GSK864

ChemicalBook > CAS DataBase List > GSK864

Product Name: GSK864
CAS No.: 1816331-66-4
Chemical Name: GSK864
Synonyms: GSK864;GSK864,GSK-864;GSK864 >=98% (HPLC);1H-Pyrazolo[4,3-c]pyridine-3,7-dicarboxamide, 1-[(4-fluorophenyl)methyl]-4,5,6,7-tetrahydro-N3-(4-methoxy-3,5-dimethylphenyl)-7-methyl-5-(1H-pyrrol-2-ylcarbonyl)-, (7S)-
CBNumber: CB63171695
Molecular Formula: C30H31FN6O4
Formula Weight: 558.6
MOL File: 1816331-66-4.mol

Less

GSK864 Property

Boiling point:: 782.9±60.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF:20.0(Max Conc. mg/mL);35.8(Max Conc. mM)
DMSO:60.0(Max Conc. mg/mL);107.41(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);35.8(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);0.9(Max Conc. mM)
pka: 11.73±0.70(Predicted)
form: powder
color: white to beige
optical activity: [α]/D -66 to -76°, c = 0.5 in methanol

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1757
Product name: GSK864
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $312
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML1757
Product name: GSK864
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $1210
Updated: 2023/06/20

Cayman Chemical

Product number: 18762
Product name: GSK864
Purity: ≥98%
Packaging: 500μg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 18762
Product name: GSK864
Purity: ≥98%
Packaging: 1mg
Price: $65
Updated: 2024/03/01

Cayman Chemical

Product number: 18762
Product name: GSK864
Purity: ≥98%
Packaging: 5mg
Price: $266
Updated: 2024/03/01

Less

GSK864 Chemical Properties,Usage,Production

Biochem/physiol Actions

GSK864 is a cell penetrant, potent and selective allosteric inhibitor of isocitrate dehydrogenase 1 (IDH1) that potently inhibits intracellular 2-hydroxyglutarate (2-HG) production in HT-1080 cells. It appears that GSK864 binds to an allosteric binding site and locks WT and mutant IDH1s in a catalytically inactive conformation. GSK864 is a highly bioavailable analog of GSK321. For full characterization details, please visit the GSK864 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc

GSK864 Preparation Products And Raw materials

Raw materials

Preparation Products

Less

GSK864 Suppliers

China 48 United States 6 USA 1 Global 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4182
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8015
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2985
Advantage: 58

Hangzhou Synstar pharmaceutical Technology CO.,Ltd

Tel: 0571-85361029
Fax: 0571-85361029
Email: synstar518@163.com
Country: China
ProdList: 1991
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 15093356674;
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30255
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9414
Advantage: 58

Changzhou Chenhong Biotechnology Co., Ltd.

Tel: 0519-85788828 13775037613
Email: sales@chemrenpharm.com
Country: China
ProdList: 3574
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

Shanghai Zeye Biotechnology Co., Ltd.

Tel: 021-61998551 13122364865
Email: sale1@shzysw.net
Country: China
ProdList: 9771
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd

Tel: 15317229551
Fax: QQ:3607245178
Email: 15151849396@163.com
Country: China
ProdList: 997
Advantage: 58

ShangHai ChuanQian Chemcial Technique Centre

Tel: 15869524721
Email: 3525679403@qq.com
Country: China
ProdList: 3614
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8141
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44941
Advantage: 58

Nantong Hi-Future Biotechnology Co., Ltd

Tel: 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 3061
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 29778
Advantage: 58

Hubei Kele Fine Chemical Co., Ltd

Tel: 027-59101668 19945030958
Fax: 027-59101668
Email: 2881924765@qq.com
Country: China
ProdList: 7973
Advantage: 58

Wuhan Augda Biotechnology Co., Ltd

Tel: 15071299552
Fax: QQ:262933239
Email: 262933239@qq.com
Country: China
ProdList: 6637
Advantage: 58

Chengdu PEIP Pharmaceutical Technology Co., LTD.

Tel: 028-61715638 18011352545
Fax: QQ：1242335375
Email: 1242335275@qq.com
Country: China
ProdList: 476
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6749
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24017
Advantage: 58

Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd

Tel: 024-024-88590548 18341751992
Email: 757984502@qq.com
Country: China
ProdList: 888
Advantage: 58

Shanghai Yiyan Biotechnology Co. , Ltd.

