ETHYL 4-METHOXY-3-OXO-BUTANOATE
- Product Name
- ETHYL 4-METHOXY-3-OXO-BUTANOATE
- CAS No.
- 66762-68-3
- Chemical Name
- ETHYL 4-METHOXY-3-OXO-BUTANOATE
- Synonyms
- ETHYL 4-METHOXYACETOACETATE;ETHYL 4-METHOXY-3-OXO-BUTANOATE;Ethyl 4-methoxy-3-oxobutanoate 98%;4-methoxy-acetoacetic acid ethyl ester;4-Methoxy-3-oxo-butanoic acid ethyl ester;Butanoic acid, 4-methoxy-3-oxo-, ethyl ester;ETHYL 4-METHOXY-3-OXO-BUTANOATE ISO 9001：2015 REACH;Ethyl 4-methoxy-3-oxobutanoate, Ethyl 4-methoxy-3-oxobutryate
- CBNumber
- CB6330215
- Molecular Formula
- C7H12O4
- Formula Weight
- 160.17
- MOL File
- 66762-68-3.mol
ETHYL 4-METHOXY-3-OXO-BUTANOATE Property
- Boiling point:
- 68-71 °C(Press: 5 Torr)
- Density
- 1.060±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 9.90±0.46(Predicted)
- Appearance
- Colorless to light yellow Liquid
- InChI
- InChI=1S/C7H12O4/c1-3-11-7(9)4-6(8)5-10-2/h3-5H2,1-2H3
- InChIKey
- CMKOJBYFNYDATH-UHFFFAOYSA-N
- SMILES
- C(OCC)(=O)CC(=O)COC
Safety
- HS Code
- 2918999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- B440330
- Product name
- ethyl4-methoxy-3-oxobutanoate
- Packaging
- 100mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 0252AC
- Product name
- Ethyl4-methoxy-3-oxobutanoate
- Packaging
- 5g
- Price
- $399
- Updated
- 2021/12/16
- Product number
- CHM0014360
- Product name
- ETHYL 4-METHOXY-3-OXO-BUTANOATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $998.08
- Updated
- 2021/12/16
- Product number
- J54802
- Product name
- Ethyl4-methoxy-3-oxobutanoate
- Packaging
- 25g
- Price
- $1046
- Updated
- 2021/12/16
- Product number
- 0252AC
- Product name
- Ethyl4-methoxy-3-oxobutanoate
- Packaging
- 25g
- Price
- $1397
- Updated
- 2021/12/16
ETHYL 4-METHOXY-3-OXO-BUTANOATE Chemical Properties,Usage,Production
Synthesis
67-56-1
638-07-3
66762-68-3
NaH (7.71 g, 192.7 mmol) was suspended in DMF (110 mL) and cooled to 0°C in an ice bath. A solution of MeOH (2.64 g, 82.5 mmol) in DMF (55 mL) was slowly added dropwise. After the dropwise addition, stirring was continued for 30 min at 0 °C. Subsequently, a DMF (55 mL) solution of ethyl 4-chloroacetoacetate (9.54 g, 57.9 mmol) was added slowly dropwise at 0 °C. After completion of the dropwise addition, the reaction mixture was slowly warmed to room temperature and stirred for 16 hours. After completion of the reaction, the reaction mixture was diluted with 1N HCl (400 mL) and extracted with MTBE (250 mL x 3). The organic phases were combined, washed with H2O (200 mL × 5), dried over anhydrous Na2SO4, filtered and concentrated. Finally, it was purified by silica gel column chromatography (eluent ratio PE:EA = 10:1) to afford ethyl 4-methoxy-3-oxobutanoate (1.4 g, 15.1% yield) as a light yellow oil.
References
[1] Patent: JP2015/214548, 2015, A. Location in patent: Paragraph 0992; 0993
[2] Patent: CN105481694, 2016, A. Location in patent: Paragraph 0015; 0016; 0017; 0018; 0019; 0020; 0021 - 0023
ETHYL 4-METHOXY-3-OXO-BUTANOATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ETHYL 4-METHOXY-3-OXO-BUTANOATE manufacturers
- Product
- Ethyl 4-methoxy-3-oxobutanoate 66762-68-3
- Price
- US $0.00-0.00/KG
- Min. Order
- 10g
- Purity
- 99.0%+
- Supply Ability
- 100 tons
- Release date
- 2019-12-25
- Product
- ethyl 4-methoxy-3-oxobutanoate 66762-68-3
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1KG
- Purity
- 99.0%+
- Supply Ability
- 100 tons
- Release date
- 2020-01-14
- Product
- ETHYL 4-METHOXY-3-OXO-BUTANOATE 66762-68-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500kg
- Release date
- 2018-08-19