NFκB Inhibitor
- Product Name
- NFκB Inhibitor
- CAS No.
- 213546-53-3
- Chemical Name
- NFκB Inhibitor
- Synonyms
- SN50;SN50 ,S6671;NFkB Inhibitor;NF-KAPPA-B SN50;NF-κB Inhibitor, SN50;NF-KAPPAB INHIBITOR SN50;NFκB Inhibitor inhibitor;AAVALLPAVLLALLAPVQRKRQKLMP;NF-κB Inhibitor, SN50, >=97%;NF-kB Inhibitor, SN50 - 1 mg
- CBNumber
- CB6315148
- Molecular Formula
- C129H230N36O29S
- Formula Weight
- 2781.5
- MOL File
- 213546-53-3.mol
NFκB Inhibitor Property
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- form
- film
- color
- colorless
- Water Solubility
- Water : ≥ 50 mg/mL (17.98 mM)
- Sequence
- Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro
N-Bromosuccinimide Price
- Product number
- SML1471
- Product name
- SN50 trifluoroacetate salt
- Purity
- ≥95% (HPLC)
- Packaging
- 1MG
- Price
- $281
- Updated
- 2025/07/31
- Product number
- 17493
- Product name
- NF-κB Inhibitor
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $52
- Updated
- 2021/12/16
- Product number
- 17493
- Product name
- NF-κB Inhibitor
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $99
- Updated
- 2021/12/16
- Product number
- 17493
- Product name
- NF-κB Inhibitor
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $416
- Updated
- 2021/12/16
- Product number
- N392505
- Product name
- NFkappaBInhibitor
- Packaging
- 1mg
- Price
- $150
- Updated
- 2021/12/16
NFκB Inhibitor Chemical Properties,Usage,Production
Uses
NFkappaB Inhibitor is inhibits translocation of the NFκB active complex into the nucleus.
Biochem/physiol Actions
SN50 is an NF-κB cell permeable inhibitory peptide. The SN50 sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NFκB p50 linked to a peptide cell-permeabilization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). SN50 Peptide inhibits translocation of the NF-κB active complex into the nucleus.
in vivo
Treatment with SN50 accelerates the recovery of motor functional outcome from 1st to 4th day. Animals subjected to SN50 pretreatment demonstrate a significant decrease in the visuospatial learning latencies relative to the control group at 7 and 8 days post-TBI. Pretreatment with SN50 results in a significant reduction of NF-κB p65 protein levels from 6 to 48 h post-TBI and TNF-a protein levels from 12 to 48 h post-TBI[1].
IC 50
NF-κB
NFκB Inhibitor Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from NFκB Inhibitor manufacturers
- Product
- NFκB Inhibitor 213546-53-3
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-02-13