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NFκB Inhibitor

Product Name
NFκB Inhibitor
CAS No.
213546-53-3
Chemical Name
NFκB Inhibitor
Synonyms
SN50;SN50 ，S6671;NFkB Inhibitor;NF-KAPPA-B SN50;NF-κB Inhibitor, SN50;NF-KAPPAB INHIBITOR SN50;NFκB Inhibitor inhibitor;AAVALLPAVLLALLAPVQRKRQKLMP;NF-κB Inhibitor, SN50, >=97%;NF-kB Inhibitor, SN50 - 1 mg
CBNumber
CB6315148
Molecular Formula
C129H230N36O29S
Formula Weight
2781.5
MOL File
213546-53-3.mol
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NFκB Inhibitor Property

Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
-20°C
form 
film
color 
colorless
Water Solubility 
Water : ≥ 50 mg/mL (17.98 mM)
Sequence
Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1471
Product name
SN50 trifluoroacetate salt
Purity
≥95% (HPLC)
Packaging
1MG
Price
$281
Updated
2025/07/31
Cayman Chemical
Product number
17493
Product name
NF-κB Inhibitor
Purity
≥95%
Packaging
500μg
Price
$52
Updated
2021/12/16
Cayman Chemical
Product number
17493
Product name
NF-κB Inhibitor
Purity
≥95%
Packaging
1mg
Price
$99
Updated
2021/12/16
Cayman Chemical
Product number
17493
Product name
NF-κB Inhibitor
Purity
≥95%
Packaging
5mg
Price
$416
Updated
2021/12/16
TRC
Product number
N392505
Product name
NFkappaBInhibitor
Packaging
1mg
Price
$150
Updated
2021/12/16
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NFκB Inhibitor Chemical Properties,Usage,Production

Uses

NFkappaB Inhibitor is inhibits translocation of the NFκB active complex into the nucleus.

Biochem/physiol Actions

SN50 is an NF-κB cell permeable inhibitory peptide. The SN50 sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NFκB p50 linked to a peptide cell-permeabilization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). SN50 Peptide inhibits translocation of the NF-κB active complex into the nucleus.

in vivo

Treatment with SN50 accelerates the recovery of motor functional outcome from 1st to 4th day. Animals subjected to SN50 pretreatment demonstrate a significant decrease in the visuospatial learning latencies relative to the control group at 7 and 8 days post-TBI. Pretreatment with SN50 results in a significant reduction of NF-κB p65 protein levels from 6 to 48 h post-TBI and TNF-a protein levels from 12 to 48 h post-TBI[1].

IC 50

NF-κB

NFκB Inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

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NFκB Inhibitor Suppliers

China 89 Japan 3 Switzerland 1 United Kingdom 1 United States 9 Global 103
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74
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View Lastest Price from NFκB Inhibitor manufacturers

Career Henan Chemical Co
Product
NFκB Inhibitor 213546-53-3
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-13

213546-53-3, NFκB InhibitorRelated Search:

H-MET-PRO-OH NFκB Inhibitor

  • FGF-4 PRECURSOR (7-22) (HUMAN)-EBP-1 (359-368) (HUMAN)
  • FIBROBLAST GROWTH FACTOR-4 PRECURSOR (7-22) (HUMAN)-NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT (359-368) (HUMAN)
  • H-ALA-ALA-VAL-ALA-LEU-LEU-PRO-ALA-VAL-LEU-LEU-ALA-LEU-LEU-ALA-PRO-VAL-GLN-ARG-LYS-ARG-GLN-LYS-LEU-MET-PRO-OH
  • HST-1 PRECURSOR (7-22) (HUMAN)-DNA-BINDING FACTOR KBF1 (359-368) (HUMAN)
  • AAVALLPAVLLALLAPVQRKRQKLMP
  • NF-KAPPA-B SN50
  • NF-KAPPA-B SN50, CELL-PERMEABLE INHIBITOR PEPTIDE
  • NF-KAPPAB SN50, CELL-PERMEABLE INHIBITORY PEPTIDE
  • NF-KAPPAB INHIBITOR SN50
  • NUCLEAR FACTOR NF-B INHIBITOR SN50
  • NUCLEAR FACTOR NF-KAPPA-B INHIBITOR SN50
  • SN50
  • FGF-4 Precursor (7-22) (huMan)-EBP-1 (359-368) (huMan), HST-1 Precursor (7-22) (huMan)-DNA-Binding Factor KBF1 (359-368) (huMan), Fibroblast Growth Factor-4 Precursor (7-22) (huMan)-Nuclear Factor NF-ΚB p105 Subunit (359-368) (huMan) TFA
  • NF-κB Inhibitor, SN50, >=97%
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  • NFκB Inhibitor inhibitor
  • NF-kB Inhibitor, SN50 - 1 mg
  • SN50 ，S6671
  • 213546-53-3
  • C129H230N36O29S