Thionicotinamide adenine dinucleotide

Product Name: Thionicotinamide adenine dinucleotide
CAS No.: 4090-29-3
Chemical Name: Thionicotinamide adenine dinucleotide
Synonyms: S-NAD;THIO-NAD;Thio-Coenzyme;Thio-NAD >95%;Thio-NAD/S-NAD;S-NAD/ Thio-NAD;Thionicotinamide-NAD;THIONICOTINAMIDE-DPN;Nicotinamide Impurity 1;Thiooxidative coenzyme I
CBNumber: CB1208182
Molecular Formula: C21H27N7O13P2S
Formula Weight: 679.49
MOL File: 4090-29-3.mol

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Thionicotinamide adenine dinucleotide Property

storage temp.: -20°C
solubility: PBS (pH 7.2): 10 mg/ml
form: powder to crystal
color: Light orange to Yellow to Green
InChIKey: DQRRIGAXTAXHLR-NNYOXOHSSA-N
SMILES: O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP([O-])(=O)OC[C@@H]2[C@H]([C@@H](O)[C@H]([N+]3=CC=CC(C(=S)N)=C3)O2)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O |&1:1,2,3,15,16,17,19,32,r|
CAS DataBase Reference: 4090-29-3

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
WGK Germany: -
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T7375
Product name: Thionicotinamide adenine dinucleotide
Purity: ≥90%
Packaging: 25mg
Price: $193
Updated: 2025/07/31

Sigma-Aldrich

Product number: T7375
Product name: Thionicotinamide adenine dinucleotide
Purity: ≥90%
Packaging: 100mg
Price: $550
Updated: 2025/07/31

TCI Chemical

Product number: T2979
Product name: Thionicotinamide Adenine Dinucleotide oxidized form [for Biochemical Research]
Purity: >95.0%(HPLC)
Packaging: 100mg
Price: $310
Updated: 2025/07/31

TRC

Product number: T367763
Product name: Thionicotinamide adenine dinucleotide
Packaging: 500mg
Price: $90
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NT71492
Product name: Thionicotinamide adenine dinucleotide
Packaging: 1g
Price: $75
Updated: 2021/12/16

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Thionicotinamide adenine dinucleotide Chemical Properties,Usage,Production

Description

Thionicotinamide adenine dinucleotide is an analog of NAD. Use of Thio-NAD instead of NAD as a substrate for NAD(+)-consuming enzymes is more advantageous since the reduced form of Thio-NAD exhibits a substantial increase in absorbance at 405 nM, the most commonly available wavelength on microplate readers.

Chemical Properties

Light yellow powder

Uses

Thionicotinamide adenine dinucleotide has been used as a substrate analog in S-adenosyl-l-homocysteine (AdoHcy) hydrolases (SAHH) inhibition assay and in NAD+ glycohydrolase activity.

Application

Thionicotinamide adenine dinucleotide (thio-NAD) is a NAD derivative used in the determination of Carnitine by an enzymic cycling method with carnitine dehydrogenase.

Biochem/physiol Actions

Thionicotinamide adenine dinucleotide (sNAD) is an analog of coenzyme nicotinamide adenine dinucleotide (NAD) and NADH. sNAD is a potential inhibitor of NAD+ kinase. NAD+ kinase modulates NAD levels, contributing to cytotoxicity in cancer cells.

storage

Transport product sealed, dry, and protected from light at ambient temperature. Store product dry and protected from light. For long term storage keep below -20℃.

References

[1] SATOSHI WATABE. Ultrasensitive enzyme-linked immunosorbent assay (ELISA) of proteins by combination with the thio-NAD cycling method.[J]. Biophysics (Nagoya-shi, Japan), 2014, 10: 49-54. DOI: 10.2142/biophysics.10.49
[2] YUTA KYOSEI. Proposal of De Novo Antigen Test for COVID-19: Ultrasensitive Detection of Spike Proteins of SARS-CoV-2.[C]//10 8. 2020. DOI: 10.3390/diagnostics10080594
[3] WEN-HUNG WANG. A novel, rapid (within hours) culture-free diagnostic method for detecting live Mycobacterium tuberculosis with high sensitivity.[J]. EBioMedicine, 2020, 60: 103007. DOI: 10.1016/j.ebiom.2020.103007

Thionicotinamide adenine dinucleotide Preparation Products And Raw materials

Raw materials

Preparation Products

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Thionicotinamide adenine dinucleotide Suppliers

China 177 Germany 2 India 3 Japan 1 South Korea 1 Switzerland 1 United Kingdom 3 United States 10 USA 1 Global 199

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View Lastest Price from Thionicotinamide adenine dinucleotide manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.

