2,2',4,4'-Tetrahydroxybenzophenone

ChemicalBook > CAS DataBase List > 2,2',4,4'-Tetrahydroxybenzophenone

2,2',4,4'-Tetrahydroxybenzophenone

Application Potential Exposure & Risk

Product Name: 2,2',4,4'-Tetrahydroxybenzophenone
CAS No.: 131-55-5
Chemical Name: 2,2',4,4'-Tetrahydroxybenzophenone
Synonyms: BENZOPHENONE-2;TETRAHYDROXYBENZOPHENONE;UV Absorber Benzophenone-2;70A-196;uvinuld-50;Uvinul D-50;Uvinol D-50;Seesorb 106;Sumisorb 150;Sinosorb? BP-2
CBNumber: CB6344256
Molecular Formula: C13H10O5
Formula Weight: 246.22
MOL File: 131-55-5.mol

Less

2,2',4,4'-Tetrahydroxybenzophenone Property

Melting point:: 198-200 °C(lit.)
Boiling point:: 349.21°C (rough estimate)
Density: 1.216
refractive index: 1.4825 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly, Sonicated), Methanol (Slightly)
form: Solid
pka: 6.98±0.35(Predicted)
color: Needles from H2O
Water Solubility: Slightly soluble in water.
BRN: 1914746
Stability:: Hygroscopic
InChIKey: WXNRYSGJLQFHBR-UHFFFAOYSA-N
LogP: 3.091 (est)
CAS DataBase Reference: 131-55-5(CAS DataBase Reference)
NIST Chemistry Reference: 2,2',4,4'-Tetrahydroxybenzophenone(131-55-5)
EPA Substance Registry System: 2,2',4,4'-Tetrahydroxybenzophenone (131-55-5)

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: DJ1892000
TSCA: Yes
HS Code: 29145090
Hazardous Substances Data: 131-55-5(Hazardous Substances Data)
Toxicity: LD50 oral in rat: 1220mg/kg

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T16403
Product name: 2,2′,4,4′-Tetrahydroxybenzophenone
Purity: 97%
Packaging: 25g
Price: $62.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: T16403
Product name: 2,2′,4,4′-Tetrahydroxybenzophenone
Purity: 97%
Packaging: 100g
Price: $135
Updated: 2024/03/01

TCI Chemical

Product number: T0118
Product name: 2,2',4,4'-Tetrahydroxybenzophenone
Purity: >98.0%(HPLC)
Packaging: 25g
Price: $39
Updated: 2024/03/01

Alfa Aesar

Product number: A10237
Product name: 2,2',4,4'-Tetrahydroxybenzophenone, 98+%
Packaging: 25g
Price: $39.65
Updated: 2024/03/01

Alfa Aesar

Product number: A10237
Product name: 2,2',4,4'-Tetrahydroxybenzophenone, 98+%
Packaging: 100g
Price: $108.65
Updated: 2024/03/01

Less

2,2',4,4'-Tetrahydroxybenzophenone Chemical Properties,Usage,Production

Application

2,2',4,4'-Tetrahydroxybenzophenone (BZP-2) is water-soluble and light-yellow powder (figure 1). BZP-2 is widely used in perfumes to prevent their degradation due to light. BZP-2 is a UV-absorber that helps protect against product degradation because of UV-light exposure and it is widely used in sunscreens and in cosmetics (figure 2), such as: anti-aging” creams and hair sprays and shampoos, paints and plastics. It can also mask odor associated with a formulation’s composition. In addition, the hypolipemiant drug fenofibrate is also a substituted benzophenone.

Potential Exposure & Risk

Although 2,2',4,4'-Tetrahydroxybenzophenone is used as a UV-blocker in cosmetics, plastics and automotive car products, its safety issue still should be noted. Such as workers that use BZP-2 may breathe in dust or have direct skin contact and the general population may be exposed by dermal contact with products containing this compound.
Skin allergic reaction has been reported in some people using sunscreens or cosmetics containing this compound. 2,2',4,4'-Tetrahydroxybenzophenone(BZP-2) is a member of a group of chemicals known as endocrine disruptors, which may alter the function and/or development of the reproductive system. Limited evidence indicates that exposure to benzophenone UV-absorbing chemicals, including BZP-2, is associated with an altered ratio of males to females at birth (increased females).

Chemical Properties

yellow to brown crystalline powder

Uses

2,2′,4,4′-Tetrahydroxybenzophenone are benzophenone-type UV filters with known or suspected endocrine disrupting properties detected in surface waters, sunscreens, personal care products, clothing and food packaging. It is used to protect the skin and materials from the adverse effects of UV-radiation.

Uses

2,2',4,4'-Tetrahydroxybenzophenone is used as the raw material of ultraviolet absorbers in cosmetics, plastics, resins and rubber. It is used as pharmaceutical intermediates and light-sensitive materials. It is also used as pharmaceutical adjuvant.

Uses

2,2',4,4'-Tetrahydroxybenzophenone is a uV-absorber that helps protect against product degradation because of uV-light exposure. It can also mask odor associated with a formulation’s composition.