Tel: 021-69985186 13611928337
Email: 3427709316@qq.com
Country: China
ProdList: 7984
Advantage: 58

Wuhan Jingkangen Biomedical Technology Co., Ltd

Tel: 13720134139 13720134139
Email: orders@jknbiochem.com
Country: China
ProdList: 5279
Advantage: 58

Beijing Keyi Tongda Technology Development Co., Ltd

Tel: 13681252203
Email: kytd20@sina.com
Country: China
ProdList: 1285
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29990
Advantage: 58

Shenzhen Xingyue Biotechnology Co., Ltd

Tel: 18124513697; 18124513697
Fax: 18822823697
Email: jjj18822823697@163.com
Country: China
ProdList: 1407
Advantage: 58

ZhengZhou Edward Biology Co.,Ltd

Tel: 13298105281 13298105281
Email: 1522334715@qq.com
Country: China
ProdList: 7495
Advantage: 58

Changsha Fuzhen Biotechnology Co.，LTD

Tel: 0731-18670069958 18670069958
Email: 184792226@qq.com
Country: China
ProdList: 3060
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9180
Advantage: 58

Olix (Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 17316404525
Email: 209533805@qq.com
Country: China
ProdList: 9620
Advantage: 58

Wuhan Jingkang en Biomedical Technology Co., Ltd

Tel: +8613720134139
Email: orders@jknbiochem.com
Country: China
ProdList: 4691
Advantage: 58

Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd

Tel: +86-18341751992 +86-15382112998
Email: 757984502@qq.com
Country: China
ProdList: 892
Advantage: 58

Wuhan Topule Biopharmaceutical Co., Ltd

Tel: +8618327326525
Email: masar@topule.com
Country: China
ProdList: 8474
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49739
Advantage: 58

Nantong HI-FUTURE Biology Co., Ltd.

Tel: +undefined18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 3136
Advantage: 58

Beijing Baiao Laibo Technology Co., Ltd.

Tel: --
Fax: --
Email: 570202610@qq.com
Country: CHINA
ProdList: 6851
Advantage: 58

Shanghai Hao Test Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: prbiological@sohu.com
Country: CHINA
ProdList: 6846
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6661
Advantage: 58

Shanghai Weiwei Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: sales@wheybio.com
Country: CHINA
ProdList: 4398
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6846
Advantage: 58

Guangzhou Weijia Technology Co., Ltd.

Tel: --
Fax: --
Email: WHIGA22@126.COM
Country: CHINA
ProdList: 6748
Advantage: 58

Shanghai Yuqi Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 847627550@qq.com
Country: CHINA
ProdList: 6087
Advantage: 58

Wuhan Boot Biotechnology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6829
Advantage: 58

1816331-66-4, GSK864Related Search:

GSK2837808A GSK6853 GSK-A1 S)-1-(sec-butyl)-N-((4,6-diMethyl-2-oxo-1,2-dihydropyridin-3-yl)Methyl)-3-Methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxaMide GSK484 GSK J4 HCl GSK 2334470 GSK2982772 GSK2636771 Benzeneacetamide, α-[[6-(4-amino-1-piperidinyl)-3,5-dicyano-4-ethyl-2-pyridinyl]thio]- GSK778 N-(6-Fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydro-3-pyridinecarboxamide GSK 2033 2-((4-(benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl dihydrogen phosphate N-((S)-1-(4-((S)-2-(2,4-dichlorophenylsulfonaMido)-3-hydroxypropanoyl)piperazin-1-yl)-4-Methyl-1-oxopentan-2-yl)benzo[b]thiophene-2-carboxaMide GSK-2256098 GSK215

GSK864

1H-Pyrazolo[4,3-c]pyridine-3,7-dicarboxamide, 1-[(4-fluorophenyl)methyl]-4,5,6,7-tetrahydro-N3-(4-methoxy-3,5-dimethylphenyl)-7-methyl-5-(1H-pyrrol-2-ylcarbonyl)-, (7S)-

GSK864 >=98% (HPLC)

GSK864,GSK-864

1816331-66-4

C30H31FN6O4