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ChemicalBook > CAS DataBase List > 7-FLUORO INDAZOLE

7-FLUORO INDAZOLE

Uses
Product Name
7-FLUORO INDAZOLE
CAS No.
341-24-2
Chemical Name
7-FLUORO INDAZOLE
Synonyms
7-FLUORO INDAZOLE;7-Fluoro-1H-indazole;1H-Indazole, 7-fluoro-;7-fluoro-1(2)H-indazole
CBNumber
CB9820894
Molecular Formula
C7H5FN2
Formula Weight
136.13
MOL File
341-24-2.mol
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7-FLUORO INDAZOLE Property

Melting point:
120 °C (decomp)
Boiling point:
274.9±13.0 °C(Predicted)
Density 
1.370±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
12.10±0.40(Predicted)
Appearance
Light yellow to yellow Solid
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F595488
Product name
7-Fluoro-1H-indazole
Packaging
250mg
Price
$55
Updated
2021/12/16
Apolloscientific
Product number
PC201233
Product name
7-Fluoro-1H-indazole
Purity
98%
Packaging
10g
Price
$57
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-3-49
Product name
7-Fluoro-1H-indazole
Purity
97%
Packaging
5G
Price
$68
Updated
2021/12/16
AK Scientific
Product number
W5563
Product name
7-Fluoro-1H-indazole
Packaging
1g
Price
$84
Updated
2021/12/16
Apolloscientific
Product number
PC201233
Product name
7-Fluoro-1H-indazole
Purity
98%
Packaging
1g
Price
$10
Updated
2021/12/16
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7-FLUORO INDAZOLE Chemical Properties,Usage,Production

Uses

7-Fluoro-1H-indazole is a heterocyclic organic compound that can be used as a pharmaceutical intermediate.

Synthesis

2646-91-5

341-24-2

General procedure for the synthesis of 7-fluoro-1H-indazole from 2,3-difluorobenzaldehyde: To 2,3-difluorobenzaldehyde (1.85 g) was added hydrazine monohydrate (3 ml), and the reaction mixture was heated with stirring at 180°C for 10 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted by adding ethyl acetate and water to separate the organic layer. The organic layer was washed with saturated brine, dried over anhydrous sodium sulfate and subsequently evaporated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography to afford 7-fluoro-1H-indazole (790 mg, 45% yield) using chloroform/acetone as eluent. The structure of the product was confirmed by 1H-NMR (CD3OD, 400 MHz): δ 7.08-7.12 (m, 2H), 7.56-7.59 (m, 1H), 8.10 (d, J = 3.4 Hz, 1H).

References

[1] Patent: EP1870414, 2007, A1. Location in patent: Page/Page column 23
[2] Patent: EP2752410, 2014, A1. Location in patent: Paragraph 0626

7-FLUORO INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-FLUORO INDAZOLE Suppliers

Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
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United States
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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chenyj@titansci.com
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China
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14101
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ZEROSCHEM.CO.,LTD.
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10-61256048 13810278579
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+86 10 61256049
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sales@zeroschem.com
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China
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China DongFan Chemical Co.,LTD
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86-0571-85151182
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86-0571-85151182
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China
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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0539-6365991
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3007715519@qq.com
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China
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18729
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Shanghai Ennopharm Co., Ltd.
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+86 (21) 6435-5022
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China
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Cantotech Chemicals, Ltd.
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86-0755-86635001
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86-0755-22642228
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cantotech@126.com
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China
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Shanghai Yolne Chemical Co., Ltd.
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021-62960152
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021-52212593
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934678158@qq.com
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China
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Shanghai Raise Chemical Technology Co.,Ltd
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+86-021-50935922
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+86-021-33847795
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China
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Bide Pharmatech Ltd.
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400-164-7117 13681763483
Fax
+86-21-61629029
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product02@bidepharm.com
Country
China
ProdList
39966
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View Lastest Price from 7-FLUORO INDAZOLE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
7-FLUORO INDAZOLE 341-24-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
7-FLUORO INDAZOLE 341-24-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
7-FLUORO INDAZOLE 341-24-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-01