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N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT

Product Name
N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT
CAS No.
81921-35-9
Chemical Name
N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT
Synonyms
6-Me-5'-AMP;N6-5′,-Me-AMP;N-Methyl-5'-adenylic acid disodium salt;N6-methyladenosine 5'-monophosphate*sodium;5'-?Adenylicacid,N-?methyl-?,disodiumsalt(9CI);N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT;N6-Methyladenosine 5'-monophosphate disodium salt;ML-210N6-Methyladenosine 5'-monophosphate (sodium salt);N6-Methyladenosine 5'-monophosphate sodium salt;N6-Methyladenosine 5'-Monophosphate sodiuM salt ~98% (HPLC)
CBNumber
CB6385033
Molecular Formula
C11H14N5Na2O7P
Formula Weight
405.21
MOL File
81921-35-9.mol
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N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT Property

storage temp. 
-20°C
solubility 
PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
color 
White to light brown
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M2780
Product name
N6-Methyladenosine 5′-monophosphate sodium salt
Purity
≥97% (HPLC)
Packaging
10mg
Price
$504
Updated
2025/07/31
Cayman Chemical
Product number
23382
Product name
N6-Methyladenosine 5'-monophosphate (sodium salt)
Purity
≥95%
Packaging
5mg
Price
$110
Updated
2024/03/01
Cayman Chemical
Product number
23382
Product name
N6-Methyladenosine 5'-monophosphate (sodium salt)
Purity
≥95%
Packaging
10mg
Price
$195
Updated
2024/03/01
Cayman Chemical
Product number
23382
Product name
N6-Methyladenosine 5'-monophosphate (sodium salt)
Purity
≥95%
Packaging
25mg
Price
$407
Updated
2024/03/01
TRC
Product number
M275898
Product name
N6-Methyladenosine 5′-monophosphate sodium salt
Packaging
5mg
Price
$140
Updated
2021/12/16
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N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT Chemical Properties,Usage,Production

Description

N6-Methyladenosine 5''-monophosphate is an activator of glycogen phosphorylase b (Ka = 22 μM). It is also a non-competitive inhibitor of rat adenylate kinase II (Ki = 4.2 mM). N6-Methyladenosine 5’-monophosphate (sodium salt) has been used for immunoprecipitation of N6-methyladenosine.

Chemical Properties

White to off-white free flowing powder

Uses

N6-Methyladenosine-5''-monophosphate Sodium Salt is used in method for improving the yield of m6A antibody enriched methylated mRNA.

Uses

N6-Methyladenosine 5′-monophosphate sodium salt can be used in N6-methyladenosine (m6A) ribonucleoprotein immunoprecipitation reactions. m6A has gained a lot of attention in the recent years because the mRNA modification with m6A has been shown to play a role in stability and translational efficiency of mRNA.

Biochem/physiol Actions

A glycogen phosphorylase b activator.

References

[1] MICHEL MORANGF. AMP Analogs: Their Function in the Activation of Glycogen Phosphorylase b[J]. The FEBS journal, 1976, 65 2: 553-563. DOI: 10.1111/j.1432-1033.1976.tb10373.x
[2] TON T. HAI. Species- or isozyme-specific enzyme inhibitors. 7. Selective effects in inhibitions of rat adenylate kinase isozymes by adenosine 5’-phosphate derivatives[J]. Journal of Medicinal Chemistry, 1982, 25 7: 806-812. DOI: 10.1021/jm00349a008
[3] NATE J FRY. N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs.[J]. RNA, 2017, 23 9: 1444-1455. DOI: 10.1261/rna.061044.117

N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT Suppliers

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81921-35-9, N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALTRelated Search:

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE 2'-DEOXYADENOSINE 5'-MONOPHOSPHATE SODIUM SALT ADENOSINE5'-MONOPHOSPHATESODIUMSALT 2'-Deoxyadenosine 5'-phosphate (+/-)-DIHYDROZEATIN RIBOSIDE 5'-MONOPHOSPHATE DISODIUM SALT MONOHYDRATE N6-METHYL-2'-DEOXY-ADENOSINE KINETIN RIBOSIDE 5'-MONOPHOSPHATE DISODIUM SALT 5'-PUMP SODIUM SALT SODIUM GLYCEROPHOSPHATE HYDRATE Adenosine 5'-monophosphate monohydrate ADENOSINE-5'-MONOPHOSPHATE DISODIUM SALT Sodium phosphate dibasic dodecahydrate N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT

  • N6-methyladenosine 5'-monophosphate*sodium
  • N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT
  • N6-Methyladenosine 5'-Monophosphate sodiuM salt ~98% (HPLC)
  • N6-Methyladenosine 5'-monophosphate sodium salt >=97% (HPLC)
  • ML-210N6-Methyladenosine 5'-monophosphate (sodium salt)
  • N-Methyl-5'-adenylic acid disodium salt
  • 6-Me-5'-AMP
  • N6-Methyladenosine 5'-monophosphate disodium salt
  • N6-Methyladenosine 5'-monophosphate sodium salt (N6-Methyl-AMP)
  • 5'-?Adenylicacid,N-?methyl-?,disodiumsalt(9CI)
  • <i>N</i><sup>6</sup>-Methyladenosine 5′-monophosphate sodium salt
  • N<sup>6</sup>-Methyladenosine 5'-monophosphate sodium salt
  • N6-5&#8242,-Me-AMP
  • 81921-35-9
  • C11H15N5O7PNa
  • C11H16N5O7P2Na
  • C11H15N5O7PxNa
  • NucleosidesBiochemicals and Reagents
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleotide Analogs
  • Oligonucleotide Synthesis
  • Specialty Synthesis