3-Hydroxy-N-methyl-3-phenyl-propylamine

Product Name: 3-Hydroxy-N-methyl-3-phenyl-propylamine
CAS No.: 42142-52-9
Chemical Name: 3-Hydroxy-N-methyl-3-phenyl-propylamine
Synonyms: 3-(METHYLAMINO)-1-PHENYLPROPAN-1-OL;3-METHYLAMINO-1-PHENYLPROPANOL;N-METHYL-3-PHENYL-3-HYDROXYPROPYLAMINE;α-[2-(MethyL;Compound PDK0217;Atomoxetine EP Imp H;Atomoxetine USP RC A;Fluoxetine Impurity 1;Fluoxetine EP IMpurity A;Fluoxertine EP impurity A
CBNumber: CB6345561
Molecular Formula: C10H15NO
Formula Weight: 165.24
MOL File: 42142-52-9.mol

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3-Hydroxy-N-methyl-3-phenyl-propylamine Property

Melting point:: 64 °C
Boiling point:: 170 °C / 31mmHg
Density: 1.017±0.06 g/cm3(Predicted)
vapor pressure: 0.037Pa at 25℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMSO (Soluble), Methanol (Slightly)
pka: 14.24±0.20(Predicted)
form: Solid
color: Off-White to Pale Yellow
InChI: InChI=1S/C10H15NO/c1-11-8-7-10(12)9-5-3-2-4-6-9/h2-6,10-12H,7-8H2,1H3
InChIKey: XXSDCGNHLFVSET-UHFFFAOYSA-N
SMILES: C(C1C=CC=CC=1)(O)CCNC
LogP: 0.98
CAS DataBase Reference: 42142-52-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36/37
WGK Germany: 3
HS Code: 2922199695

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0002201
Product name: Fluoxetine impurity A
Purity: CRS, European Pharmacopoeia (EP) Reference Standard
Packaging: Y0002201
Price: $156
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR2840
Product name: Atomoxetine Related Compound A
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 25MG
Price: $573
Updated: 2024/03/01

Sigma-Aldrich

Product number: 463477
Product name: α-[2-(Methylamino)ethyl]benzyl alcohol
Purity: 97%
Packaging: 1g
Price: $33
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1044470
Product name: Atomoxetine Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 10mg
Price: $1210
Updated: 2024/03/01

TCI Chemical

Product number: M1960
Product name: alpha-[2-(Methylamino)ethyl]benzyl Alcohol
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $35
Updated: 2024/03/01

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3-Hydroxy-N-methyl-3-phenyl-propylamine Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

α-[2-(Methylamino)ethyl]benzyl Alcohol (Fluoxetine EP Impurity A(Atomoxetine Related Compound A)) is an aromatic amino alcohol used as an initiator in radical addition reactions with tetrahalomethanes.This compound is found as an impurity in fluoxetine (F597100).

Uses

3-Hydroxy-N-methyl-3-phenyl-propylamine is an aromatic amino alcohol used as an initiator in radical addition reactions with tetrahalomethanes.

Synthesis

3-Hydroxy-N-methyl-3-phenyl-propylamine is one of important intermediate of preparation fluoxetine Hydrochloride. Up to now, the method for preparing N-methyl-3-phenyl-3-hydroxy-propylamine is mainly divided into three kinds; the first kind of be replace (halogen with 3-, dialkylamine, amido or ethoxycarbonyl) Propiophenone be starting raw material, earlier after reduction, the 1-phenylpropyl alcohol that 3-is replaced is converted into 3-Hydroxy-N-methyl-3-phenyl-propylamine again; Second kind and being: the different azoles alkane of 2-methyl-5-phenyl is carried out reductive ring open makes target compound; The third be: with getting the 1-phenylpropyl alcohol that 3-replaces behind epoxy styrene and the derivative reductive ring open thereof, be translated into target compound earlier.

3-Hydroxy-N-methyl-3-phenyl-propylamine Preparation Products And Raw materials

Raw materials

Preparation Products

Fluoxetine

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3-Hydroxy-N-methyl-3-phenyl-propylamine Suppliers

Americas 1 Belgium 2 Canada 3 China 316 Europe 2 Germany 5 India 33 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 11 United States 32 Global 412

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View Lastest Price from 3-Hydroxy-N-methyl-3-phenyl-propylamine manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: 3-Hydroxy-N-methyl-3-phenyl-propylamine 42142-52-9
Price: US $99.00-66.00/kg
Min. Order: 0.001kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-09

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 3-Hydroxy-N-methyl-3-phenyl-propylamine 42142-52-9
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%min
Supply Ability: 1000KG
Release date: 2021-07-22

