5-Fluoroorotic acid

Product Name: 5-Fluoroorotic acid
CAS No.: 703-95-7
Chemical Name: 5-Fluoroorotic acid
Synonyms: foa;fo;5-FOA;5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyriMidine-4-carboxylic acid;5' FOA;ro2-9945;nsc31712;Fluoxydin;ent-26398;WR 152520
CBNumber: CB6325772
Molecular Formula: C5H3FN2O4
Formula Weight: 174.09
MOL File: 703-95-7.mol

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5-Fluoroorotic acid Property

Melting point:: 278 °C (dec.)(lit.)
Boiling point:: 143°C (rough estimate)
Density: 1.6154 (estimate)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: NH₄OH 4 M: 50 mg/mL, clear, faintly yellow
pka: 2.04±0.20(Predicted)
form: solid
color: Pale yellow
Merck: 14,4176
InChI: InChI=1S/C5H3FN2O4/c6-1-2(4(10)11)7-5(12)8-3(1)9/h(H,10,11)(H2,7,8,9,12)
InChIKey: LODRRYMGPWQCTR-UHFFFAOYSA-N
SMILES: C1(=O)NC(=O)C(F)=C(C(O)=O)N1
CAS DataBase Reference: 703-95-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-36-36/37/39-27
WGK Germany: 3
RTECS: UV7800000
F: 10
HazardClass: IRRITANT
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: F0382
Product name: 5-Fluoroorotic Acid Monohydrate
Purity: >95.0%(HPLC)(T)
Packaging: 1g
Price: $49
Updated: 2025/07/31

TCI Chemical

Product number: F0382
Product name: 5-Fluoroorotic Acid Monohydrate
Purity: >95.0%(HPLC)(T)
Packaging: 100mg
Price: $16
Updated: 2025/07/31

Apolloscientific

Product number: PC408010
Product name: 5-Fluorooroticacid
Packaging: 1g
Price: $42
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H53-3-25
Product name: 5-Fluoroorotic acid
Purity: 99%
Packaging: 1g
Price: $55
Updated: 2021/12/16

Apolloscientific

Product number: PC408010
Product name: 5-Fluorooroticacid
Packaging: 5g
Price: $77
Updated: 2021/12/16

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5-Fluoroorotic acid Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Crystalline Solid

Uses

Useful in the selection of orotidine-5′-phosphate decarboxylase mutants of Saccharomyces cerevisiae.

Uses

5-FOA(5-Fluoroorotic acid ) has become a valuable tool for research in the field of molecular genetics. It has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5'-phosphate decarboxylase deficient. 5-FOA is coverted to 5-fluorouridine monophosphate (5-FUMP) in yeast cells, which can become incorporated into RNA or metabolized to the highly toxic 5-fluoro-2’-deoxyuridine monophosphate (5-FdUMP). 5-FdUMP is a potent inhibitor of thymidylate synthase (TS), causing the cessation of DNA synthesis. More recently, 5-FOA has been shown to possess potent antimalarial activity against both chloroquine-susceptible and chloroquine-resistant clones of Plasmodium falciparum. Studies indicate that TS is the primary target of 5-FOA in malarial parasites. The combination of 5-FOA and uracil has been effective in treating mice infected with Plasmodium yoelli. 5-FOA may also have potential in the treatment of human malarial infections when used in combination with other agents.

5-Fluoroorotic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Fluoroorotic acid Suppliers

Canada 5 China 307 Europe 2 France 1 Germany 7 India 8 Italy 1 Japan 2 Russia 1 Slovakia 1 Switzerland 5 The Netherlands 1 Ukraine 1 United Kingdom 22 United States 40 Global 404

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View Lastest Price from 5-Fluoroorotic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 5-Fluoroorotic acid 703-95-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-18

Hebei Chuanghai Biotechnology Co,.LTD

Product: 5-Fluoroorotic Acid 703-95-7
Price: US $10.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10 ton
Release date: 2024-08-21

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Fluoroorotic acid 703-95-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

703-95-7, 5-Fluoroorotic acid Related Search:

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1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-4-pyrimidinecarboxylicaci

1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-4-pyrimidinecarboxylicacid

5-fluoro-2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate

nsc31712

ro2-9945

2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid

5-FLUOROURACIL-4-CARBOXYLIC ACID

5' FOA

5-FOA

5-FLUOROOROTIC ACID

5-FLUORO-2,6-DIOXO-3H-PYRIMIDINE-4-CARBOXYLIC ACID

5-FLUOROORTIC ACID

5-Fluoroorotic

Fluoxydin

Fluoroorotic-Acid (5' FOA)

5-fluorouracil-6-carboxylic acid

5-Fluoroorotic acid monohydrate 98%

5-Fluorooroticacidmonohydrate98%

RARECHEM AH BS 0043

5-FLUOROOROTIC ACID HYDRATE 99%

4-PYRIMIDINECARBOXYLICACID,5-FLUORO-1,2,3,6-TETRAHYDRO-2,6-DIOXO

5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylicaci

5-fluoroorotate

5-fluoro-oroticaci

ent-26398

fluorooroticacid

fo

foa

4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-

WR 152520

5-Fluoro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid

5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid

5-Fluoroorotic acid anhydrous

5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyriMidine-4-carboxylic acid

5-Fluoroorotic acid,5-FOA

5-Fluoroorotic Acid&nbsp

5-Fluoroorotic acid, 98.0%+

5-Fluoroorotic acid hydrate AldrichCPR

2,6-Dihydroxy-5-fluor-pyrimidin-4-carbonsure 5-Fluor-uracil-4-carbonsure

5-FOA, 5-Fluoroorotic acid

5-FluorooroticAcidMonohydrate&gt

uoroorotic acid hydrate

5-Fluoroorotic Acid (5-FOA) for molecular biology, 98%

5-fluorowhey acid

5-Fluoroorotic acid, 10 mM in DMSO

5-Fluoroorotic acid potassium salt

703-95-7

C5H5FN2O5H2O

C5H5FN2O5

C5H3FN2O4.H2O

C5H3FN2O4

C5H3FN2O4xH2O

Activity

Fluorogenic

pyrimidine

Fluorine series

Nucleotides and Nucleosides

Biochemistry