Epitheaflagallin 3-O-gallate

Epitheaflagallin 3-O-gallate Property

Boiling point:

1073.4±65.0 °C(Predicted)

Density 

1.95±0.1 g/cm3(Predicted)

pka

6.59±0.20(Predicted)

Hazard and Precautionary Statements (GHS)

Epitheaflagallin 3-O-gallate Chemical Properties,Usage,Production

Uses

Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. Epitheaflagallin 3-O-gallate exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts[1].

Definition

ChEBI: 5,7-Dihydroxy-2-{2,3,4,5-tetrahydroxy-6-oxo-6H-benzo[7]annulen-8-yl}-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate is a gallate ester.

Biological Activity

Epitheaflagallin 3-O-gallate is a minor polyphenol in black tea. It exhibits versatile physiological functions in vivo and in vitro, including antioxidative activity, pancreatic lipase inhibition, Streptococcus sorbinusglycosyltransferase inhibition, and an inhibiting effect on the activity of matrix metalloprotease-1 and -3 and their synthesis by human gingival fibroblasts.

References

[1] Itoh N, et al. Functional Characterization of Epitheaflagallin 3-O-Gallate Generated in Laccase-Treated GreenTea Extracts in the Presence of Gallic Acid. J Agric Food Chem. 2017 Dec 6;65(48):10473-10481. DOI:10.1021/acs.jafc.7b04208