Hebei Weibang Biotechnology Co., Ltd

Product: 3-Hydroxy-N-methyl-3-phenyl-propylamine 42142-52-9
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-29

42142-52-9, 3-Hydroxy-N-methyl-3-phenyl-propylamineRelated Search:

Benzyl benzoate Methyl acrylate Ethyl acetate Trimethylamine Benzyl bromide 1-Propanol Ethanol PHENYL VALERATE Ethylparaben Benzhydrylamine CHLOROPHOSPHONAZO III Benzyl alcohol Methylparaben trimethylamine oxide 1-Phenyl-1-propanol Kresoxim-methyl 3-Phenyl-1-propanol Flunixin meglumine

ALPHA-(2-METHYLAMINO)-ETHYLBENZENEMETHANOL

ALPHA-[2-(METHYLAMINO)ETHYL]BENZYL ALCOHOL

3-HYDROXY-N-METHYL-3-PHENYLPROPYLAMINE

3-METHYLAMINO-1-PHENYLPROPANOL

3-(METHYLAMINO)-1-PHENYLPROPAN-1-OL

3-METHYLAMINO-1-PHENYL-1-PROPANOL

N-METHYL-3-PHENYL-3-HYDROXYPROPYLAMINE

N-METHYL-3-HYDROXY-3-PHENYL PROPYLAMINE

(RS)-3-MethylaMino-1-Phenyl-Propan-1-ol

3-Hydroxy-N-Methyl-3-phenyl-propylaMin

alpha-[2-(MethylaMino)ethyl]benzyl alcohol 97%

Fluoxertine EP impurity A -C

(RS)-3-Methylamino-1-phenyl-1-propanol

Fluoxertine EP impurity A

3-(methylamino)-1-phenylpropan-1-ol Oxalate

Fluoxetine Impurity 1(EP-A)

Atomoxetine Impurity 8(Atomoxetine EP Impurity H)

Fluoxetine Hydrochloride Impurity Ⅰ：Fluoxetine EP Impurity A

Fluoxetine Impurity 1

Atomoxetine EP Imp H

A-[2-(Methylamino)Ethyl]Benzenemethanol

3-N-methyl-1-phenyl-propanol

BENZENEMETHANOL,A-[2-(METHYLAMINO)ETHYL]

3-methylamino-1-phenylpropano

α-[2-(Methylamino)ethyl]benzenemethanol

N-Methyl-3-Phenyl-3-Hydroxypropylamin

3-Methylamino-1-phenylpropane-1-ol

3-Hydroxy-N-methyl-3-phenyl-pr

α-[2-(methylamino)ethyl]benzyl alcohol

1-PHENYL-3-METHYLAMINO-1-PROPANOL

PHENYL METHYL AMINO PROPANOL

Propanol, 3-methylamino-1-phenyl

Benzenemethanol, α-[2-(methylamino)ethyl]-

Benzenemethanol, alpha-[2-(methylamino)ethyl]-

1-Phenyl-3-(methylamino)propane-1-ol

N-Methyl-3-hydroxy-3-phenyl-1-propanamine

N-Methyl-3-phenyl-3-hydroxypropylamine,97%

N-Methyl 3-phenyl-3-hydroxy-1-propanaMine

N-(3-Hydroxy-3-phenylpropyl)MethylaMine

N-Methyl-N-(3-hydroxy-3-phenylpropyl)aMine

3-Hydroxy-N-methyl-3-phenylpropylamine 3-(Methylamino)-1-phenylpropanol

Fluoxetine EP IMpurity A

Methyl({3-[3-(2-Methylphenoxy)phenyl]propyl})aMine

3-(Methylamino)-1-Phenyl-1-Ppropanol

α-[2-(Methylamino)ethyl]benzylAlcohol&gt

Fluoxetine EP Impurity A (Atomoxetine EP Impurity H)

Atomoxetine USP RC A

α-[2-(MethyL

3-Hydroxy-N-methyl-3-phenyl-propylamine USP/EP/BP

Fluoxetine intermediate，3-Hydroxy-N-methyl-3-phenyl- propylamine

Hydroxy-N-methyl-3-phenyl-propylamine

ALPHA-[2-(METHYLAMINO)ETHYL]BENZYL

Atomoxetine EP Impurity H/ Atomoxetine Related Compound A

3-Hydroxy-N-Methyl-3-Phenyl-Propylamine(42142-52-9)

Fluoxetine Hydrochloride Impurity Ⅰ：Fluoxetine EP Impurity A

α-[2-(Methylamino)ethyl]benzyl Alcohol

α-[2-(Methylamino)ethyl]benzenemethanol

(1RS)-3-(Methylamino)-1-phenylpropan-1-ol