ChemicalBook > CAS DataBase List > o-Cresolphthalein

o-Cresolphthalein

Product Name
o-Cresolphthalein
CAS No.
596-27-0
Chemical Name
o-Cresolphthalein
Synonyms
cresolphthalein;o-Cresolphalein;o-Cresolphthalei;o-cresolphtaleine;O-CRESOLPHTHALEIN;O-Cresolphtnalein;Cresolphthanalein;3,3-Bis(4-hydroxy-;o-CRESOLPHTHLALEIN;TIMTEC-BB SBB006498
CBNumber
CB6392671
Molecular Formula
C22H18O4
Formula Weight
346.38
MOL File
596-27-0.mol
More
Less

o-Cresolphthalein Property

Melting point:
223-225 °C
Boiling point:
401.12°C (rough estimate)
Density 
1.1425 (rough estimate)
refractive index 
1.4400 (estimate)
solubility 
Solubility Slightly soluble in water; soluble in ethanol
form 
powder
pka
9.40(at 25℃)
color 
Clear colorless
PH Range
8.2 (colorless) - 9.8 (violet/red)
Water Solubility 
slightly soluble
λmax
566nm, 381nm
Merck 
14,2576
BRN 
310554
Major Application
Sensors, display device, photoresists, recording materials, imaging materials, authentication system for secure documents, decoder system, lithium cells, electroplating process, inks, markers, toners, correction fluid, paints, adhesives, floor coatings, gas leaking detector for safety in industries, toys, food storage, diapers, determination of calcium, lotions, urine analysis test strips, drugs, blood analysis
InChIKey
CPBJMKMKNCRKQB-UHFFFAOYSA-N
CAS DataBase Reference
596-27-0(CAS DataBase Reference)
EPA Substance Registry System
1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-3-methylphenyl)- (596-27-0)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
40-36/37/38-20/21/22
Safety Statements 
36/37-36-26
RIDADR 
1170
WGK Germany 
3
RTECS 
SM8390000
TSCA 
Yes
HS Code 
3822.19.0080
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H340May cause genetic defects

H360May damage fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P308+P313IF exposed or concerned: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C85778
Product name
o-Cresolphthalein
Purity
indicator grade
Packaging
10g
Price
$58.4
Updated
2024/03/01
TCI Chemical
Product number
C0404
Product name
o-Cresolphthalein
Packaging
25g
Price
$65
Updated
2024/03/01
TCI Chemical
Product number
C0404
Product name
o-Cresolphthalein
Packaging
100g
Price
$171
Updated
2024/03/01
Alfa Aesar
Product number
A12899
Product name
o-Cresolphthalein
Packaging
10g
Price
$35.7
Updated
2024/03/01
Alfa Aesar
Product number
A12899
Product name
o-Cresolphthalein
Packaging
50g
Price
$113
Updated
2024/03/01
More
Less

o-Cresolphthalein Chemical Properties,Usage,Production

Chemical Properties

white to pink or beige to tan powder. soluble in ethanol, ether, glacial acetic acid, soluble in dilute alkali and turns purple, slightly soluble in water, hardly soluble in benzene.

Uses

O-Cresolphthalein has been used as a component in calcifying media for calcification assay. It is also used as an indicator (pH range, 8.2 colorless, 9.8 red) and analytical reagent.

Application

O-Cresolphthalein is a gadolinium chelate that is used as a contrast agent for magnetic resonance imaging (MRI) of the brain, spine, and joints. The gadolinium ion is bound to the cresol molecule, which has an attached hydroxyl group. This complex attaches to the phosphorous pentoxide and creates a precipitate of metal hydroxides in the presence of water and sodium carbonate. O-Cresolphthalein is also used in clinical pathology to measure glomerular filtration rate (GFR), which is important for diagnosing renal disease. MRI scans are used to diagnose osteogenic genes that are associated with bone diseases such as osteoporosis.

