1H-INDAZOLE-3-CARBALDEHYDE
- Product Name
- 1H-INDAZOLE-3-CARBALDEHYDE
- CAS No.
- 5235-10-9
- Chemical Name
- 1H-INDAZOLE-3-CARBALDEHYDE
- Synonyms
- 3-Formylindazole;3-Formyl-1H-indazole;3-Indazolecarbadehyde;3-INDAZOLECARBALDEHYDE;1H-indazole-3-aldehyde;indazole-3-carbaldehyde;Indazole-3-carboxaldehyde;INDAZOLE-3-CARBOXYALDEHYDE;1H-INDAZOLE-3-CARBALDEHYDE;1H-INDAZOLE-3-CARBOXALDEHYDE
- CBNumber
- CB8309369
- Molecular Formula
- C8H6N2O
- Formula Weight
- 146.15
- MOL File
- 5235-10-9.mol
1H-INDAZOLE-3-CARBALDEHYDE Property
- Melting point:
- 131-132 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
- Boiling point:
- 358.3±15.0 °C(Predicted)
- Density
- 1.368±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- crystalline powder
- pka
- 12.04±0.40(Predicted)
- color
- Light yellow
- CAS DataBase Reference
- 5235-10-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- J99710
- Product name
- 1H-Indazole-3-carbaldehyde
- Packaging
- 1g
- Price
- $23
- Updated
- 2021/12/16
- Product number
- F12293
- Product name
- 3-Formylindazole
- Purity
- 95%
- Packaging
- 5g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 144810
- Product name
- 1H-Indazole-3-carbaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $89
- Updated
- 2021/12/16
- Product number
- F12293
- Product name
- 3-Formylindazole
- Purity
- 95%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 144810
- Product name
- 1H-Indazole-3-carbaldehyde
- Purity
- 95%
- Packaging
- 5g
- Price
- $330
- Updated
- 2021/12/16
1H-INDAZOLE-3-CARBALDEHYDE Chemical Properties,Usage,Production
Antimicrobial activity
1H-Indazole-3-carbaldehyde has been shown to have antibacterial activity by inhibiting bacterial cell wall synthesis and fluorescence probe activity. It also interacts with 3-hydroxybenzoic acid, which may lead to fluorescent microscopy and efficient methods.
Synthesis
64132-13-4
5235-10-9
The general procedure for the synthesis of 3-formylindazole from 3-hydroxymethylindazole is as follows: 1. (1H-indazol-3-yl)-methanol (200 mg, 1.35 mmol) was dissolved in dichloromethane (10 mL). 2. manganese dioxide (MnO?, 1.3 g, 13.46 mmol) was added to the above solution. 3. The reaction mixture was stirred at room temperature for 16 hours. 4. 4. Upon completion of the reaction, the mixture was filtered to remove the solid catalyst. 5. The filtrate was concentrated to give 1H-indazole-3-carbaldehyde (150 mg, 76% yield). Product characterization data: - Mass spectrum (MS): m/z = 145.0 (API-). - 1H-NMR (400 MHz, DMSO-d6): δ (ppm) = 7.37 (t, 1H), 7.51 (t, 1H), 7.71 (d, 1H), 8.14 (d, 1H), 10.20 (s, 1H, aldehydic hydrogen), 14.17 (br, 1H, indazole NH).
References
[1] Patent: US2006/142247, 2006, A1. Location in patent: Page/Page column 28
[2] Patent: WO2005/9958, 2005, A1. Location in patent: Page 100-101
[3] Patent: US2005/9894, 2005, A1. Location in patent: Page 18; 27
1H-INDAZOLE-3-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
1H-INDAZOLE-3-CARBALDEHYDE Suppliers
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
View Lastest Price from 1H-INDAZOLE-3-CARBALDEHYDE manufacturers
- Product
- 1H-indazole-3-carboxaldehyde 5235-10-9
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2023-06-26