Description Source Background
ChemicalBook > CAS DataBase List > OSTEONECTIN, BOVINE

OSTEONECTIN, BOVINE

Description Source Background
Product Name
OSTEONECTIN, BOVINE
Chemical Name
OSTEONECTIN, BOVINE
Synonyms
SPARC;BM-40;OSTEONECTIN;SPARC, HUMAN;BM-40, HUMAN;SPARC, BOVINE;BM-40, BOVINE;OSTEONECTIN, HUMAN;OSTEONECTIN, BOVINE;OSTEONECTIN, BOVINE BONE
CBNumber
CB6429153
Formula Weight
0
MOL File
Mol file
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OSTEONECTIN, BOVINE Property

storage temp. 
−20°C
form 
lyophilized powder
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
145212
Product name
SPARC
Packaging
100ug
Price
$490
Updated
2021/12/16
Usbiological
Product number
S5370-25
Product name
SPARC
Packaging
1mg
Price
$531
Updated
2021/12/16
Usbiological
Product number
359008
Product name
Sparc
Packaging
48Tests
Price
$588
Updated
2021/12/16
Usbiological
Product number
353045
Product name
SPARC
Packaging
96Tests
Price
$719
Updated
2021/12/16
Biorbyt Ltd
Product number
orb528094
Product name
SPARC
Packaging
10μg
Price
$290.7
Updated
2021/12/16
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OSTEONECTIN, BOVINE Chemical Properties,Usage,Production

Description

Secreted Protein Acidic & Rich in Cysteine Human Recombinant produced in E.Coli is a single, non- glycosylated polypeptide chain containing 286 amino acids and having a molecular mass of 32.7kDa.
SPARC is purified by proprietary chromatographic techniques.

Source

Escherichia Coli

Background

SPARC, an acronym for “secreted protein, acidic and rich in cysteine”, is also known as osteonectin or BM-40. It is the founding member of a family of secreted matricellular proteins with similar domain structure. The 303 amino acid, 43 kDa protein contains a 17 aa signal sequence, an N-terminal acidic region that binds calcium, a follistatin domain containing Kazal-like sequences, and a C-terminal extracellular calcium (EC) binding domain with two EF-hand motifs. SPARC is produced by fibroblasts, capillary endothelial cells, platelets and macrophages, especially in areas of tissue morphogenesis and remodeling. SPARC shows context-specific effects, but generally inhibits adhesion, spreading and proliferation, and promotes collagen matrix formation. For endothelial cells, SPARC disrupts focal adhesions and binds and sequesters PDGF and VEGF. SPARC is abundantly expressed in bone, where it promotes osteoblast differentiation and inhibits adipogenesis.

OSTEONECTIN, BOVINE Preparation Products And Raw materials

Raw materials

Preparation Products

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OSTEONECTIN, BOVINERelated Search:

Mouse LRRC15 HUMAN IGF-II TEV Protease TRGC1 Laminin 211 SLAMF1 Huntingtin Recombinant Human CD27 Ligand/TNFSF7/CD70 (C-Fc) Enhancer of polycomb homolog 1 MPIF-1

  • BM-40
  • BM-40, BOVINE
  • BM-40, HUMAN
  • OSTEONECTIN
  • OSTEONECTIN, BOVINE BONE
  • OSTEONECTIN, HUMAN
  • OSTEONECTIN, HUMAN PLATELETS
  • SPARC
  • SPARC, HUMAN
  • OSTEONECTIN, BOVINE
  • SPARC, BOVINE
  • SECRETED PROTEIN ACIDIC AND RICH IN CYSTEINE
  • SPARC from murine parietal yolk sac (PYS-2) cells
  • BM-40, Osteonectin, Secreted protein acidic and rich in cysteine
  • Human SPARC Protein, His Tag
  • Recombinant Human SPARC Protein, His Tag