ChemicalBook > CAS DataBase List > NFκB Inhibitor

NFκB Inhibitor

Product Name: NFκB Inhibitor
CAS No.: 213546-53-3
Chemical Name: NFκB Inhibitor
Synonyms: SN50;SN50 ，S6671;NFkB Inhibitor;NF-KAPPA-B SN50;NF-κB Inhibitor, SN50;NF-KAPPAB INHIBITOR SN50;NFκB Inhibitor inhibitor;AAVALLPAVLLALLAPVQRKRQKLMP;NF-κB Inhibitor, SN50, >=97%;NF-kB Inhibitor, SN50 - 1 mg
CBNumber: CB6315148
Molecular Formula: C129H230N36O29S
Formula Weight: 2781.5
MOL File: 213546-53-3.mol

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NFκB Inhibitor Property

Density: 1.36±0.1 g/cm3(Predicted)
storage temp.: -20°C
form: film
color: colorless
Water Solubility: Water : ≥ 50 mg/mL (17.98 mM)
Sequence: Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1471
Product name: SN50 trifluoroacetate salt
Purity: ≥95% (HPLC)
Packaging: 1MG
Price: $281
Updated: 2025/07/31

Cayman Chemical

Product number: 17493
Product name: NF-κB Inhibitor
Purity: ≥95%
Packaging: 500μg
Price: $52
Updated: 2021/12/16

Cayman Chemical

Product number: 17493
Product name: NF-κB Inhibitor
Purity: ≥95%
Packaging: 1mg
Price: $99
Updated: 2021/12/16

Cayman Chemical

Product number: 17493
Product name: NF-κB Inhibitor
Purity: ≥95%
Packaging: 5mg
Price: $416
Updated: 2021/12/16

TRC

Product number: N392505
Product name: NFkappaBInhibitor
Packaging: 1mg
Price: $150
Updated: 2021/12/16

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NFκB Inhibitor Chemical Properties,Usage,Production

Uses

NFkappaB Inhibitor is inhibits translocation of the NFκB active complex into the nucleus.

Biochem/physiol Actions

SN50 is an NF-κB cell permeable inhibitory peptide. The SN50 sequence contains the nuclear localization sequence (NLS residues 360-369) of the transcription factor NFκB p50 linked to a peptide cell-permeabilization sequence, the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF). SN50 Peptide inhibits translocation of the NF-κB active complex into the nucleus.

in vivo

Treatment with SN50 accelerates the recovery of motor functional outcome from 1st to 4th day. Animals subjected to SN50 pretreatment demonstrate a significant decrease in the visuospatial learning latencies relative to the control group at 7 and 8 days post-TBI. Pretreatment with SN50 results in a significant reduction of NF-κB p65 protein levels from 6 to 48 h post-TBI and TNF-a protein levels from 12 to 48 h post-TBI^[1].

IC 50

NF-κB

NFκB Inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from NFκB Inhibitor manufacturers

Career Henan Chemical Co

Product: NFκB Inhibitor 213546-53-3
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

213546-53-3, NFκB InhibitorRelated Search:

H-MET-PRO-OH NFκB Inhibitor

FGF-4 PRECURSOR (7-22) (HUMAN)-EBP-1 (359-368) (HUMAN)

FIBROBLAST GROWTH FACTOR-4 PRECURSOR (7-22) (HUMAN)-NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT (359-368) (HUMAN)

H-ALA-ALA-VAL-ALA-LEU-LEU-PRO-ALA-VAL-LEU-LEU-ALA-LEU-LEU-ALA-PRO-VAL-GLN-ARG-LYS-ARG-GLN-LYS-LEU-MET-PRO-OH

HST-1 PRECURSOR (7-22) (HUMAN)-DNA-BINDING FACTOR KBF1 (359-368) (HUMAN)

AAVALLPAVLLALLAPVQRKRQKLMP

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NF-κB Inhibitor, SN50, >=97%

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NFκB Inhibitor inhibitor

NF-kB Inhibitor, SN50 - 1 mg

SN50 ，S6671

213546-53-3

C129H230N36O29S