NADP sodium salt

ChemicalBook > CAS DataBase List > NADP sodium salt

Product Name: NADP sodium salt
CAS No.: 1184-16-3
Chemical Name: NADP sodium salt
Synonyms: TPN;NADP SODIUM SALT;β-Nicotinamide Adenine Dinuclotide Phosphate;NADP Sodium;NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT;beta-Nicotinamide adenine dinucleotide phosphate hydrate;β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt Hydrate;β-NicotinaMide Adenine Dinucleotide Phosphate SodiuM Salt Hydrate (~90%);beta-NicotinaMide Adenine Dinucleotide Phosphate SodiuM Salt Hydrate, oxidized forM [for BiocheMical Research];TPN-NA
CBNumber: CB6355458
Molecular Formula: C21H29N7NaO17P3
Formula Weight: 767.41
MOL File: 1184-16-3.mol

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NADP sodium salt Property

Melting point:: 175-178 °C (dec.)(lit.)
storage temp.: -20°C
solubility: H₂O: 50 mg/mL
form: powder
color: off-white to yellow
PH: 2.0-4.0
Water Solubility: Soluble in water.
Merck: 14,6344
BRN: 4779954
InChI: InChI=1/C21H28N7O17P3.Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);/q;+1/p-1/t10-,11-,13-,14-,15-,16-,20-,21-;/s3
InChIKey: JNUMDLCHLVUHFS-QYZPTAICSA-M
SMILES: [C@H]1(O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@@H]2[C@@H](O)[C@@H](O)[C@H]([N+]3C=CC=C(C(=O)N)C=3)O2)[C@@H](O)[C@H]1OP(=O)(O)O)N1C=NC2C(N)=NC=NC1=2.[Na+] |&1:0,2,14,15,17,19,30,32,r|

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36-36/37/38
Safety Statements: 22-24/25-37/39-36-26
WGK Germany: 3
RTECS: UU3440000
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 481971-M
Product name: NADP, Monosodium Salt - CAS 1184-16-3 - Calbiochem
Purity: A coenzyme that is widely distributed in living matter. Participates in oxidation-reduction reactions. Spectra (pH 7.0): 250 nm/260 nm: 0.78-0.88; 280 nm/260 nm: 0.16-0.26.
Packaging: 481971-100MG
Price: $97.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 481971-M
Product name: NADP, Monosodium Salt - CAS 1184-16-3 - Calbiochem
Purity: A coenzyme that is widely distributed in living matter. Participates in oxidation-reduction reactions. Spectra (pH 7.0): 250 nm/260 nm: 0.78-0.88; 280 nm/260 nm: 0.16-0.26.
Packaging: 481971-500MG
Price: $288
Updated: 2024/03/01

Sigma-Aldrich

Product number: N8160
Product name: β-Nicotinamide adenine dinucleotide phosphate sodium salt
Purity: pkgof10?mg(pervial)
Packaging: 15vials
Price: $379
Updated: 2024/03/01

Sigma-Aldrich

Product number: 481971-M
Product name: NADP, Monosodium Salt - CAS 1184-16-3 - Calbiochem
Purity: A coenzyme that is widely distributed in living matter. Participates in oxidation-reduction reactions. Spectra (pH 7.0): 250 nm/260 nm: 0.78-0.88; 280 nm/260 nm: 0.16-0.26.
Packaging: 481971-1GM
Price: $434
Updated: 2024/03/01

Sigma-Aldrich

Product number: N8035
Product name: β-Nicotinamide adenine dinucleotide phosphate sodium salt
Purity: pkgof5?mg(pervial)
Packaging: 15vials
Price: $263
Updated: 2024/03/01

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NADP sodium salt Chemical Properties,Usage,Production

Description

The nicotinamide adenine dinucleotide phosphate oxidase（NADP）is a multicomponent system that transfers an electron to molecular oxygen by way of FAD and heme to form superoxide (O2?) .Cytochrome b558 is a membrane-bound heterodimer lodged in the wall of the secondary granules; the large glycosylated β subunit is gp91phox and the small nonglycosylated α subunit is p22phox.The cytoplasmic tail of gp91phox binds FAD, heme, and NADPH, which are required for electron transfer to oxygen (O2).Neutrophil stimulation leads to aggregation and phosphorylation of p47phox, p67phox, p40phox, and the small guanosine triphosphate (GTP)–binding proteins RAC1/RAC2, which dock with the cytochrome at the membrane through binding of p47phox and p22phox.

Description

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent ('hydrogen source').It is used by all forms of cellular life.

Chemical Properties

White to slightly yellowish powder

Uses

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions.
β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt Hydrate is a substrate NADP which plays a role in a variety of metabolic processes.

Uses

β-Nicotinamide adenine dinucleotide phosphate monosodium salt acts as an electron acceptor used by cells. It is also useful in vitro to study NADP. Furthermore, it is used in a wide range of enzyme catalyzed oxidation reduction reactions. The combination of NADP+/NADPH is employed in a variety of antioxidation mechanisms, which protect against reactive oxidation species accumulation.

Biosynthesis

In general, NADP+ is synthesized before NADPH is. Such a reaction usually starts with NAD+ from either the de-novo or the salvage pathway, with NAD+ kinase adding the extra phosphate group. ADP-ribosyl cyclase allows for synthesis from nicotinamide in the salvage pathway, and NADP+ phosphatase can convert NADPH back to NADH to maintain a balance.Some forms of the NAD+ kinase, notably the one in mitochondria, can also accept NADH to turn it directly into NADPH.[3][4] The prokaryotic pathway is less well understood, but with all the similar proteins the process should work in a similar way.

