Nicotinamide-N-oxide

Product Name: Nicotinamide-N-oxide
CAS No.: 1986-81-8
Chemical Name: Nicotinamide-N-oxide
Synonyms: AKOS 94294;N-oxyamide;Oxynicotinamide;1-OXY-NICOTINAMIDE;Nicotinamid-N-oxid;TIMTEC-BB SBB004187;NICOTINAMIDE N-OXIDE;NICOTINAMIDE 1-OXIDE;nicotinamide N1-oxide;NicotinamideN-Oxide>
CBNumber: CB7664988
Molecular Formula: C6H6N2O2
Formula Weight: 138.12
MOL File: 1986-81-8.mol

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Nicotinamide-N-oxide Property

Melting point:: 291-293 °C (dec.)(lit.)
Boiling point:: 253.51°C (rough estimate)
Density: 1.3471 (rough estimate)
refractive index: 1.5100 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form: Solid
pka: 14.38±0.50(Predicted)
color: White to Off-White
Sensitive: Hygroscopic
Major Application: pharmaceutical small molecule
InChI: 1S/C6H6N2O2/c7-6(9)5-2-1-3-8(10)4-5/h1-4H,(H2,7,9)
InChIKey: USSFUVKEHXDAPM-UHFFFAOYSA-N
SMILES: NC(=O)c1ccc[n+]([O-])c1
CAS DataBase Reference: 1986-81-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29339900
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: N0669
Product name: Nicotinamide N-Oxide
Purity: >98.0%(T)
Packaging: 5g
Price: $83
Updated: 2025/07/31

TCI Chemical

Product number: N0669
Product name: Nicotinamide N-Oxide
Purity: >98.0%(T)
Packaging: 25g
Price: $329
Updated: 2025/07/31

Cayman Chemical

Product number: 28441
Product name: Nicotinamide N-oxide
Packaging: 5g
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 28441
Product name: Nicotinamide N-oxide
Packaging: 10g
Price: $78
Updated: 2024/03/01

Cayman Chemical

Product number: 28441
Product name: Nicotinamide N-oxide
Packaging: 25g
Price: $151
Updated: 2024/03/01

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Nicotinamide-N-oxide Chemical Properties,Usage,Production

Description

Nicotinamide N-oxide is a metabolite of nicotinamide . It is formed via oxidation of nicotinamide by the cytochrome P450 (CYP) isoform CYP2E1. Nicotinamide N-oxide (30 mM) inhibits proliferation and induces reduction of nitroblue tetrazolium (NBT; ), indicating cell differentiation, in HL-60 promyelocytic leukemia cells. Urine levels of nicotinamide N-oxide are elevated in a mouse model of high-fat diet-induced obesity.

Chemical Properties

WHITE TO SLIGHTLY YELLOW FLUFFY CRYST. NEEDLES

Uses

A metabolite of Nicotinamide.

Definition

ChEBI: Nicotinamide N-oxide is a member of pyridines.

References

[1] ALEXANDER MICHAEL REAL P P Shangyu Hong. Nicotinamide N-oxidation by CYP2E1 in human liver microsomes.[J]. Drug Metabolism and Disposition, 2013, 41 3: 550-553. DOI: 10.1124/dmd.112.049734
[2] KEIKO IWATA. Induction of differentiation in human promyelocytic leukemia HL-60 cell line by niacin-related compounds.[J]. Bioscience, Biotechnology, and Biochemistry, 2003, 67 5: 1132-1135. DOI: 10.1271/bbb.67.1132
[3] JEE-YOUN JUNG. 1H NMR-based metabolite profiling of diet-induced obesity in a mouse mode.[J]. BMB Reports, 2012, 45 7: 419-424. DOI: 10.5483/bmbrep.2012.45.7.248

Nicotinamide-N-oxide Preparation Products And Raw materials

Raw materials

Nicotinamide Hydrogen peroxide Acetic acid

Preparation Products

Forchlorfenuron

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Nicotinamide-N-oxide Suppliers

Americas 1 Belgium 1 Canada 3 China 156 Europe 2 Germany 6 India 22 Ireland 1 Japan 4 South Korea 1 Switzerland 2 The Netherlands 1 United Kingdom 10 United States 33 Global 243

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
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Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Wuhan Chemwish Technology Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
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ProdList: 9976
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

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ProdList: 11598
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Nanjing Habo Medical Technology Co., Ltd.

Tel: 025-85760892 13376080562
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Adamas Reagent, Ltd.

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ProdList: 14101
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View Lastest Price from Nicotinamide-N-oxide manufacturers

Career Henan Chemical Co

Product: Nicotinamide-N-oxide 1986-81-8
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-21

1986-81-8, Nicotinamide-N-oxideRelated Search:

ETHYLENE OXIDE Nicotinamide NITRIC OXIDE Iron oxide Pyridinium chlorochromate Zinc oxide Magnesium oxide Propylene oxide THIONICOTINAMIDE (Diethoxymethyl)diphenylphosphine oxide Ethyl nicotinate Nicotinic acid NAD+ Nicotinamide riboside MYRISTYL NICOTINATE Nicotinic Acid Riboside Benzyl nicotinate β-Nicotinamide Mononucleotide

1-OXY-NICOTINAMIDE

3-(AMINOCARBONYL)PYRIDINIUM-1-OLATE

AKOS 94294

NICOTINAMIDE 1-OXIDE

NICOTINAMIDE N-OXIDE

TIMTEC-BB SBB004187

3-Pyridinecarboxamide, 1-oxide

3-Pyridinecarboxamide,1-oxide(9CI)

1-Oxidopyridin-1-ium-3-carboxamide

Nicotinamide-N-oxide ,98%

3-Carbamoylpyridine 1-oxide

3-Pyridinecarbamide 1-oxide

nicotinamide N1-oxide

Oxynicotinamide

Nicotinamide Impurity 5(Nicotinamide EP Impurity E)

N-oxo-3-pyridinecarboxamide

Nicotinamide EP Impurity E

Nicotinamid-N-oxid

NicotinamideN-Oxide&gt

Nicotinamide EP Impurity E (Nicotinamide N-Oxide)

Nicotinamide-N-oxide USP/EP/BP

pyridine-3-carboxamide 1-oxide (nicotinamide N-oxide)

Nicotinamide Impurity E

Nicotinamide nitrogen oxide

Nicotinamide N-oxide, 10 mM in DMSO

Nicotinamide Impurity 5

N-oxyamide

1986-81-8

NAD and Analogs

Nucleosides, Nucleotides, Oligonucleotides

BioChemical

Biochemicals and Reagents

Amines, Heterocycles, Metabolites & Impurities, Nicotine Derivatives, Nucleotides, Bases & Related Reagents

Amines

Bases & Related Reagents

Heterocycles

Metabolites & Impurities

Nicotine Derivatives

Nucleotides

AMIDE

Biochemicals and Reagents

NAD and Analogs

Nucleosides, Nucleotides, Oligonucleotides