2-Bromo-6-fluoroanisole

Product Name: 2-Bromo-6-fluoroanisole
CAS No.: 845829-94-9
Chemical Name: 2-Bromo-6-fluoroanisole
Synonyms: 2-BROMO-6-FLUOROANISOLE;1-Bromo-3-fluoro-2-methoxybenze;1-BROMO-3-FLUORO-2-METHOXY-BENZENE;Benzene, 1- bromo- 3- fluoro- 2- methoxy-;2-Bromo-6-fluoroanisole ISO 9001：2015 REACH
CBNumber: CB6371173
Molecular Formula: C7H6BrFO
Formula Weight: 205.02
MOL File: 845829-94-9.mol

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2-Bromo-6-fluoroanisole Property

Boiling point:: 208.6±20.0 °C(Predicted)
Density: 1.531±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: liquid
color: colorless
InChI: InChI=1S/C7H6BrFO/c1-10-7-5(8)3-2-4-6(7)9/h2-4H,1H3
InChIKey: RLSQPLJXDTXSCL-UHFFFAOYSA-N
SMILES: C1(Br)=CC=CC(F)=C1OC
CAS DataBase Reference: 845829-94-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2909309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 024819
Product name: 2-Bromo-6-fluoroanisole
Purity: 98%
Packaging: 5g
Price: $36
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50808
Product name: 2-Bromo-6-fluoroanisole
Packaging: 250mg
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50808
Product name: 2-Bromo-6-fluoroanisole
Packaging: 500mg
Price: $110
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0050260
Product name: 1-BROMO-3-FLUORO-2-METHOXYBENZENE
Purity: 95.00%
Packaging: 1G
Price: $123.9
Updated: 2021/12/16

Matrix Scientific

Product number: 024819
Product name: 2-Bromo-6-fluoroanisole
Purity: 98%
Packaging: 25g
Price: $154
Updated: 2021/12/16

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2-Bromo-6-fluoroanisole Chemical Properties,Usage,Production

Chemical Properties

Colorless to pale yellow liquid

Uses

2-Bromo-6-fluoroanisole is a reactant in the preparation of quinazolines as a c-jun N-terminal kinase (JNK) inhibitor with good brain penetration.

Synthesis

2040-89-3

74-88-4

845829-94-9

GENERAL METHOD: 2-bromo-6-fluorophenol (0.1 mol) was dissolved in DMF (100 mL) and K2CO3 (0.1 mol) and iodomethane (0.1 mol) were added sequentially. The reaction mixture was stirred at room temperature for 24 hours. After the reaction was completed, water (400 mL) was added to dilute and the mixture was extracted with hexane. The organic phase was separated, washed with water, dried over anhydrous sodium sulfate, filtered through a short column of silica gel and the filtrate was concentrated under reduced pressure to give 2-bromo-6-fluoroanisole.

References

[1] European Journal of Medicinal Chemistry, 2015, vol. 89, p. 524 - 539

2-Bromo-6-fluoroanisole Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromo-6-fluoroanisole Suppliers

Canada 1 China 138 Europe 1 India 1 United Kingdom 8 United States 19 Global 168

Shanghai Harvest Chemical Industrial Co., Ltd.

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View Lastest Price from 2-Bromo-6-fluoroanisole manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Bromo-6-fluoroanisole 845829-94-9
Price: US $0.00-0.00/KG
Min. Order: 10mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-17

Career Henan Chemical Co

Product: 2-Bromo-6-fluoroanisole 845829-94-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-11

845829-94-9, 2-Bromo-6-fluoroanisoleRelated Search:

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2-BROMO-6-FLUOROANISOLE

1-BROMO-3-FLUORO-2-METHOXY-BENZENE

Benzene, 1- bromo- 3- fluoro- 2- methoxy-

1-Bromo-3-fluoro-2-methoxybenze

2-Bromo-6-fluoroanisole ISO 9001：2015 REACH

845829-94-9

C07H06BrFO

Benzenes

Benzene series