1H-INDAZOLE-3-CARBALDEHYDE

Product Name: 1H-INDAZOLE-3-CARBALDEHYDE
CAS No.: 5235-10-9
Chemical Name: 1H-INDAZOLE-3-CARBALDEHYDE
Synonyms: 3-Formylindazole;3-Formyl-1H-indazole;3-Indazolecarbadehyde;3-INDAZOLECARBALDEHYDE;1H-indazole-3-aldehyde;indazole-3-carbaldehyde;Indazole-3-carboxaldehyde;INDAZOLE-3-CARBOXYALDEHYDE;1H-INDAZOLE-3-CARBALDEHYDE;1H-INDAZOLE-3-CARBOXALDEHYDE
CBNumber: CB8309369
Molecular Formula: C8H6N2O
Formula Weight: 146.15
MOL File: 5235-10-9.mol

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1H-INDAZOLE-3-CARBALDEHYDE Property

Melting point:: 131-132 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
Boiling point:: 358.3±15.0 °C(Predicted)
Density: 1.368±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: crystalline powder
pka: 12.04±0.40(Predicted)
color: Light yellow
CAS DataBase Reference: 5235-10-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Frontier Specialty Chemicals

Product number: F12293
Product name: 3-Formylindazole
Purity: 95%
Packaging: 1g
Price: $15
Updated: 2021/12/16

AK Scientific

Product number: J99710
Product name: 1H-Indazole-3-carbaldehyde
Packaging: 1g
Price: $23
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: F12293
Product name: 3-Formylindazole
Purity: 95%
Packaging: 5g
Price: $50
Updated: 2021/12/16

Matrix Scientific

Product number: 144810
Product name: 1H-Indazole-3-carbaldehyde
Purity: 95%
Packaging: 1g
Price: $89
Updated: 2021/12/16

Matrix Scientific

Product number: 144810
Product name: 1H-Indazole-3-carbaldehyde
Purity: 95%
Packaging: 5g
Price: $330
Updated: 2021/12/16

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1H-INDAZOLE-3-CARBALDEHYDE Chemical Properties,Usage,Production

Antimicrobial activity

1H-Indazole-3-carbaldehyde has been shown to have antibacterial activity by inhibiting bacterial cell wall synthesis and fluorescence probe activity. It also interacts with 3-hydroxybenzoic acid, which may lead to fluorescent microscopy and efficient methods.

Synthesis

64132-13-4

5235-10-9

The general procedure for the synthesis of 3-formylindazole from 3-hydroxymethylindazole is as follows: 1. (1H-indazol-3-yl)-methanol (200 mg, 1.35 mmol) was dissolved in dichloromethane (10 mL). 2. manganese dioxide (MnO?, 1.3 g, 13.46 mmol) was added to the above solution. 3. The reaction mixture was stirred at room temperature for 16 hours. 4. 4. Upon completion of the reaction, the mixture was filtered to remove the solid catalyst. 5. The filtrate was concentrated to give 1H-indazole-3-carbaldehyde (150 mg, 76% yield). Product characterization data: - Mass spectrum (MS): m/z = 145.0 (API-). - 1H-NMR (400 MHz, DMSO-d6): δ (ppm) = 7.37 (t, 1H), 7.51 (t, 1H), 7.71 (d, 1H), 8.14 (d, 1H), 10.20 (s, 1H, aldehydic hydrogen), 14.17 (br, 1H, indazole NH).

References

[1] Patent: US2006/142247, 2006, A1. Location in patent: Page/Page column 28
[2] Patent: WO2005/9958, 2005, A1. Location in patent: Page 100-101
[3] Patent: US2005/9894, 2005, A1. Location in patent: Page 18; 27

1H-INDAZOLE-3-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-INDAZOLE-3-CARBALDEHYDE Suppliers

China 110 Germany 1 India 2 United Kingdom 4 United States 23 Global 140

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View Lastest Price from 1H-INDAZOLE-3-CARBALDEHYDE manufacturers

PNP Biotech Co. Ltd

Product: 1H-indazole-3-carboxaldehyde 5235-10-9
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-06-26

5235-10-9, 1H-INDAZOLE-3-CARBALDEHYDERelated Search:

1H-INDAZOLE-3-CARBALDEHYDE

1H-INDAZOLE-3-CARBOXALDEHYDE

1H-INDAZOLE-3-CARBOXYALDEHYDE

3-INDAZOLECARBALDEHYDE

INDAZOLE-3-CARBOXYALDEHYDE

Indazole-3-carboxaldehyde

3-Formylindazole

3-Formyl-1H-indazole

indazole-3-carbaldehyde

1H-indazole-3-aldehyde

3-Indazolecarbadehyde

5235-10-9

1218-36-7

pharmacetical