ISOTETRANDRINE

ChemicalBook > CAS DataBase List > ISOTETRANDRINE

Product Name: ISOTETRANDRINE
CAS No.: 477-57-6
Chemical Name: ISOTETRANDRINE
Synonyms: NSC 97338;isosinomenina;ISOTETRANDRINE;isosinomeninea;1-isotetrandrine;O-METHYLBERBAMINE;(r,s)-tetrandrine;1-Isotetrandrine(8CI);o,o’-dimethylobamegine;BERBAMINE METHYL ETHER
CBNumber: CB6376880
Molecular Formula: C38H42N2O6
Formula Weight: 622.76
MOL File: 477-57-6.mol

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ISOTETRANDRINE Property

Melting point:: 180-182℃
Boiling point:: 710.5±60.0 °C(Predicted)
Density: 1.172
RTECS: NX7285000
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Off-white solid.
pka: 7.70±0.20(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar

Product number: J67081
Product name: Isotetrandrine, 98%
Packaging: 1mg
Price: $120
Updated: 2023/06/20

TRC

Product number: I918015
Product name: Isotetrandrine
Packaging: 50mg
Price: $685
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0001324
Product name: ISOTETRANDRINE
Purity: 98.00%
Packaging: 25MG
Price: $1270.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0001324
Product name: ISOTETRANDRINE
Purity: 98.00%
Packaging: 1MG
Price: $187.95
Updated: 2021/12/16

Arctom

Product number: AS325629
Product name: Isotetrandrine
Packaging: 5mg
Price: $226
Updated: 2021/12/16

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ISOTETRANDRINE Chemical Properties,Usage,Production

Description

A bisbenzylisoquinoline alkaloid, shown to be identical with berbamine methyl ether, this base occurs in A therosperrna rnoschaturn, Berberis japonica and Stephania cephalantha. It is dextrorotatory with [α]¹⁷_D + 146° or[α]²⁰_D + 150.7° (c 0.85, CHC13). When recrystallized from MeOH it forms colourless crystals and furnishes a crystalline dimethiodide, m.p. 242°C. Four methoxyl groups and two methylimino groups are present.

Uses

Isotetrandrine is a biscoclaurine alkaloid inhibitor of G protein activation of PLA2.

target

IL Receptor | NF-kB | MAPK | Nrf2 | HO-1 | JNK

References

Kondo et al., J. Pharrn. Soc., Japan, 58,920 (1938)
Tomita, Fujita, Morai., ibid, 71,226,301 (1951)
Bick, Clezy, Crow., Austral. J. Chern., 9, III (1956)
Synthesis:
Inubushi et ai., Tetrahedron Lett., 3399 (1968)

ISOTETRANDRINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ISOTETRANDRINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Isotetrandrine 477-57-6
Price: US $30.00-20.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2024-08-06

Career Henan Chemical Co

Product: ISOTETRANDRINE 477-57-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons
Release date: 2020-03-12

477-57-6, ISOTETRANDRINERelated Search:

Demethyl tetrandrine N-Methyl-3-phenoxybenzylamine 2,3,4-Trimethoxybenzylamine (R)-(+)-Tetrahydropapaverine SALSOLIDINE (R)-1-(3,4-Dimethoxyphenyl)ethylamine 3-PHENOXYPHENETHYLAMINE N-METHYL-N-(2-PHENOXYBENZYL)AMINE 97+% (+/-)-Tetrahydropapaverine (S)-1-(3,4-Dimethoxyphenyl)ethylamine MAGNOLINE 2,2'-DIHYDROXYDIPHENYL ETHER BERBAMINE DL-LAUDANOSINE ISOTETRANDRINE CHEMBRDG-BB 5209105 3,4,5-TRIMETHOXYPHENETHYLAMINE, HYDROCHLORIDE Phenol, 4-(1-aminoethyl)-2-methoxy-, (R)- (9CI)

1-isotetrandrine

6,6’,7,12-tetramethoxy-2,2’-dimethyl-berbama

isosinomenina

isosinomeninea

o,o’-dimethylobamegine

o,o’-dimethylstepholine

O-METHYLBERBAMINE

BERBAMINE METHYL ETHER

ISOTETRANDRINE

(r,s)-tetrandrine

(4aS,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline

NSC 97338

16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2',3':17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aS,16aR)-

1-Isotetrandrine(8CI)

O,O'-Dimethylstepholine

477-57-6

C38H42N2O6

Alkaloids