2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide
- Product Name
- 2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide
- CAS No.
- 1099592-35-4
- Chemical Name
- 2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide
- Synonyms
- NASH;NSAH, 10 mM in DMSO;Naphthyl salicylic acyl hydrazone;(E)-2-Hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide;(E)-2-Hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide;DNA/RNA Synthesis,HCT116,MDA-231,Panc1,Inhibitor,NSAH,inhibit,S-phase;2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide;2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide;Benzoic acid, 2-hydroxy-, (2E)-2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
- CBNumber
- CB63715947
- Molecular Formula
- C18H14N2O3
- Formula Weight
- 306.32
- MOL File
- 1099592-35-4.mol
2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Property
- storage temp.
- Store at -20°C
- solubility
- DMSO : 62.5 mg/mL (204.03 mM; Need ultrasonic)
- form
- Solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-0063330
- Product name
- NSAH
- Purity
- 98.62%
- Packaging
- 5mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- CS-0063330
- Product name
- NSAH
- Purity
- 98.62%
- Packaging
- 10mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- CS-0063330
- Product name
- NSAH
- Purity
- 98.62%
- Packaging
- 25mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- CS-0063330
- Product name
- NSAH
- Purity
- 98.62%
- Packaging
- 50mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- CS-0063330
- Product name
- NSAH
- Purity
- 98.62%
- Packaging
- 100mg
- Price
- $720
- Updated
- 2021/12/16
2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Chemical Properties,Usage,Production
Biological Activity
NSAH is a cell penetrant, potent and selective nonnucleoside reversible inhibitor of large subunit (hRRM1) of hRR (human ribonucleotide reductase). NSAH binds to catalytic site of hRRM1. It inhibits hRR in cells. NSAH exhibit potent cytotoxicity toward cancer cells, while demonstrated very moderate toxicity against normal blood progenitor cells.
2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Preparation Products And Raw materials
Raw materials
Preparation Products
2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Suppliers
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