ChemicalBook > CAS DataBase List > Ethyl diethoxyphosphinylformate
Ethyl diethoxyphosphinylformate
- Product Name
- Ethyl diethoxyphosphinylformate
- CAS No.
- 1474-78-8
- Chemical Name
- Ethyl diethoxyphosphinylformate
- Synonyms
- Foscarnet EP Impurity D;Foscarnet impurity D CRS;TRIETHYL PHOSPHONOFORMATE;Triethyl carboxyphosphonate;Triethyl phosphonomethanoate;Foscarnet Related CoMpound D;Diethyl carbethoxyphosphonate;TRIETHYL PHOSPHONOFORMATE 98%;Foscarnet Sodium EP Impurity D;ethyl diethyl-phosphonoformate
- CBNumber
- CB6423762
- Molecular Formula
- C7H15O5P
- Formula Weight
- 210.16
- MOL File
- 1474-78-8.mol
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Ethyl diethoxyphosphinylformate Property
- Boiling point:
- 135 °C12 mm Hg(lit.)
- Density
- 1.11 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.423(lit.)
- Flash point:
- >230 °F
- storage temp.
- Store below +30°C.
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- color
- Colorless to Almost colorless
- Specific Gravity
- 1.11
- BRN
- 1781949
- Stability:
- Moisture Sensitive
- CAS DataBase Reference
- 1474-78-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Phosphinecarboxylic acid, diethoxy-, ethyl ester, oxide(1474-78-8)
- EPA Substance Registry System
- Phosphinecarboxylic acid, diethoxy-, ethyl ester, oxide (1474-78-8)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-43
- Safety Statements
- 24/25-36/37-26-37-24
- WGK Germany
- 3
- TSCA
- Yes
- HS Code
- 2931 39 90
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P321Specific treatment (see … on this label).
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PHR2870
- Product name
- Foscarnet Related Compound D
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 0.5ML
- Price
- $634
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 1283324
- Product name
- Foscarnet Related Compound D
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 0.27ml
- Price
- $1140
- Updated
- 2024/03/01
TCI Chemical
- Product number
- E0400
- Product name
- Ethyl Diethoxyphosphinylformate
- Packaging
- 25g
- Price
- $40
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- B23367
- Product name
- Ethyl diethoxyphosphinylformate, 97+%
- Packaging
- 100g
- Price
- $46.4
- Updated
- 2021/12/16
Alfa Aesar
- Product number
- B23367
- Product name
- Ethyl diethoxyphosphinylformate, 97+%
- Packaging
- 25g
- Price
- $16.7
- Updated
- 2021/12/16
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Ethyl diethoxyphosphinylformate Chemical Properties,Usage,Production
Chemical Properties
Clear colorless to slightly yellow liquid
Uses
Diethyl (Ethoxycarbonyl)phosphonate is an impurity in the synthesis of Foscarnet (F727400), an inhibitor of viral DNA polymerase and reverse transcriptase. Foscarnet is used as an antiviral.
General Description
for synthesis
Purification Methods
Dissolve it in Et2O, shake this with H2O (to remove any trace of NaCl impurity), dry (Na2SO4), evaporate and distil it using an efficient fractionating column. [Nylén Chem Ber 57 1035 1924, Reetz et al. J Am Chem Soc 77 3813 1955, Monson Advanced Organic Synthesis Academic Press p 89 1972, Beilstein 3 II 103.]
Ethyl diethoxyphosphinylformate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl diethoxyphosphinylformate manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- Triethyl Phosphonoformate 1474-78-8
- Price
- US $1.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2020-01-14
Career Henan Chemical Co
- Product
- Ethyl diethoxyphosphinylformate 1474-78-8
- Price
- US $1.00/ASSAYS
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2019-12-31
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