4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid

Product Name: 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid
CAS No.: 29553-70-6
Chemical Name: 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid
Synonyms: 4-CPPC (4CPPC);4-CPPC, 10 mM in DMSO;4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid;4-(3-carboxyphenyl)-2,5-pyridinedicarboxylic acid;2,5-Pyridinedicarboxylic acid, 4-(3-carboxyphenyl)-
CBNumber: CB64108052
Molecular Formula: C14H9NO6
Formula Weight: 287.22
MOL File: 29553-70-6.mol

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4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid Property

storage temp.: Store at -20°C
solubility: DMSO: soluble
form: A crystalline solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 30068
Product name: 4-CPPC
Packaging: 1mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 30068
Product name: 4-CPPC
Packaging: 10mg
Price: $486
Updated: 2024/03/01

Cayman Chemical

Product number: 30068
Product name: 4-CPPC
Packaging: 500μg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 30068
Product name: 4-CPPC
Packaging: 5mg
Price: $275
Updated: 2024/03/01

AK Scientific

Product number: 0509CE
Product name: 4-(3-Carboxyphenyl)pyridine-2,5-dicarboxylicAcid
Packaging: 5mg
Price: $403
Updated: 2021/12/16

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4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid Chemical Properties,Usage,Production

Uses

4-CPPC is a potent, reversible and selective MIF-2 inhibitor with Ki values of 431, 33 μM for MIF-1, MIF-2, respectively[1].

Biological Activity

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2; IC50 = 27 μM).1 It is selective for MIF-2 over MIF-1 (IC50 = 450 μM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 μM. 4-CPPC (5, 10, and 25 μM) inhibits MIF-2-induced ERK1/2 phosphorylation in primary human skin fibroblasts.

References

1.Tilstam, P.V., Pantouris, G., Corman, M., et al.A selective small-molecule inhibitor of macrophage migration inhibitory factor-2 (MIF-2), a MIF cytokine superfamily member, inhibits MIF-2 biological activityJ. Biol. Chem.294(49)18522-18531(2019)

4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid Suppliers

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29553-70-6, 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acidRelated Search:

4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid

4-CPPC (4CPPC)

2,5-Pyridinedicarboxylic acid, 4-(3-carboxyphenyl)-

4-(3-carboxyphenyl)-2,5-pyridinedicarboxylic acid

4-CPPC, 10 mM in DMSO

29553-70-6