Biochem/physiol Actions

Electron acceptor

Mechanism of action

NADP sodium salt exerts its effect by competitively inhibiting nucleotide metabolism through the suppression of enzymes like nucleoside diphosphate kinase (NDPK) and adenosine kinase (ADK). Additionally, it serves as a substrate for enzymes like DNA polymerases and RNA polymerases, enabling the integration of NADP monosodium salt into nucleic acids during replication and transcription.

NADP sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from NADP sodium salt manufacturers

Henan Fengda Chemical Co., Ltd

Product: NADP sodium salt 1184-16-3
Price: US $8.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-29

Nantong Guangyuan Chemicl Co,Ltd

Product: β-NADP-sodium salt 1184-16-3
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2023-11-17

Hebei Duling International Trade Co. LTD

Product: BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT 1184-16-3
Price: US $100.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 100 tons
Release date: 2022-09-28

1184-16-3, NADP sodium salt Related Search:

Nadph tetrasodium salt NADP, Disodium Salt NAD+ Triphosphopyridine nucleotide Chlorotrimethylsilane Nicotinamide β-Nicotinamide Mononucleotide Adenosine-5'-diphosphate disodium salt Riboflavin Glutathione Superoxide dismutase Nicotinic acid NADH, disodium salt NADH Inhibitor Thionicotinamide adenine dinucleotide Adenosine triphosphate ATP disodium salt Adenosine-5'-diphosphate trilithium salt

β-NicotinaMide Adenine Dinucleotide Phosphate SodiuM Salt Hydrate (~90%)

beta-Nicotinamide adenine dinucleotide phosphate sodium salt beta-NADP sodium salt

NADP, MONOSODIUM SALT

NADP SODIUM SALT

CO II, NA

COENZYME II SODIUM SALT

BETA-NADP MONOSODIUM SALT

BETA-NADP-NA

BETA-NADP SODIUM SALT

BETA-NADP SODIUM SALT, HYDRATE

BETA-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE, MONOSODIUM SALT

BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT

BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT, HYDRATE

β-NADP-Na, β-NADP-sodium salt, Coenzyme II sodium salt, NADP, TPN-Na, TPN, Triphosphopyridine nucleotide sodium salt

Nicotinamide adenine dinucleotide sodium phosphate

β-Nicotinamide anenine dinucleotide,trihydrate

β-NADP-Na

beta-Nicotinamide adenine dinucleotide phosphate hydrate

Nicotinamide adenine dinucleotide phosphate-Na-salt

Adenosine 5-(trihydrogen diphosphate), 2-(dihydrogen phosphate), P?5-ester with 3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, inner salt, monosodium salt

beta-triphosphopyridine nucleotide sodium salt

BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE MONOSODIUM SALT (NADP SODIUM SALT)

Nicotinamide adenine dinucleotide phosphate >98% (oxidised form) monosodium salt

b-Nicotinamide adenine dinucleotide phosphate sodium salt

NADP, Monosodium Salt - CAS 1184-16-3 - Calbiochem

Monosodium nicotinamide adenine dinucleotide

β-Nicotinamide Adenine Dinuclotide Phosphate

Adenosine5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'5'-ester with3-(aminocarbonyl)-1-b-D-ribofuranosylpyridinium, inner salt, sodium salt (1:1)

beta-NicotinaMide Adenine Dinucleotide Phosphate SodiuM Salt&nbsp

Hydrate, oxidized forM [for BiocheMical Research]

Triphosphopyridine nucleotide, sodiuM salt, hydrate 500MG

Coenzyme II Sodium Salt beta-NADP Sodium Salt TPN Sodium Salt beta-Triphosphopyridine Nucleotide Sodium Salt

β-NicotinaMide Adenine Dinucleotide Phosphate SodiuM Salt Hydrate, oxidized forM [for BiocheMical Research]

^b-NicotinaMide adenine dinucleotide phosphate MonosodiuM salt

beta-Nicotinamide adenine dinucleotide phosphate sodium salt (NA

TPN MONOSODIUM SALT

TPN-NA

TPN SODIUM SALT

TPN

TRIPHOSPHOPYRIDINE NUCLEOTIDE SODIUM SALT

NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE SODIUM SALT

NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDISED FORM) MONOSODIUM SALT

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate,Triphosphopyridine nucleotide sodium salt hydrate

beta-NicotinaMide Adenine Dinucleotide Phosphate SodiuM Salt Hydrate, oxidized forM [for BiocheMical Research]

b-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate

Co II Na2

-NicotinaMide adenine dinucleotide,phosphate Na2

Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), 5'→5'-ester with 3-(aminocarbonyl)-1-β-d-ribofuranosylpyridinium hydroxide, inner salt, monosodium salt

beta-Nicotinamide adenine dinudeotide phosphate sodium salt (NADP)

Nicotinamide adenine din

Beta-nicotinamide adenine dinucleotide phosphate mono sodium salt (NADP Na)

Beta-Nicotinamideadenine dinucleotidephosphatesodium

β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate, oxidized form

β-Nicotinamide adenine dinucleotide phosphate monosodium salt

β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt 〔NADP

Beta-nicotinamide adenine dinucleotide phosphate(NADP+) Na

β-Nicotinamide Adenine Dinucleotide Phosphate monosodium

INADP-NA