ChemicalBook > CAS DataBase List > 1H-INDAZOLE-3-CARBALDEHYDE

1H-INDAZOLE-3-CARBALDEHYDE

Product Name
1H-INDAZOLE-3-CARBALDEHYDE
CAS No.
5235-10-9
Chemical Name
1H-INDAZOLE-3-CARBALDEHYDE
Synonyms
3-Formylindazole;3-Formyl-1H-indazole;3-Indazolecarbadehyde;3-INDAZOLECARBALDEHYDE;1H-indazole-3-aldehyde;indazole-3-carbaldehyde;Indazole-3-carboxaldehyde;INDAZOLE-3-CARBOXYALDEHYDE;1H-INDAZOLE-3-CARBALDEHYDE;1H-INDAZOLE-3-CARBOXALDEHYDE
CBNumber
CB8309369
Molecular Formula
C8H6N2O
Formula Weight
146.15
MOL File
5235-10-9.mol
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1H-INDAZOLE-3-CARBALDEHYDE Property

Melting point:
131-132 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
Boiling point:
358.3±15.0 °C(Predicted)
Density 
1.368±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
crystalline powder
pka
12.04±0.40(Predicted)
color 
Light yellow
CAS DataBase Reference
5235-10-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37/39
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
J99710
Product name
1H-Indazole-3-carbaldehyde
Packaging
1g
Price
$23
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
F12293
Product name
3-Formylindazole
Purity
95%
Packaging
5g
Price
$50
Updated
2021/12/16
Matrix Scientific
Product number
144810
Product name
1H-Indazole-3-carbaldehyde
Purity
95%
Packaging
1g
Price
$89
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
F12293
Product name
3-Formylindazole
Purity
95%
Packaging
1g
Price
$15
Updated
2021/12/16
Matrix Scientific
Product number
144810
Product name
1H-Indazole-3-carbaldehyde
Purity
95%
Packaging
5g
Price
$330
Updated
2021/12/16
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1H-INDAZOLE-3-CARBALDEHYDE Chemical Properties,Usage,Production

Antimicrobial activity

1H-Indazole-3-carbaldehyde has been shown to have antibacterial activity by inhibiting bacterial cell wall synthesis and fluorescence probe activity. It also interacts with 3-hydroxybenzoic acid, which may lead to fluorescent microscopy and efficient methods.

Synthesis

64132-13-4

5235-10-9

The general procedure for the synthesis of 3-formylindazole from 3-hydroxymethylindazole is as follows: 1. (1H-indazol-3-yl)-methanol (200 mg, 1.35 mmol) was dissolved in dichloromethane (10 mL). 2. manganese dioxide (MnO?, 1.3 g, 13.46 mmol) was added to the above solution. 3. The reaction mixture was stirred at room temperature for 16 hours. 4. 4. Upon completion of the reaction, the mixture was filtered to remove the solid catalyst. 5. The filtrate was concentrated to give 1H-indazole-3-carbaldehyde (150 mg, 76% yield). Product characterization data: - Mass spectrum (MS): m/z = 145.0 (API-). - 1H-NMR (400 MHz, DMSO-d6): δ (ppm) = 7.37 (t, 1H), 7.51 (t, 1H), 7.71 (d, 1H), 8.14 (d, 1H), 10.20 (s, 1H, aldehydic hydrogen), 14.17 (br, 1H, indazole NH).

References

[1] Patent: US2006/142247, 2006, A1. Location in patent: Page/Page column 28
[2] Patent: WO2005/9958, 2005, A1. Location in patent: Page 100-101
[3] Patent: US2005/9894, 2005, A1. Location in patent: Page 18; 27

1H-INDAZOLE-3-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-INDAZOLE-3-CARBALDEHYDE Suppliers

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View Lastest Price from 1H-INDAZOLE-3-CARBALDEHYDE manufacturers

PNP Biotech Co. Ltd
Product
1H-indazole-3-carboxaldehyde 5235-10-9
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2023-06-26

5235-10-9, 1H-INDAZOLE-3-CARBALDEHYDERelated Search:

GRANISETRON IMPURITY B 7-Hydroxygranisetron 1-Methylindazole-3-carboxylic acid Granisetron hydrochloride Xinidamine Indazole-3-carboxylic acid Lonidamine 1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER 6-BROMO-1H-INDAZOLE-3-CARBALDEHYDE 5-METHYL-1H-INDAZOLE-3-CARBALDEHYDE 5-CHLORO-1H-INDAZOLE-3-CARBALDEHYDE,5-Chloro-1H-indazole-3-carbaldehyde ,97% 1-METHYL-1H-INDAZOLE-3-CARBALDEHYDE 6-NITRO-1H-INDAZOLE-3-CARBALDEHYDE 5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE, 95+%,5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE 6-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE 1-Methyl-1H-indazole-4-carbaldehyde 7-METHYL-1H-INDAZOLE-3-CARBALDEHYDE 5-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE, 95+%,5-METHOXY-1H-INDAZOLE-3-CARBALDEHYDE

  • 1H-INDAZOLE-3-CARBALDEHYDE
  • 1H-INDAZOLE-3-CARBOXALDEHYDE
  • 1H-INDAZOLE-3-CARBOXYALDEHYDE
  • 3-INDAZOLECARBALDEHYDE
  • INDAZOLE-3-CARBOXYALDEHYDE
  • Indazole-3-carboxaldehyde
  • 3-Formylindazole
  • 3-Formyl-1H-indazole
  • indazole-3-carbaldehyde
  • 1H-indazole-3-aldehyde
  • 3-Indazolecarbadehyde
  • 5235-10-9
  • 1218-36-7
  • pharmacetical