Biochem/physiol Actions

o-Cresolphthalein is a reversible pH indicator. The kinetics of the reverse pathway (red-purple to colorless) is slow, thereby making it an appropriate molecule to check flow patterns in ducts with corrugated walls. It is also used for the colorimetric determination of calcium content via the o-cresolphthalein complexone method. Binding of calcium to o-cresolphthalein, in the presence of alkaline conditions (pH 10-12), results in the formation of a red complex with an absorbance at 570-575nm.

o-Cresolphthalein Preparation Products And Raw materials

Raw materials

ORTHO TOLUENE Zinc chloride o-Cresol Dilute hydrochloric acid

Preparation Products

More
Less

o-Cresolphthalein Suppliers

Americas 1 Austria 1 Canada 1 China 232 Europe 3 Germany 3 India 39 Japan 5 Poland 1 Switzerland 2 United Kingdom 10 United States 35 Global 333
Anhui Tianjia Chemical Science & Technology Co.,Ltd.
Tel
0550-2392698 18355069969
Fax
0550-2392698
Email
tianjiachem@hotmail.com
Country
China
ProdList
17
Advantage
57
Shenyang Xianchuang Chemical Co., Ltd.
Tel
024-23769576 13840269002
Fax
024-23769576
Email
274311108@qq.com
Country
China
ProdList
359
Advantage
58
SHENYANG SINOCHEM BIOTECH CO.,LTD
Tel
024-23769576 13840269002
Email
274311108@qq.com
Country
China
ProdList
392
Advantage
58
Shenyang Shengyuan chemical industry co., ltd
Tel
13190211560 13190211560
Email
1319074246@qq.com
Country
China
ProdList
94
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
Tangshan Moneide Trading Co., Ltd.
Tel
0315-8309571 15633399667
Fax
+86-315-7726572
Email
sales@moneidechem.com
Country
China
ProdList
704
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
Shanghai Ruji Biology Technology Co., Ltd.
Tel
+86-21-65211385-8001 36031160
Fax
+86-21-65211385-8004
Email
sales@shruji.com
Country
China
ProdList
3224
Advantage
55
Shanghai BeiZhuo Biotech Co., Ltd.
Tel
021-61119791,13386096464
Fax
021-50190009
Email
bzswkf@foxmail.com
Country
China
ProdList
3924
Advantage
50
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3585
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4928
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13358
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
13096311329 028-88469284 616445927
Fax
028-88469284
Email
616445927@qq.com
Country
China
ProdList
2876
Advantage
50
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9972
Advantage
58
Beijing NuoqiYa Biotechnology Co., Ltd.
Tel
4000-819-385 010-62329685 13718666987
Fax
010-62340519
Country
China
ProdList
1971
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Hangzhou Dingyan Chem Co., LTD
Tel
0571-0571-87157530-8001-8006 18049756717
Fax
0571-87156470
Email
sales@dingyanchem.com
Country
China
ProdList
1997
Advantage
58
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
VWR(Shanghai) Co., Ltd
Tel
400-821-8006
Fax
+86-21-58558801
Email
info_china@vwr.com
Country
China
ProdList
3041
Advantage
75
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9947
Advantage
58
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Raw material medicin reagent co.,Ltd
Tel
025-57798860
Email
sales@njromanme.com
Country
China
ProdList
4534
Advantage
58
Qingdao Jade New Material Technology
Tel
0532-68077006 13658692156
Fax
0532-68077006
Email
zandrew@jadenmtc.com
Country
China
ProdList
307
Advantage
58
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9951
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
9859
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13360
Advantage
58
More
Less

View Lastest Price from o-Cresolphthalein manufacturers

Shenyang Simchoice Chemical Co.,Ltd
Product
o-Cresolphthalein 596-27-0
Price
US $18.50/Kg/Drum
Min. Order
25KG
Purity
95.0%
Supply Ability
500kg per month
Release date
2020-08-11
Hebei Kingfiner Technology Development Co.Ltd
Product
o-Cresolphthalein 596-27-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2023-08-11
Baoji Guokang Bio-Technology Co., Ltd.
Product
o-Cresolphthalein 596-27-0
Price
US $48.00/Kg/Drum
Min. Order
25KG
Purity
98%
Supply Ability
1-10mt
Release date
2021-06-02

596-27-0, o-CresolphthaleinRelated Search:

