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Triethylene glycol dimethyl ether

Product Name
Triethylene glycol dimethyl ether
CAS No.
112-49-2
Chemical Name
Triethylene glycol dimethyl ether
Synonyms
TRIGLYME;2,5,8,11-TETRAOXADODECANE;1,2-BIS(2-METHOXYETHOXY)ETHANE;DIMETHYLTRIGLYCOL;glyme4;Glyme-3;riglyme;ansulether161;dimethyltrigol;methyltriglyme
CBNumber
CB6326946
Molecular Formula
C8H18O4
Formula Weight
178.23
MOL File
112-49-2.mol
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Triethylene glycol dimethyl ether Property

Melting point:
−45 °C(lit.)
Boiling point:
216 °C(lit.)
Density 
0.986 g/mL at 25 °C(lit.)
vapor density 
>4.7 (vs air)
vapor pressure 
1.2 hPa (20 °C)
refractive index 
n20/D 1.423(lit.)
Flash point:
231 °F
storage temp. 
Store below +30°C.
solubility 
>1000g/l soluble
form 
Liquid
color 
APHA: ≤20
explosive limit
0.7%(V)
Water Solubility 
Soluble
Sensitive 
Hygroscopic
Merck 
14,9692
BRN 
1700630
Dielectric constant
7.5
InChIKey
YFNKIDBQEZZDLK-UHFFFAOYSA-N
LogP
-0.52 at 20℃
CAS DataBase Reference
112-49-2(CAS DataBase Reference)
NIST Chemistry Reference
2,5,8,11-Tetraoxadodecane(112-49-2)
EPA Substance Registry System
Triethylene glycol dimethyl ether (112-49-2)
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Safety

Hazard Codes 
T
Risk Statements 
61-19-62
Safety Statements 
53-45
WGK Germany 
1
RTECS 
XF0665000
3
Autoignition Temperature
375 °F
TSCA 
Yes
HS Code 
29094990
Toxicity
LD50 orally in Rabbit: 5390 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T59803
Product name
Triethylene glycol dimethyl ether
Purity
ReagentPlus , 99%
Packaging
250g
Price
$77.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.08249
Product name
Triethylene glycol dimethyl ether
Purity
(stabilised) for synthesis
Packaging
250ML
Price
$48.8
Updated
2024/03/01
Sigma-Aldrich
Product number
05284
Product name
Triethylene glycol dimethyl ether
Purity
analytical standard
Packaging
50mg
Price
$86.2
Updated
2022/05/15
TCI Chemical
Product number
B0496
Product name
Triethylene Glycol Dimethyl Ether (stabilized with BHT)
Purity
>99.0%(GC)
Packaging
25g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
B0496
Product name
Triethylene Glycol Dimethyl Ether (stabilized with BHT)
Purity
>99.0%(GC)
Packaging
500g
Price
$68
Updated
2024/03/01
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Triethylene glycol dimethyl ether Chemical Properties,Usage,Production

Chemical Properties

Water-white liquid; mild ether odor. D 0.9862 (20/20C), refr index 1.4233 (20C), flash p 232F (111C), bp 216.0C (760mmHg), 153.6C (100 mm Hg), fp ?46C. Completely soluble in water and hydrocarbons at 20C. May contain peroxides. Combustible.

Uses

Triethylene glycol dimethyl ether is used as a solvent for gases and coupling immiscible liquid. It is also used to prepare perfluoro-triethyleneglycoldimethylether.

Uses

Triethylene glycol dimethyl ether may be used as an analytical standard for the quantification of the analyte in water samples using in vitro bioassays and chemical screening technique.

Uses

Labelled Triglyme. It is used as a solvent.

Definition

ChEBI: A polyether that consists of dodecane in which the carbon atoms at positions 2, 5, 8 and 11 are replaced by oxygen atoms.

Application

Triethylene glycol dimethyl ether is a member of the glycol ether class of industrial solvents. These solvents are widely used to manufacture protective coatings such as lacquers, metal coatings, baking enamels, phenolic varnishes, epoxy resin coatings, and alkyl resins[1].

Reactivity Profile

TRIETHYLENE GLYCOL DIMETHYL ETHER forms explosive peroxides on prolonged exposure to air. Its decomposition products may be sensitive to shock. The bulk chemical is stable for 2 weeks at temperatures up to 140° F when protected from light. TRIETHYLENE GLYCOL DIMETHYL ETHER is incompatible with strong oxidizers. TRIETHYLENE GLYCOL DIMETHYL ETHER is also incompatible with strong acids. TRIETHYLENE GLYCOL DIMETHYL ETHER may react with peroxides, oxygen, nitric acid and sulfuric acid. .

Flammability and Explosibility

Non flammable

Toxicology

Triethylene glycol dimethyl ether (triEGdiME) is a widely used organic solvent. It is structurally related to several compounds that produce reproductive and developmental toxicity, including teratogenicity in laboratory animals. In the present studies, triEGdiME (0, 75, 125, 175, or 250 mg/kg/day) is administered by gavage in distilled water to timed-pregnant New Zealand white rabbits (15-25 dams/group) during major organogenesis [Gestational Days (gd) 6-19]. In the triEGdiME study, clinical signs of toxicity were minimal, and there was no increased maternal mortality. Maternal body weight and gravid uterine weight were significantly reduced at 250 mg/kg/day, whereas maternal weight gain during treatment was significant. They were depressed at doses of 175 mg/kg/day and above. Prenatal mortality was significantly increased at 250 mg triEGdiME/kg/day. TriEGdiME at doses of 175 and 250 mg/kg/day caused a significant increase in the incidence of malformed fetuses per litter. Malformations noted most frequently in fetuses of normal size included anonychia (missing toenails with no digital abnormalities), abnormally small spleen, and hydronephrosis[1].

Purification Methods

Reflux it with, and distil it from sodium hydride or LiAlH4. [Beilstein 1 IV 2401.]

Triethylene glycol dimethyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

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Triethylene glycol dimethyl ether Suppliers

Anhui Lixing Chemical Co., Ltd.
Tel
+86-0563-8152601 +86-13805622345
Fax
0563-8167310
Email
zhlh@lixingchem.com
Country
China
ProdList
14
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
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61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
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View Lastest Price from Triethylene glycol dimethyl ether manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Triethylene glycol dimethyl ether 112-49-2
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Hebei Chuanghai Biotechnology Co,.LTD
Product
TRIETHYLENE GLYCOL DIMETHYL ETHER 112-49-2
Price
US $10.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000kg
Release date
2024-08-21
Anhui lixing chemical co.,ltd
Product
TRIETHYLENE GLYCOL DIMETHYL ETHER 112-49-2
Price
US $0.00/kg
Min. Order
200kg
Purity
99.0%MIN
Supply Ability
2000tons
Release date
2023-08-03

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