ChemicalBook > CAS DataBase List > 2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid

2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid

Product Name
2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
CAS No.
944561-45-9
Chemical Name
2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
Synonyms
Propynyl-PEG1-Ac;Propargyl-PEG1-CH2COOH;Propargyl-PEG1-acetic Acid;2-(2-prop-2-ynoxyethoxy)acetic acid;2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid;Acetic acid, 2-[2-(2-propyn-1-yloxy)ethoxy]-
CBNumber
CB63975392
Molecular Formula
C7H10O4
Formula Weight
158.15
MOL File
944561-45-9.mol
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2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid Property

Boiling point:
294.2±20.0 °C(Predicted)
Density 
1.169±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Liquid
pka
3.37±0.10(Predicted)
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS104180
Product name
2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
Purity
95+%
Packaging
250mg
Price
$294
Updated
2021/12/16
AK Scientific
Product number
0351EB
Product name
2-[2-(2-Propyn-1-yloxy)ethoxy]aceticacid
Packaging
100mg
Price
$310
Updated
2021/12/16
Activate Scientific
Product number
AS104180
Product name
2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
Purity
95+%
Packaging
1g
Price
$585
Updated
2021/12/16
AK Scientific
Product number
0351EB
Product name
2-[2-(2-Propyn-1-yloxy)ethoxy]aceticacid
Packaging
2.5g
Price
$1535
Updated
2021/12/16
AK Scientific
Product number
0351EB
Product name
2-[2-(2-Propyn-1-yloxy)ethoxy]aceticacid
Packaging
5g
Price
$2222
Updated
2021/12/16
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2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid Chemical Properties,Usage,Production

Uses

Propynyl-PEG1-Ac is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propynyl-PEG1-Ac is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid Suppliers

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944561-45-9, 2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acidRelated Search:

2,5-dioxopyrrolidin-1-yl pent-4-ynoate t-Boc-N-Amido-PEG2-Propargyl Propargyl-PEG5-t-butyl ester Propargyl-PEG4-Tos Propargyl-PEG8-t-butyl ester Propargyl-PEG8-alcohol

  • 2-[2-(2-Propyn-1-yloxy)ethoxy]acetic acid
  • Acetic acid, 2-[2-(2-propyn-1-yloxy)ethoxy]-
  • Propargyl-PEG1-CH2COOH
  • Propynyl-PEG1-Ac
  • 2-(2-prop-2-ynoxyethoxy)acetic acid
  • Propargyl-PEG1-acetic Acid
  • 944561-45-9