Product: Thionicotinamide adenine dinucleotide 4090-29-3
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: 95%
Supply Ability: 20tons
Release date: 2025-05-27

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Thio-NAD 4090-29-3
Price: US $0.00/g
Min. Order: 1g
Purity: 99.0%
Supply Ability: 10kg/month
Release date: 2021-07-27

Shaanxi Dideu Medichem Co. Ltd

Product: Thionicotinamide adenine dinucleotide 4090-29-3
Price: US $30.00-20.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2024-08-01

4090-29-3, Thionicotinamide adenine dinucleotideRelated Search:

N-METHYLNICOTINAMIDE N-ETHYLNICOTINAMIDE Nicotinamide riboside chloride Ethionamide Nicotinamide Nicotinamide riboside Triphosphopyridine nucleotide Nadph tetrasodium salt NADP sodium salt NADH, disodium salt NADH Inhibitor Nicotinamide hypoxanthine dinucleotide phosphate reduced tetrasodium salt NADP, Disodium Salt NAD+ β-Nicotinamide Mononucleotide Nicotinamide-N-oxide 6-METHYLNICOTINAMIDE N,N'-DIPYRIDIN-3-YLUREA

THIONICOTINAMIDE ADENINE DINUCLEOTIDE

THIONICOTINAMIDE-DPN

THIO-NAD

adenosine 5'-(trihydrogen diphosphate), 5'->5'-ester with 3-(aminothioxomethyl)-1-beta-D-ribofuranosylpyridinium--ate

Thionicotinamide-NAD

beta-Thionicotinamide adenine dinucleotide, oxidised form 92+%

3-Thiocarbamoylpyridine adenine dinucleotide

3-Thionicotinamide adenine dinucleotide

Thino-Nicotinamide Adenine Dinuclotide

Adenosine5'-(trihydrogen diphosphate), P'5'-ester with 3-(aminothioxomethyl)-1-b-D-ribofuranosylpyridinium, inner salt

Thionicotinamide Adenine Dinucleotide(THIO-NAD)

ThionicotinaMide Adenine Dinucleotide oxidized forM [for BiocheMical Research]

5'-ester with 3-(aMinothioxoMethyl)-1-b-D-ribofuranosylpyridiniuM, inner salt

Adenosine5'-(trihydrogen diphosphate), P'&reg

Thionicotinamide-DPN oxidized form

β-ThionicotinaMide adenine dinucleotide, Oxidized forM

β-Thionicotinamide adenine dinucleotide, 90%, Oxidized form

Thio-Nicotinamide-Adenine Dinucleotide, Oxidized (Thio-NAD).

Thio-NAD/S-NAD

Thio-Nicotinamide Adenine Dinuclotide

Thio-NAD Thionicotinamide adenine dinucleotide

Thiooxidative coenzyme I

Thionicotinamide Adenine Dinucleotide (Thio-NAD) extrapure, 90%

Nicotinamide Impurity 1

Thio-Coenzyme

Thio-NAD >95%

S-NAD

S-NAD/ Thio-NAD

1-((2R,3R,4S,5R)-5-((((((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)oxidophosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-3-carbamothioylpyridin-1-ium

Thio oxidized coenzyme I/thio coenzyme/reduced nicotinamide hypoxanthine dinucleotide

Protirelin Impurity 3 (Protirelin EP Impurity C)

Oxidized thio coenzyme I

THIONICOTINAMIDE ADENINE DINUCLEOTIDE 98%with hydrate one

Thionicotinamide adenine dinucleotide【T7375】

beta-Thionicotinamide adenine dinucleotide, oxidised form

4090-29-3

C21H27N7O13P2S

C21H27N7O13SP2

BioChemical

Biochemicals and Reagents

Cofactors

Enzymes, Inhibitors, and Substrates

Oxidation-Reduction

nucleoside