2-CHLORO-3-CYANOQUINOLINE
- Product Name
- 2-CHLORO-3-CYANOQUINOLINE
- CAS No.
- 95104-21-5
- Chemical Name
- 2-CHLORO-3-CYANOQUINOLINE
- Synonyms
- AKOS BB-7566;2-CHLORO-3-CYANOQUINOLINE;2-Chloro-3-quinolinecarbonitrile;2-CHLOROQUINOLINE-3-CARBONITRILE;3-Quinolinecarbonitrile,2-chloro-;2-CHLORO-3-CYANOQUINOLINE ISO 9001：2015 REACH
- CBNumber
- CB6324593
- Molecular Formula
- C10H5ClN2
- Formula Weight
- 188.61
- MOL File
- 95104-21-5.mol
2-CHLORO-3-CYANOQUINOLINE Property
- Melting point:
- 164-168 °C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C10H5ClN2/c11-10-8(6-12)5-7-3-1-2-4-9(7)13-10/h1-5H
- InChIKey
- UGTRDMPALMEDBU-UHFFFAOYSA-N
- SMILES
- C1C=C2C(N=C(Cl)C(C#N)=C2)=CC=1
N-Bromosuccinimide Price
- Product number
- 687790
- Product name
- 2-Chloroquinoline-3-carbonitrile
- Purity
- 97%
- Packaging
- 250mg
- Price
- $101
- Updated
- 2023/01/07
- Product number
- 687790
- Product name
- 2-Chloroquinoline-3-carbonitrile
- Purity
- 97%
- Packaging
- 1g
- Price
- $196
- Updated
- 2023/01/07
- Product number
- C385125
- Product name
- 2-Chloroquinoline-3-carbonitrile
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C385125
- Product name
- 2-Chloroquinoline-3-carbonitrile
- Packaging
- 500mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- OR307835
- Product name
- 2-Chloroquinoline-3-carbonitrile
- Packaging
- 1g
- Price
- $269
- Updated
- 2021/12/16
2-CHLORO-3-CYANOQUINOLINE Chemical Properties,Usage,Production
Synthesis
73568-25-9
95104-21-5
General procedure for the synthesis of 2-chloro-3-cyanoquinoline from 2-chloro-3-quinolinecarboxaldehyde: 2-chloroquinoline-3-carboxaldehyde (0.01 mol) was suspended in 30% ammonia (30 mL) and stirred at room temperature for 5 min to form a turbid solution. Stirring was continued at 0 °C and ceric ammonium nitrate (0.01 mol) was slowly added. The reaction process was monitored by thin layer chromatography (TLC) and the reaction time was about 10-15 minutes. After completion of the reaction, the reaction mixture was extracted with a solvent mixture of chloroform-ethyl acetate (5:3 v/v). The organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was recrystallized by ethanol to give pure 2-chloro-3-cyanoquinoline as light yellow crystals in 82% yield.
References
[1] Synlett, 2009, # 20, p. 3378 - 3382
[2] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005, vol. 44, # 9, p. 1868 - 1875
[3] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006, vol. 45, # 1, p. 292 - 296
[4] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2009, vol. 48, # 1, p. 152 - 154
[5] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 3, p. 602 - 611
2-CHLORO-3-CYANOQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-CHLORO-3-CYANOQUINOLINE manufacturers
- Product
- 2-CHLORO-3-CYANOQUINOLINE 95104-21-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- KG/T
- Release date
- 2019-12-20