Preparation

Obtained (small amount) by melting a fluorescin chloride/sodium hydroxide mixture in the presence of a very few water at 230–240° for 2–3 h.

Contact allergens

BZP-2 is widely used in perfumes to prevent their degradation due to light. It can cause allergic contact dermatitis.

Safety Profile

Moderately toxic by ingestion. Aneye irritant. Mutation data reported. When heated todecomposition it emits toxic fumes of NOx.

Synthesis

2 mol of resorcinol dimethyl ether is added dropwise to a mixture of 1 mol of phosgene and 1 mol of aluminum chloride, and the mixture is heated to 65-80° C at a temperature of 30-40° C in the presence of a chlorinated hydrocarbon selected from aliphatic and aromatic chlorides, such as ethylene dichloride. It is then cooled to 40° C, 2 to 3 mol of aluminum chloride are added, the mixture is heated to 60-70° C, dilute hydrochloric acid is treated with aqueous sodium hydroxide solution, and 2,2',4,4'-Tetrahydroxybenzophenone is isolated by filtration.

2,2',4,4'-Tetrahydroxybenzophenone Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2,2',4,4'-Tetrahydroxybenzophenone Suppliers

Belgium 5 Canada 1 China 399 Europe 3 France 1 Germany 11 India 12 Japan 7 Slovakia 1 South Korea 3 Switzerland 3 The Netherlands 3 Ukraine 1 United Kingdom 23 United States 48 USA 1 Global 522

Wuhan Qiaofeng Chemical Technology Co., Ltd.

Tel: 18271818137
Email: 2814999308@qq.com
Country: China
ProdList: 298
Advantage: 58

Qingdao Truelight functional Materials Technology Co., Ltd.

Tel: 0532-81159002 13573844393
Fax: 0532-81159002
Email: info@truelightchem.com
Country: China
ProdList: 202
Advantage: 58

Huangshi Jingsheng Biotechnology Co., Ltd.

Tel: 17771199833; 17771199833
Email: 351013952@qq.com
Country: China
ProdList: 2593
Advantage: 58

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9958
Advantage: 58

Tianjin Zhongxin Chemtech Co., Ltd.

Tel: 022-66880623
Fax: 86(0)22-66880086
Email: sales@tjzxchem.com
Country: China
ProdList: 613
Advantage: 60

Wuhan EnTai Technology Development Co,.Ltd

Tel: 86-27-82330560
Fax: 86-27-82330547
Email: 2536851935@qq.com
Country: China
ProdList: 347
Advantage: 69

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Changzhou Sunchem Pharmaceutical Chemical Material Co.,Ltd.

Tel: 0519-85195575 15861192208
Fax: 85195585
Email: 850305@sunkechem.com
Country: China
ProdList: 75
Advantage: 69

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 2963
Advantage: 65

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12390
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11655
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19172
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8843
Advantage: 52

Chembridge International Corp.(Taipei/Dongguan/Nanjing)

Tel: 025-84712192
Fax: 025-84712052
Email: china@chembridge.net
Country: China
ProdList: 192
Advantage: 62

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9815
Advantage: 79

Springchem New Material Technology Co.,Limited

Tel: +86-021-62885108 +8613917661608
Email: info@spring-chem.com
Country: China
ProdList: 2068
Advantage: 57

ZhengZhou HuaWen Chemical Co.Ltd

Tel: 0370-2785118 17550508557
Fax: QQ：3470079902
Email: 675141927@qq.com
Country: China
ProdList: 3203
Advantage: 55

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2872
Advantage: 58

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Fax: +86-25-52131256
Email: 799750417@qq.com
Country: China
ProdList: 8878
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Arbor Chemical Co., Ltd.

Tel: 021-60451683 15021268886
Fax: +86-21-60451682
Email: sales@arborchemical.com
Country: China
ProdList: 853
Advantage: 55

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3930
Advantage: 58

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

TianJin Alta Scientific Co., Ltd.

Tel: 022-65378550-8551
Fax: +86-022-2532-9655
Email: contact@altascientific.com
Country: China
ProdList: 2773
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Liyang Ruipu New Materials Co., Ltd.

Tel: +86-0519-82038123,18951201333
Fax: +86-519-87015112
Country: China
ProdList: 130
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2930
Advantage: 58

Zhengzhou HongSheng Pharmaceutical Co., Ltd.

Tel: 0371-13526885213 15637198702
Fax: 0371-63709726
Email: xpkchem@163.com
Country: China
ProdList: 3990
Advantage: 58

Deltachem (Qingdao) Co., Ltd

Tel: 18766299236
Fax: 0532-68856119
Email: summerzhai@deltachem.net
Country: China
ProdList: 163
Advantage: 58

Changzhou Sunchem Pharmaceutical Chemical Material Co.,Ltd.

Tel: 0519-85269522 13660798926
Fax: 013660798926
Email: sunlight68@126.com
Country: China
ProdList: 99
Advantage: 60

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Changzhou josenchem Pharmaceutical Chemical Material Co.,Ltd.

