ChemicalBook > CAS DataBase List > 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine

5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine

Product Name
5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
CAS No.
6981-18-6
Chemical Name
5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
Synonyms
OMP;NSC3272;NSC 3272;NSC-3272;NSC-95072;Ro 5-9754;ORMETOPRIN;ORMETOPRIM;ORMETHOPRIM;Ormetoprim>
CBNumber
CB6333201
Molecular Formula
C14H18N4O2
Formula Weight
274.32
MOL File
6981-18-6.mol
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5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Property

Melting point:
231.0 to 235.0 °C
Boiling point:
521.5±60.0 °C(Predicted)
Density 
1.223±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
7.11±0.10(Predicted)
color 
Off-White
Water Solubility 
Water: Insoluble
λmax
287nm(CHCl3)(lit.)
Stability:
Hygroscopic
CAS DataBase Reference
6981-18-6(CAS DataBase Reference)
EPA Substance Registry System
Ormetoprim (6981-18-6)
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Safety

Safety Statements 
24/25
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
O0424
Product name
Ormetoprim
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$162
Updated
2021/12/16
TCI Chemical
Product number
O0424
Product name
Ormetoprim
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$562
Updated
2021/12/16
TRC
Product number
O686800
Product name
Ormetoprim
Packaging
1g
Price
$130
Updated
2021/12/16
Usbiological
Product number
O7049
Product name
Ormetoprim
Packaging
500ul
Price
$280
Updated
2021/12/16
Usbiological
Product number
227106
Product name
Ormetoprim
Packaging
500ul
Price
$360
Updated
2021/12/16
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5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Chemical Properties,Usage,Production

Uses

It is a potent and selective inhibitor of bacterial dihydrofolate reductase, the enzyme responsible for the NADPH-dependent reduction of 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate. Antibacterial.This compound is a contaminant of emerging concern (CECs).

Definition

ChEBI: 5-[(4,5-dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine is a dimethoxybenzene.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 14, p. 462, 1971 DOI: 10.1021/jm00287a029

5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine Suppliers

Americas 1 Canada 1 China 113 Czech Republic 1 Germany 3 India 5 Japan 1 United Kingdom 7 United States 23 Global 155
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23662
Advantage
75
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View Lastest Price from 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ormetoprim 6981-18-6
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kgs
Release date
2021-10-15
Shaanxi Dideu Medichem Co. Ltd
Product
5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine 6981-18-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-05-07
Dideu Industries Group Limited
Product
5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine 6981-18-6
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-23

6981-18-6, 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidineRelated Search:

DIBENZYL SULFOXIDE 2-Methylindole Benzylacetone Tetramethylammonium chloride N,N-Dimethylformamide Pyrimidine 2-Pyrimidinamine, 5-methyl- (9CI) Diaveridine 5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4- diamine 5-ETHYL-2-PYRIMIDINAMINE 2,4-Diamino-5-(4-methoxybenzyl)pyrimidine 2,4-Diamino-5-(3-methoxybenzyl)pyrimidine 5-Benzyl-2,4-diaminopyrimidine 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine

  • ORMETHOPRIM
  • ORMETOPRIM
  • ORMETOPRIN
  • OMP
  • 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
  • L-Ascorbic Phosphate Magnesium
  • 2,4-DiaMino-5-92-Methyl-4,5- diMethoxybenzyl)pyriMidine
  • DiaMino-5-(6-Methylveratryl)pyriMidine
  • 2,4-Diamino-5-(6-methylveratryl)pyrimidine
  • 5-(4,5-Dimethoxy-2-methylbenzyl)pyrimidine-2,4-diamine
  • NSC-95072
  • Ro 5-9754
  • 5-[(4,5-Dimethoxy-2-methyl)phenylmethyl]-2,4-pyrimidine
  • 5-[(4,5-dimethoxy-2-methylphenyl)methyl]pyrimidine-2,4-diamine
  • Ormetoprim Standard
  • Ormetoprim&gt
  • 2,4-Pyrimidinediamine, 5-[(4,5-dimethoxy-2-methylphenyl)methyl]-
  • 2,4-Diamino-5-(4,5-dimethoxy-2-methylbenzyl)pyrimidine
  • 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine USP/EP/BP
  • 6981-18-6 5-(4,5-dimethoxy-2-methylbenzyl)-2,4-diaminopyrimidine
  • N'-Diphenylguanidine
  • NSC 3272
  • NSC3272
  • NSC-3272
  • 6981-18-6
  • Active Pharmaceutical Ingredients
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals