N-METHYLNICOTINAMIDE

Product Name: N-METHYLNICOTINAMIDE
CAS No.: 114-33-0
Chemical Name: N-METHYLNICOTINAMIDE
Synonyms: Methylnicotinamide;N-METHYLNICOTINAMIDE;N'-METHYLNICOTINAMIDE;METHYLNICOTINAMIDE, N-;N-Methylnicotinamide>Nicotinamide Impurity 7;N-Methylnicotinamide,98%;Nicotinamide Impurity 121;Nicotinic Acid Methylamide;N-Methylnicotinamide
CBNumber: CB6151285
Molecular Formula: C7H8N2O
Formula Weight: 136.15
MOL File: 114-33-0.mol

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N-METHYLNICOTINAMIDE Property

Melting point:: 102-105 °C(lit.)
Boiling point:: 250.42°C (rough estimate)
Density: 1.1778 (rough estimate)
refractive index: 1.5769 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 13.97±0.46(Predicted)
color: White to Off-White
CAS DataBase Reference: 114-33-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2933.39.9200

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M0374
Product name: N-Methylnicotinamide
Purity: >98.0%(GC)(T)
Packaging: 10g
Price: $82
Updated: 2024/03/01

TCI Chemical

Product number: M0374
Product name: N-Methylnicotinamide
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $134
Updated: 2024/03/01

Cayman Chemical

Product number: 21850
Product name: N-Methylnicotinamide
Purity: ≥98%
Packaging: 5g
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 21850
Product name: N-Methylnicotinamide
Purity: ≥98%
Packaging: 10g
Price: $77
Updated: 2024/03/01

Cayman Chemical

Product number: 21850
Product name: N-Methylnicotinamide
Purity: ≥98%
Packaging: 25g
Price: $143
Updated: 2024/03/01

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N-METHYLNICOTINAMIDE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow-beige crystalline powder

Uses

N-Methylnicotinamide is a metabolite of Nicotinamide (N407750), which is a water-soluble vitamin B, incorporated within nicotinamide cofactors such as NADH and NADPH. N-Methylnicotinamide is commonly found in the human urine and is used as a biomarker to study diseases such as liver cirrhosis and type 2 diabetes.

Definition

ChEBI: A pyridinecarboxamide that is nicotinamide in which one of the amide hydrogens is substituted by a methyl group.

in vivo

N-Methylnicotinamide (3-30 mg/kg, i.v., 10 min before the induction of arterial thrombosis) decreases the arterial thrombus weight, collagen induced platelet aggregation and decreases PAI-1 antigen and activity in plasma without changing t-PA activity in 2K-1C hypertensive rats^[1].
N-Methylnicotinamide (30-300 mg/kg, mixed in the diet, daily for 31 days) significantly increases the liver weight, the content of NAD and total nicotinamide in liver and the content of NAD in blood in rats^[3].

Animal Model:	2K-1C hypertensive rats^[1]
Dosage:	3-30 mg/kg
Administration:	i.v., 10 min before the induction of arterial thrombosis
Result:	Resulted in a dose-dependent decrease of arterial thrombus weight, decreased PAI-1 antigen and activity in plasma in dose-dependent manner, whereas it did not change t-PA activity, decreased collagen induced platelet aggregation in dose-dependent manner.

Animal Model:	Weanling male rats^[3]
Dosage:	30-300 mg/kg
Administration:	mixed in the diet, daily for 31 days
Result:	Significantly increased the liver weight, statistically significantly the content of NAD and total nicotinamide in liver and the content of NAD in blood in rats.

IC 50

Microbial Metabolite; Human Endogenous Metabolite

N-METHYLNICOTINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHYLNICOTINAMIDE Suppliers

Americas 1 Belgium 1 China 105 Europe 4 Germany 2 India 5 Japan 3 Slovakia 1 South Korea 1 Switzerland 2 United Kingdom 4 United States 18 Global 147

Shanghai XinKai Chemical Technology Co., Ltd.

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Maya High Purity Chemicals

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View Lastest Price from N-METHYLNICOTINAMIDE manufacturers

Career Henan Chemical Co

Product: N-METHYLNICOTINAMIDE 114-33-0
Price: US $9.80/KG
Min. Order: 1g
Purity: ＞98%
Supply Ability: 20 tons
Release date: 2020-02-10

114-33-0, N-METHYLNICOTINAMIDERelated Search:

6-METHYLPYRIDINE-3-CARBOXAMIDE (6-METHYLNICOTINAMIDE) Nicotinamide NADP, Disodium Salt Thionicotinamide adenine dinucleotide Ethionamide Nicotinamide riboside chloride NADH, disodium salt Nicotinamide-N-oxide N,N'-DIPYRIDIN-3-YLUREA N-ETHYLNICOTINAMIDE 5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione nicopholine N-Nicotinoylglycine N-METHYLNICOTINAMIDE NICOTINANILIDE 3-Pyridinecarboxylic acid N-hydroxymethylamide N,N-DIETHYLNICOTINAMIDE 3,4-PYRIDINEDICARBOXIMIDE

N'-METHYLNICOTINAMIDE

N-METHYLNICOTINAMIDE

METHYLNICOTINAMIDE, N-

Methylnicotinamide

3-Pyridinecarboxamide, N-methyl-

N-Methyl-3-pyridinecarboxamide.

3-Pyridinecarboxamide,N-methyl-(9CI)

N-Methylnicotinamide, GC 98%

N-Methylpyridine-3-carboxamide

N-Methylnicotinamide,98%

<i>N</i>-Methylnicotinamide

N-Methylnicotinamide&gt

Nicotinic Acid Methylamide

Sorafenib tosylate Impurity 4

Nicotinamide Impurity 7

3-(Methylcarbamoyl)pyridine

3-(Methylcarbamoyl)pyridine , N-Methylnicotinamide

Nicotinamide Impurity 121

N-Methylnicotinamide, 10 mM in DMSO

114-33-0

AMIDE