Tel: 519-519-85286950 13338194135
Fax: 0519-85286950
Email: info@josenchem.com
Country: China
ProdList: 75
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9648
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5875
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 7295
Advantage: 60

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10276
Advantage: 55

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.

Tel: 021-69106960 13701823733
Fax: 021-69106780
Email: 13701823733@163.com
Country: China
ProdList: 4767
Advantage: 60

Less

View Lastest Price from 2,2',4,4'-Tetrahydroxybenzophenone manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Benzophenone-2 131-55-5
Price: US $99.00-35.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-14

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2,2',4,4'-Tetrahydroxybenzophenone 131-55-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%min
Supply Ability: 500kg/month
Release date: 2021-06-01

Watson Biotechnology Co.,Ltd

Product: Benzophenone-2(BP-2) 131-55-5
Price: US $200.00-130.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20MT
Release date: 2024-07-27

131-55-5, 2,2',4,4'-TetrahydroxybenzophenoneRelated Search:

2,3,4-Trihydroxybenzoic acid Disodium 2,2'-dihydroxy-4,4'-dimethoxy-5,5'-disulfobenzophenone 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone 3,4-Dihydroxybenzophenone 2,4-Dihydroxybenzophenone Benzophenone Benzophenone imine 4-Hydroxybenzophenone 4,4'-Dihydroxybenzophenone UV Absorber 326 Octabenzone 2,2'-Thiobis(4-tert-octylphenolato)-n-butylamine nickel(II) Poly[N,N'-bis(2,2,6,6-tetramethyl-4-piperidinyl)-1,6-hexanediamine-co-2,4-dichloro-6-morpholino-1,3,5-triazine] UV Absorber 400 Tinuvin-1130 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid N-(2-Ethoxyphenyl)-N'-(4-ethylphenyl)-ethlyene diamide 2-Phenylbenzimidazole-5-sulfonic acid

2,2,4,4-Tetrahydroxybenzophenol

2,2’,4,4’-tetrahydroxy-benzophenon

2,2’,4,4’-tetrehydroxybenzophenone

2,2,4,4 TETRAHYDROXY BENZOPHENONE

2,4,2',4'-Tetrahydroxybenzophenone

2,4,2’,4’-tetrahydroxybenzophenone

Benzophenone, 2,2',4,4'-tetrahydroxy-

bis(2,4-dihydroxyphenyl)-methanon

Methanone, bis(2,4-dihydroxyphenyl)-

Uvinol D-50

Uvinul D-50

uvinuld-50

UV Absorber BP2

2,2',4,4'-Tetrahydroxybenzophenone (UV 246)

Benzophenone-2 (2,2'4,4'-Terahydroxy Benzophenone)

Benzophenone, 2,2'

2,2',4,4'-tetrahyroxybenzophenone

2,2',4,4'-TETRAHYDROXYBENZOPHENONE

DI(2,4-DIHYDROXYPHENYL)METHANONE

BENZOPHENONE-2

BENZOPHENONE-2-(2,2',4,4'-TETRAHYDROXYBENZOPHENONE)

BIS-(2,4-DIHYDROXY-PHENYL)-METHANONE

2,2',4,4'-Tetrahydroxybenzophenone(bp-2)

TIMTEC-BB SBB003178

2,2',4,4'-Tetrahydroxybenzophe

2.2''-4.4''-TETRAHYD[CL]ROXYBENZOPHENONE

2,2'',4,4''-TETRAHYDROXYBENZOPHENONE 98+%

2,2',4,4'-tetrahydroxy Benzophenone(Benzophenone-2)

Seesorb 106

Sumisorb 150

70A-196

TETRAHYDROXYBENZOPHENONE

2,2',4,4'-Tetrahydroxybenzophenone,97%

4-[(2,4-dihydroxyphenyl)carbonyl]benzene-1,3-diol

2,2',4,4'-Tetrahydroxybenzophenone&gt

UV Absorber Benzophenone-2

2,2’,4,4’-Tetrahydroxybenzophenone Solution in Acetonitrile, 100μg/mL

2,2',4,4'-Tetrahydroxybenzophenone ISO 9001：2015 REACH

UV ABSORBER TRUELICHT BP-2

2,2',4,4'-tetrahydroxy Benzophenone,Benzophenone-2(BP-2)

High purity CAS 131-55-5 2,2',4,4'-Tetrahydroxybenzophenone in stock

2,2',4,4'-Tetrahydroxybenzop

Sinosorb? BP-2

Phloroglucinol Impurity 88

2,2',4,4'-Tetrahydroxybenzophenone

2,2',4,4'-Tetrehydroxybenzophenone

2,2',4,4'-Tetrahydroxybenzophenone(BP-2)

Benzophenone-2(BP-2)

Zolmitriptan Impurity 1-d6

2,2',4,4'-Tetrahydroxybenzophenone in methanol

2,2',4,4'-Tetrehydroxybenzophenone (BP-2)

2,2′,4,4'-Tetrahydroxybenzophenone

131-55-5

C13H10O5

HO2C6H32CO

Ketones

Organic Building Blocks

Benzophenones (for High-Performance Polymer Research)