ChemicalBook > CAS DataBase List > 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine

5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine

Product Name
5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
CAS No.
6981-18-6
Chemical Name
5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
Synonyms
OMP;NSC3272;Omeprin;NSC 3272;NSC-3272;NSC-95072;Ro 5-9754;ORMETOPRIN;ORMETOPRIM;ORMETHOPRIM
CBNumber
CB6333201
Molecular Formula
C14H18N4O2
Formula Weight
274.32
MOL File
6981-18-6.mol
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5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Property

Melting point:
231.0 to 235.0 °C
Boiling point:
521.5±60.0 °C(Predicted)
Density 
1.223±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
7.11±0.10(Predicted)
color 
Off-White
Water Solubility 
Water: Insoluble
λmax
287nm(CHCl3)(lit.)
Stability:
Hygroscopic
CAS DataBase Reference
6981-18-6(CAS DataBase Reference)
EPA Substance Registry System
Ormetoprim (6981-18-6)
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Safety

Safety Statements 
24/25
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
O0424
Product name
Ormetoprim
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$162
Updated
2021/12/16
TCI Chemical
Product number
O0424
Product name
Ormetoprim
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$562
Updated
2021/12/16
TRC
Product number
O686800
Product name
Ormetoprim
Packaging
1g
Price
$130
Updated
2021/12/16
Usbiological
Product number
O7049
Product name
Ormetoprim
Packaging
500ul
Price
$280
Updated
2021/12/16
Usbiological
Product number
227106
Product name
Ormetoprim
Packaging
500ul
Price
$360
Updated
2021/12/16
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5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Chemical Properties,Usage,Production

Uses

It is a potent and selective inhibitor of bacterial dihydrofolate reductase, the enzyme responsible for the NADPH-dependent reduction of 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate. Antibacterial.This compound is a contaminant of emerging concern (CECs).

Definition

ChEBI: 5-[(4,5-dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine is a dimethoxybenzene.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 14, p. 462, 1971 DOI: 10.1021/jm00287a029

5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Suppliers

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
Country
China
ProdList
96815
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Chembest Research Laboratories Limited
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+86-21-20908456
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021-58180499
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sales@BioChemBest.com
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China
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
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China
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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sales@jingyan-chemical.com
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China
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Chemsky (shanghai) International Co.,Ltd
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021-50135380
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shchemsky@sina.com
Country
China
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XiaoGan ShenYuan ChemPharm co,ltd
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15527768850
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1791901229@qq.com
Country
China
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8843
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Hangzhou Yuhao Chemical Technology Co., Ltd
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0571-82693216
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+86-571-82880190
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info@yuhaochemical.com
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China
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Heterochem
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027-88041443 13072715837
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027-51829379
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sales@hetero-chem.com
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China
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Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
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+86 21 50676805
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China
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Nanjing Norris-Pharm Technology Co., Ltd
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13901585132
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+86-25-52131256
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799750417@qq.com
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China
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View Lastest Price from 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ormetoprim 6981-18-6
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kgs
Release date
2021-10-15
Career Henan Chemical Co
Product
Ormetoprim 6981-18-6
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-02-04

6981-18-6, 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidineRelated Search:


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