ChemicalBook > CAS DataBase List > 5-FLUORO-1H-INDAZOLE

5-FLUORO-1H-INDAZOLE

Product Name
5-FLUORO-1H-INDAZOLE
CAS No.
348-26-5
Chemical Name
5-FLUORO-1H-INDAZOLE
Synonyms
5-Fluoroindazole;5-FLUORO-1H-INDAZOLE;1H-Indazole, 5-fluoro-;5-Fluoro-1H-indazole;5-fluoro-1H-indazole(SALTDATA: FREE)
CBNumber
CB6179166
Molecular Formula
C7H5FN2
Formula Weight
136.13
MOL File
348-26-5.mol
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5-FLUORO-1H-INDAZOLE Property

Melting point:
119-125 °C
Boiling point:
274.9±13.0 °C(Predicted)
Density 
1.370±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
12.90±0.40(Predicted)
form 
solid
color 
Beige
CAS DataBase Reference
348-26-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
701025
Product name
5-Fluoro-1H-indazole
Purity
97%
Packaging
500mg
Price
$118
Updated
2023/01/07
TRC
Product number
F595478
Product name
5-Fluoro-1H-indazole
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
F595478
Product name
5-Fluoro-1H-indazole
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
F595478
Product name
5-Fluoro-1H-indazole
Packaging
1g
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
PC5711
Product name
5-Fluoro-1H-indazole
Packaging
250mg
Price
$10
Updated
2021/12/16
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5-FLUORO-1H-INDAZOLE Chemical Properties,Usage,Production

Uses

5-Fluoro-1H-indazole(Indazole compound) or its physiologically acceptable derivative are respectively provided with the effect for inhibiting Rho kinase activity；It is thin with promoting The effect of born of the same parents' glucose consumption.

Synthesis

141071-11-6

348-26-5

Step 2: Preparation of 5-fluoro-1H-indazole 1-(5-Fluoro-1H-indazol-1-yl)ethan-1-one (2.1 g, 11.8 mmol) was dissolved in a mixture of methanol (20 mL) and concentrated hydrochloric acid (10 mL), heated to 50 °C and maintained for 2 hours. Upon completion of the reaction, the reaction mixture was evaporated to dryness under reduced pressure. The residue was alkalized with saturated sodium bicarbonate solution and extracted with ethyl acetate, the organic phase was washed with water and concentrated to afford the target product 5-fluoro-1H-indazole (1.6 g, 100% yield). The purity was analyzed by LCMS and was 95.9%; m/z = 137.2.

References

[1] Patent: WO2015/193846, A1. Location in patent: Page/Page column 80
[1] Patent: , 2015, . Location in patent: Page/Page column 80

5-FLUORO-1H-INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-FLUORO-1H-INDAZOLE Suppliers

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View Lastest Price from 5-FLUORO-1H-INDAZOLE manufacturers

Career Henan Chemical Co
Product
5-FLUORO-1H-INDAZOLE 348-26-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-01

348-26-5, 5-FLUORO-1H-INDAZOLERelated Search:

5-fluoro-1H-indazol-3-amine METHYL 5-FLUORO-1H-INDAZOLE-3-CARBOXYLATE 5-FLUORO-1H-INDAZOLE 5-Fluoro-3-iodo-1H-indazole 5-FLUORO-1-METHYL-1H-INDAZOLE-3-CARBOXYLIC ACID 5-FLUORO-1H-INDAZOLE-3-CARBOXYLIC ACID 4-BROMO-6-FLUORO (1H)INDAZOLE 4-FLUORO (1H)INDAZOLE 7-FLUORO INDAZOLE 1H-Indazol-5-amine,6-fluoro-(9CI) 3-Amino-4-fluoro-1-methylindazole 6-FLUORO (1H)INDAZOLE Indazole 1-BOC-3-BROMO-5-FLUORO-INDAZOLE (5-FLUORO-1H-INDAZOL-3-YL)-METHANOL 5,6-DIFLUORO-1H-INDAZOLE-3-CARBONITRILE (5-FLUORO-1H-INDAZOL-3-YL)-ACETIC ACID ETHYL ESTER ETHYL 5,6-DIFLUORO-1H-INDAZOLE-3-CARBOXYLATE

  • 5-FLUORO-1H-INDAZOLE
  • 1H-Indazole, 5-fluoro-
  • 5-fluoro-1H-indazole(SALTDATA: FREE)
  • 5-Fluoroindazole
  • 5-Fluoro-1<i>H</i>-indazole
  • 348-26-5
  • Building Blocks
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  • Fluorinated Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
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  • Indoles and derivatives
  • Halogenated Heterocycles
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  • Indazoles