: 250mg
Price: $10
Updated: 2021/12/16

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5-FLUORO-1H-INDAZOLE Chemical Properties,Usage,Production

Uses

5-Fluoro-1H-indazole(Indazole compound) or its physiologically acceptable derivative are respectively provided with the effect for inhibiting Rho kinase activity；It is thin with promoting The effect of born of the same parents' glucose consumption.

Synthesis

141071-11-6

348-26-5

Step 2: Preparation of 5-fluoro-1H-indazole 1-(5-Fluoro-1H-indazol-1-yl)ethan-1-one (2.1 g, 11.8 mmol) was dissolved in a mixture of methanol (20 mL) and concentrated hydrochloric acid (10 mL), heated to 50 °C and maintained for 2 hours. Upon completion of the reaction, the reaction mixture was evaporated to dryness under reduced pressure. The residue was alkalized with saturated sodium bicarbonate solution and extracted with ethyl acetate, the organic phase was washed with water and concentrated to afford the target product 5-fluoro-1H-indazole (1.6 g, 100% yield). The purity was analyzed by LCMS and was 95.9%; m/z = 137.2.

References

[1] Patent: WO2015/193846, A1. Location in patent: Page/Page column 80
[1] Patent: , 2015, . Location in patent: Page/Page column 80

5-FLUORO-1H-INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-FLUORO-1H-INDAZOLE Suppliers

China 135 France 1 Germany 4 India 3 Switzerland 1 United Kingdom 8 United States 27 Global 179

Shanghai Boyle Chemical Co., Ltd.

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View Lastest Price from 5-FLUORO-1H-INDAZOLE manufacturers

Career Henan Chemical Co

Product: 5-FLUORO-1H-INDAZOLE 348-26-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

348-26-5, 5-FLUORO-1H-INDAZOLERelated Search:

5-fluoro-1H-indazol-3-amine METHYL 5-FLUORO-1H-INDAZOLE-3-CARBOXYLATE 5-FLUORO-1H-INDAZOLE 5-Fluoro-3-iodo-1H-indazole 5-FLUORO-1-METHYL-1H-INDAZOLE-3-CARBOXYLIC ACID 5-FLUORO-1H-INDAZOLE-3-CARBOXYLIC ACID 4-BROMO-6-FLUORO (1H)INDAZOLE 4-FLUORO (1H)INDAZOLE 7-FLUORO INDAZOLE 1H-Indazol-5-amine,6-fluoro-(9CI) 3-Amino-4-fluoro-1-methylindazole 6-FLUORO (1H)INDAZOLE Indazole 1-BOC-3-BROMO-5-FLUORO-INDAZOLE (5-FLUORO-1H-INDAZOL-3-YL)-METHANOL 5,6-DIFLUORO-1H-INDAZOLE-3-CARBONITRILE (5-FLUORO-1H-INDAZOL-3-YL)-ACETIC ACID ETHYL ESTER ETHYL 5,6-DIFLUORO-1H-INDAZOLE-3-CARBOXYLATE

5-FLUORO-1H-INDAZOLE

1H-Indazole, 5-fluoro-

5-fluoro-1H-indazole(SALTDATA: FREE)

5-Fluoroindazole

5-Fluoro-1<i>H</i>-indazole

348-26-5

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