CHLOROPHOSPHONAZO III Furazolidone Tetrahydrofuran Phenolphthalein o-Cresol FURFURYL ALCOHOL RESIN Chlorodimethylphenylsilane Phenylacetone THYMOLPHTHALEIN MONOPHOSPHATE DISODIUM SALT Thymolphthalein Complexone Thymolphthalein monophosphate 2-amino-2-methyl-1,3-propanediol salt O-CRESOLPHTHALEIN COMPLEXONE TETRASODIUM SALT BCECF-AM PHENOLPHTHALEIN COMPLEXONE O-Methyl phenolic epoxy resin Carbofuran THYMOLPHTHALEIN MONOPHOSPHATE MAGNESIUM SALT Thymolphthalein complexone disodium salt

  • 3’,3’’-dimethyl-phenolphthalei
  • cresolphthalein
  • Di-o-Cresolphthalide
  • o-Cresolphalein
  • o-cresolphtaleine
  • 3,3-bis(4-hydroxy-3-methylphenyl)-(3H)-Isobenzofuranone
  • 3,3-bis(4-hydroxy-3-methylphenyl)-1(3h)-isobenzofuranon
  • 3,3-Bis(4-hydroxy-3-methylphenyl)-1-(3H)-iso-benzofuranone
  • 3,3-bis(4-hydroxy-3-methylphenyl)-1(3h)-isobenzofuranone
  • 3,3'-DIMETHYLPHENOLPHTHALEIN
  • LABOTEST-BB LT00451717
  • O-CRESOLPHTHALEIN
  • TIMTEC-BB SBB006498
  • 3,3-bis(4-hydroxy-m-tolyl)phthalide
  • o-Cresollphthalein (0.04% in ca. ethanol)
  • o-Cresolphthalein (0.1% in ca. 90% ethanol)
  • ortho-cresolphthalein
  • 3,3-Bis(3-methyl-4-hydroxyphenyl)phthalide
  • 3,3-Bis(4-hydroxy-3-methylphenyl)-2-benzofuran-1-one
  • O-CRESOLPHTHALEIN INDICATOR
  • ORTHO-CRESOLPHTHALEIN, INDICATOR GRADE
  • O-Cresolphthaleine(PhIndicator)
  • O-Cresolphtnalein
  • o-CRESOLPHTHALEIN (pH INDICATOR)
  • o-Cresolphthalein/CH
  • o-Cresolphthalein, indicator grade, pure
  • o-Cresolphthalein (0.04% in ca. 95% Ethanol) [for pH Determination]
  • 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-3-methylphenyl)-
  • Cresolphthanalein
  • o-Cresolphthalein p.a.
  • o-CRESOLPHTHALEIN SOLUTION 0.04% in ALCOHOL
  • o-Cresolphthalein (0.1% in ca. 90% Ethanol) [for Titration]
  • 3,3-Bis(3-methyl-4-hydroxyphenyl)isobenzofuran-1(3H)-one
  • 3,3-Bis(4-hydroxy-3-methylphenyl)isobenzofuran-1(3H)-one
  • o-Cresolphthalein, indicator grade,98%
  • o-Cresolphthalein,pure,indicator grade
  • (0.04% in ca. 95% Ethanol) [for pH DeterMination]
  • o-Cresolphthalein&nbsp
  • o-Cresolphthalei
  • 3,3-Bis(4-hydroxy-3-methylphenyl)
  • o-Cresolphthalein USP/EP/BP
  • O-cresolphthalein indicator (8.2-9.8)
  • 3,3-Bis(4-hydroxy-
  • O-Cresolphthalein CAS 596-27-0
  • O-Cresolphthalein extrapure 5GM
  • O-Cresolphthalein extrapure 25GM
  • o-Cresolphthalein - Cas NO.: 596-27-0
  • o-Cresolphthalein AR, 95%
  • O-cresolphthalein alcohol soluble
  • o-methylphenolphthalein
  • o-CRESOLPHTHLALEIN
  • 596-27-0
  • 5966-27-0
  • C22H18C4
  • C33H18O4
  • C22H18O4
  • Indicator (pH)
  • pH Indicators