INCB28060 Dihydrochloride

Product Name: INCB28060 Dihydrochloride
CAS No.: 1197376-85-4
Chemical Name: INCB28060 Dihydrochloride
Synonyms: INC-280 2HCl;INCB28060 2HCl;Capmatinib 2HCl;INCB28060 Dihydrochloride;Capmatinib Dihydrochloride;2-Fluoro-N-methyl-4-[7-[(quinolin-6-yl)methyl]imidazo[1,2-b]-[1,2,4]triazin-2-yl]benzamide Dihydrochloride;Benzamide, 2-fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]-, hydrochloride (1:2);Capmatinib,Apoptosis,c-Met/HGFR,INC 280,H441,INCB28060,INC280,orally active,Capmatinib 2HCl,INCB-28060,SNU-5,INC-280,Inhibitor,S114,INCB 28060,inhibit,U-87MG,ATP competitive,Balb/c nu/nu mice
CBNumber: CB63167063
Molecular Formula: C23H18ClFN6O
Formula Weight: 448.89
MOL File: 1197376-85-4.mol

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H371May cause damage to organs

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P309+P311IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

INCB28060 Dihydrochloride Chemical Properties,Usage,Production

Description

INCB28060 Dihydrochloride is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.

Uses

INCB28060 dihydrochloride exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines. As a result, INCB 28060 potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis in vitro.

INCB28060 Dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

INCB28060 Dihydrochloride Suppliers

China 57 United States 1 Global 58

Anqing Benro pharmachem Technology Co.,Ltd.

Tel: 05565209906 15391842992
Email: 794263564@qq.com
Country: China
ProdList: 111
Advantage: 58

Tianjin Zhongcheng Mingyuan Technology Co., Ltd.

Tel: 13302022156
Fax: -
Email: 3506745780@qq.com
Country: China
ProdList: 171
Advantage: 58

Suzhou Ryan Pharmaceutical Technology Co., Ltd.

Tel: 0512-68780025,68780026 18962125825
Email: sales@ryanchem.com
Country: China
ProdList: 161
Advantage: 62

Shanghai Arbor Chemical Co., Ltd.

Tel: 021-021-60451683 15021268886
Fax: +86-21-60451682
Email: sales@arborchemical.com
Country: China
ProdList: 922
Advantage: 55

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7892
Advantage: 56

Biyu Biotechnology (Shanghai) Co., ltd

Tel: 021-26018599
Country: China
ProdList: 270
Advantage: 56

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-50266790 Q3382968513
Fax: QQ3382968513
Email: Hailey@shsendpharm.com
Country: China
ProdList: 3170
Advantage: 55

Cangzhou Enke Pharma-tech Co., Ltd.

Tel: 0317-5296180 15533709196
Fax: 0317-5106596
Email: sale@enkepharma.com
Country: China
ProdList: 1649
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Shanghai Jinsheng Pharmaceutical Co., Ltd.

Tel: 13651960330
Email: xiangfeixia@jspharmatech.com
Country: China
ProdList: 311
Advantage: 58

1197376-85-4, INCB28060 DihydrochlorideRelated Search:

Dabrafenib Trametinib Regorafenib Neratinib Poziotinib (HM781-36B) Dacomitinib (PF299804) Cediranib Maleate Crizotinib Afatinib (BIBW 2992) Lorlatinib (PF-06463922) AZD-9291 Olaparib Vandetanib Capmatinib lenvatinib Mesylate Afatinib dimaleate Cabozantinib Malate Nintedanib Ethanesulfonate Salt

2-Fluoro-N-methyl-4-[7-[(quinolin-6-yl)methyl]imidazo[1,2-b]-[1,2,4]triazin-2-yl]benzamide Dihydrochloride

INCB28060 2HCl

INCB28060 Dihydrochloride

Capmatinib 2HCl

INC-280 2HCl

Capmatinib Dihydrochloride

Benzamide, 2-fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]-, hydrochloride (1:2)

Capmatinib,Apoptosis,c-Met/HGFR,INC 280,H441,INCB28060,INC280,orally active,Capmatinib 2HCl,INCB-28060,SNU-5,INC-280,Inhibitor,S114,INCB 28060,inhibit,U-87MG,ATP competitive,Balb/c nu/nu mice

1197376-85-4

API